Domain Predictions — View

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IPR027075

Source: InterPro

Description

IPR027075 is a Cleavage and polyadenylation specificity factor subunit 2.

<p>Cleavage and polyadenylation specificity factor (CPSF) plays a key role in pre-mRNA 3'-end formation, recognising the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition [[cite:PUB00062835]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on April 27, 2020, while the GO metadata was last updated on April 27, 2020.

GO term	Namespace	Name	Definition	Relationships
GO:0005847 View details of GO:0005847 AmiGO InterPro QuickGO	Cellular component	MRNA cleavage and polyadenylation specificity factor complex	A multisubunit complex that binds to the canonical AAUAAA hexamer and to U-rich upstream sequence elements on the pre-mRNA, thereby stimulating the otherwise weakly active and nonspecific polymerase to elongate efficiently RNAs containing a poly(A) signal.	Subterm of GO:0005849
GO:0006378 View details of GO:0006378 AmiGO InterPro QuickGO	Biological process	MRNA polyadenylation	The enzymatic addition of a sequence of 40-200 adenylyl residues at the 3' end of a eukaryotic mRNA primary transcript.	Subterm of GO:0031124 GO:0043631
GO:0006379 View details of GO:0006379 AmiGO InterPro QuickGO	Biological process	MRNA cleavage	Any process in which a pre-mRNA or mRNA molecule is cleaved at specific sites or in a regulated manner.	Subterm of GO:0016071 GO:0090501

Associated Lotus transcripts 7

Transcript	Name	Description	Predicted domains	Domain count
Lj0g3v0106869.1 View transcript LORE1 v3.0 Genome browser Expression Atlas (ExpAt)	–	PREDICTED: cleavage and polyadenylation specificity factor subunit 2-like isoform 2 [Glycine max] gi\|356530858\|ref\|XP_003533996.1\|	Domains Coil IPR001279 IPR011108 IPR025069 IPR027075 PF07521 PF13299 PTHR11203 PTHR11203:SF5 SSF56281	10
Lj2g3v0392950.1 View transcript LORE1 v3.0 Genome browser Expression Atlas (ExpAt)	–	PREDICTED: cleavage and polyadenylation specificity factor subunit 2-like isoform 1 [Glycine max] gi\|356559788\|ref\|XP_003548179.1\|	Domains G3DSA:3.60.15.10 IPR001279 IPR022712 IPR027075 PF10996 PF16661 PTHR11203 PTHR11203:SF5 SM01027 SSF56281	10
LotjaGi2g1v0141300.1 View transcript LORE1 v3.0 Genome browser Expression Atlas (ExpAt)	–	Cleavage and polyadenylation specificity factor subunit 2; TAIR: AT5G23880.1 cleavage and polyadenylation specificity factor 100; Swiss-Prot: sp\|Q9LKF9\|CPSF2_ARATH Cleavage and polyadenylation specificity factor subunit 2; TrEMBL-Plants: tr\|A0A1J7HZX4\|A0A1J7HZX4_LUPAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0141300	Domains Coil G3DSA:3.60.15.10 IPR001279 IPR011108 IPR022712 IPR025069 IPR027075 IPR035639 IPR036866 PF07521 PF10996 PF13299 PF16661 PTHR45922 SM01027 SSF56281 cd16293	17
LotjaGi2g1v0141300.2 View transcript LORE1 v3.0 Genome browser Expression Atlas (ExpAt)	–	Cleavage and polyadenylation specificity factor subunit 2; TAIR: AT5G23880.1 cleavage and polyadenylation specificity factor 100; Swiss-Prot: sp\|Q9LKF9\|CPSF2_ARATH Cleavage and polyadenylation specificity factor subunit 2; TrEMBL-Plants: tr\|A0A1J7HZX4\|A0A1J7HZX4_LUPAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0141300	Domains G3DSA:3.60.15.10 IPR001279 IPR022712 IPR027075 IPR035639 IPR036866 PF10996 PF16661 PTHR45922 SSF56281 cd16293	11
LotjaGi2g1v0141300.3 View transcript LORE1 v3.0 Genome browser Expression Atlas (ExpAt)	–	Cleavage and polyadenylation specificity factor subunit 2-like protein; TAIR: AT5G23880.1 cleavage and polyadenylation specificity factor 100; Swiss-Prot: sp\|Q9LKF9\|CPSF2_ARATH Cleavage and polyadenylation specificity factor subunit 2; TrEMBL-Plants: tr\|A0A0B0PTU3\|A0A0B0PTU3_GOSAR Cleavage and polyadenylation specificity factor subunit 2-like protein; Found in the gene: LotjaGi2g1v0141300	Domains Coil G3DSA:3.40.50.10890 G3DSA:3.60.15.10 IPR001279 IPR011108 IPR025069 IPR027075 IPR035639 IPR036866 PF07521 PF13299 PF16661 PTHR45922 SSF56281 cd16293	15
LotjaGi2g1v0141300.4 View transcript LORE1 v3.0 Genome browser Expression Atlas (ExpAt)	–	Cleavage and polyadenylation specificity factor subunit 2; TAIR: AT5G23880.1 cleavage and polyadenylation specificity factor 100; Swiss-Prot: sp\|Q9LKF9\|CPSF2_ARATH Cleavage and polyadenylation specificity factor subunit 2; TrEMBL-Plants: tr\|A0A1J7HZX4\|A0A1J7HZX4_LUPAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0141300	Domains Coil G3DSA:3.60.15.10 IPR001279 IPR011108 IPR022712 IPR025069 IPR027075 IPR035639 IPR036866 PF07521 PF10996 PF13299 PF16661 PTHR45922 SM01027 SSF56281 cd16293	17
LotjaGi2g1v0141300.5 View transcript LORE1 v3.0 Genome browser Expression Atlas (ExpAt)	–	Cleavage and polyadenylation specificity factor subunit 2; TAIR: AT5G23880.1 cleavage and polyadenylation specificity factor 100; Swiss-Prot: sp\|Q9LKF9\|CPSF2_ARATH Cleavage and polyadenylation specificity factor subunit 2; TrEMBL-Plants: tr\|A0A1J7HZX4\|A0A1J7HZX4_LUPAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0141300	Domains Coil G3DSA:3.40.50.10890 G3DSA:3.60.15.10 IPR001279 IPR011108 IPR022712 IPR025069 IPR027075 IPR036866 PF07521 PF10996 PF13299 PF16661 PTHR45922 SM01027 SSF56281	16

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain	Source	Observations	Saturation (%)
SSF56281	SUPERFAMILY	1	14.29