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IPR018215 is a ClpP, Ser active site.
<p>Clp is an ATP-dependent protease that cleaves a number of proteins, such as casein and albumin [[cite:PUB00002564]]. It exists as a heterodimer of ATP-binding regulatory A and catalytic P subunits, both of which are required for effective levels of protease activity in the presence of ATP [[cite:PUB00002564]], although the P subunit alone does possess some catalytic activity.</p> <p>Proteases highly similar to ClpP have been found to be encoded in the genome of bacteria, metazoa, some viruses and in the chloroplast of plants. A number of the proteins in this family are classified as non-peptidase homologues as they have been found experimentally to be without peptidase activity, or lack amino acid residues that are believed to be essential for catalytic activity.</p> <p>This entry represents a conserved region containing a serine that is involved in the catalytic triad.</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: ATP-dependent Clp protease proteolytic subunit 3, chloroplastic-like [Glycine max] gi|356499630|ref|XP_003518640.1| | 16 | ||
| – | PREDICTED: ATP-dependent Clp protease proteolytic subunit 2, mitochondrial-like [Vitis vinifera] gi|225423749|ref|XP_002277069.1| | 19 | ||
| – | PREDICTED: ATP-dependent Clp protease proteolytic subunit 2, mitochondrial-like isoform 1 [Glycine max] gi|356538559|ref|XP_003537770.1| | 15 | ||
| – | PREDICTED: ATP-dependent Clp protease proteolytic subunit 2, mitochondrial-like isoform 1 [Glycine max] gi|356538559|ref|XP_003537770.1| | 14 | ||
| – | PREDICTED: ATP-dependent Clp protease proteolytic subunit 5, chloroplastic-like isoform 1 [Glycine max] gi|356534756|ref|XP_003535918.1| | 17 | ||
| – | ATP-dependent Clp protease proteolytic subunit [Lotus japonicus] gi|13518463|ref|NP_084822.1| | 15 | ||
| – | ATP-dependent Clp protease proteolytic subunit; TAIR: AT1G66670.1 CLP protease proteolytic subunit 3; Swiss-Prot: sp|Q9SXJ6|CLPP3_ARATH ATP-dependent Clp protease proteolytic subunit 3, chloroplastic; TrEMBL-Plants: tr|I3S6Z8|I3S6Z8_LOTJA ATP-dependent Clp protease proteolytic subunit; Found in the gene: LotjaGi1g1v0544300 | 16 | ||
| – | ATP-dependent Clp protease proteolytic subunit; TAIR: AT5G23140.1 nuclear-encoded CLP protease P7; Swiss-Prot: sp|Q9FN42|CLPP2_ARATH ATP-dependent Clp protease proteolytic subunit 2, mitochondrial; TrEMBL-Plants: tr|I3SVH6|I3SVH6_LOTJA ATP-dependent Clp protease proteolytic subunit; Found in the gene: LotjaGi3g1v0529000 | 15 | ||
| – | ATP-dependent Clp protease proteolytic subunit; TAIR: AT1G02560.1 nuclear encoded CLP protease 5; Swiss-Prot: sp|Q9S834|CLPP5_ARATH ATP-dependent Clp protease proteolytic subunit 5, chloroplastic; TrEMBL-Plants: tr|V7BH24|V7BH24_PHAVU ATP-dependent Clp protease proteolytic subunit; Found in the gene: LotjaGi5g1v0243900 | 21 | ||
| – | ATP-dependent Clp protease proteolytic subunit; TAIR: AT1G02560.1 nuclear encoded CLP protease 5; Swiss-Prot: sp|Q9S834|CLPP5_ARATH ATP-dependent Clp protease proteolytic subunit 5, chloroplastic; TrEMBL-Plants: tr|A0A1J7H2S4|A0A1J7H2S4_LUPAN Uncharacterized protein; Found in the gene: LotjaGi5g1v0243900 | 15 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| cd07017 | CDD | 1 | 10.00 |