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IPR035639 is a CPSF2, metallo-hydrolase domain.
<p>Cleavage and polyadenylation specificity factor (CPSF) plays a key role in pre-mRNA 3'-end formation, recognising the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition [[cite:PUB00062835]].</p> <p>This entry represents a metallo-hydrolase domain in subunit 2. In addition to this metallo-beta-lactamase (MBL)-fold metallo-hydrolase domain, subunit 2 contains a beta-CASP (named for metallo-beta-lactamase, CPSF, Artemis, Snm1, Pso2) domain [[cite:PUB00014290]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | Cleavage and polyadenylation specificity factor subunit 2; TAIR: AT5G23880.1 cleavage and polyadenylation specificity factor 100; Swiss-Prot: sp|Q9LKF9|CPSF2_ARATH Cleavage and polyadenylation specificity factor subunit 2; TrEMBL-Plants: tr|A0A1J7HZX4|A0A1J7HZX4_LUPAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0141300 | 17 | ||
| – | Cleavage and polyadenylation specificity factor subunit 2; TAIR: AT5G23880.1 cleavage and polyadenylation specificity factor 100; Swiss-Prot: sp|Q9LKF9|CPSF2_ARATH Cleavage and polyadenylation specificity factor subunit 2; TrEMBL-Plants: tr|A0A1J7HZX4|A0A1J7HZX4_LUPAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0141300 | 11 | ||
| – | Cleavage and polyadenylation specificity factor subunit 2-like protein; TAIR: AT5G23880.1 cleavage and polyadenylation specificity factor 100; Swiss-Prot: sp|Q9LKF9|CPSF2_ARATH Cleavage and polyadenylation specificity factor subunit 2; TrEMBL-Plants: tr|A0A0B0PTU3|A0A0B0PTU3_GOSAR Cleavage and polyadenylation specificity factor subunit 2-like protein; Found in the gene: LotjaGi2g1v0141300 | 15 | ||
| – | Cleavage and polyadenylation specificity factor subunit 2; TAIR: AT5G23880.1 cleavage and polyadenylation specificity factor 100; Swiss-Prot: sp|Q9LKF9|CPSF2_ARATH Cleavage and polyadenylation specificity factor subunit 2; TrEMBL-Plants: tr|A0A1J7HZX4|A0A1J7HZX4_LUPAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0141300 | 17 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| cd16293 | CDD | 1 | 25.00 |