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IPR030388 is a Era-type guanine nucleotide-binding (G) domain.
<p>Era (E. coli Ras-like protein) is a small G-protein widely conserved in eubacteria and eukaryotes. It is essential for bacterial cell viability and is required for the maturation of 16S rRNA and assembly of the 30S ribosomal subunit [[cite:PUB00038210]]. Era couples cell growth with cytokinesis and plays a role in cell division and energy metabolism. Era contains an N-terminal GTPase domain and a C-terminal distinct derivative of the type-II RNA-binding KH domain [[cite:PUB00013952], [cite:PUB00072549], [cite:PUB00055805], [cite:PUB00055804]]. Both domains are important for Era function. Era is functionally able to compensate for deletion of RbfA, a cold-shock adaptation protein that is required for efficient processing of the 16S rRNA.</p> <p>The Era-type GTPase domain consists of a central six-stranded β-sheet flanked by five α-helices, in which the GTP-binding site is located. Guanine nucleotide molecules interact with highly conserved G protein regions G1-G5 [[cite:PUB00055805]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | GTP binding | Interacting selectively and non-covalently with GTP, guanosine triphosphate. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: GTP-binding protein ERG-like [Cicer arietinum] gi|502166492|ref|XP_004513909.1| | 18 | ||
| – | PREDICTED: GTPase Era-like [Glycine max] gi|356502167|ref|XP_003519892.1| | 13 | ||
| – | PREDICTED: GTPase Era-like [Glycine max] gi|356502167|ref|XP_003519892.1| | 23 | ||
| – | GTPase Era; TAIR: AT1G30960.1 GTP-binding family protein; Swiss-Prot: sp|O82626|ERG_ANTMA GTP-binding protein ERG; TrEMBL-Plants: tr|G7KDM7|G7KDM7_MEDTR GTP-binding ERG-like protein; Found in the gene: LotjaGi2g1v0003800 | 26 | ||
| – | GTPase Era; TAIR: AT5G66470.1 GTP-binding protein Era-like protein; Swiss-Prot: sp|B2V2K0|ERA_CLOBA GTPase Era; TrEMBL-Plants: tr|V7CCY5|V7CCY5_PHAVU Uncharacterized protein; Found in the gene: LotjaGi4g1v0120100 | 23 | ||
| – | GTPase Era; TAIR: AT5G66470.1 GTP-binding protein Era-like protein; Swiss-Prot: sp|B2V2K0|ERA_CLOBA GTPase Era; TrEMBL-Plants: tr|V7CCY5|V7CCY5_PHAVU Uncharacterized protein; Found in the gene: LotjaGi4g1v0120100 | 28 | ||
| – | GTPase Era; TAIR: AT5G66470.1 GTP-binding protein Era-like protein; Swiss-Prot: sp|B2V2K0|ERA_CLOBA GTPase Era; TrEMBL-Plants: tr|A0A0S3R4P9|A0A0S3R4P9_PHAAN Uncharacterized protein; Found in the gene: LotjaGi4g1v0120100 | 22 | ||
| – | GTPase Era; TAIR: AT5G66470.1 GTP-binding protein Era-like protein; Swiss-Prot: sp|B2V2K0|ERA_CLOBA GTPase Era; TrEMBL-Plants: tr|A0A0S3R4P9|A0A0S3R4P9_PHAAN Uncharacterized protein; Found in the gene: LotjaGi4g1v0120100 | 22 | ||
| – | GTPase Era; TAIR: AT5G66470.1 GTP-binding protein Era-like protein; Swiss-Prot: sp|B2V2K0|ERA_CLOBA GTPase Era; TrEMBL-Plants: tr|A0A0S3R4P9|A0A0S3R4P9_PHAAN Uncharacterized protein; Found in the gene: LotjaGi4g1v0120100 | 20 | ||
| – | GTPase Era; TAIR: AT5G66470.1 GTP-binding protein Era-like protein; Swiss-Prot: sp|B0TAF1|ERA_HELMI GTPase Era; TrEMBL-Plants: tr|A0A0L9TNW9|A0A0L9TNW9_PHAAN Uncharacterized protein; Found in the gene: LotjaGi4g1v0120100 | 23 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| cd04163 | CDD | 1 | 10.00 |