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PF00389

Source: Pfam

Description

D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0016616
Molecular function Oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP.
Subterm of
GO:0051287
Molecular function NAD binding Interacting selectively and non-covalently with nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NAD+, or the reduced form, NADH.
Subterm of
GO:0055114
Biological process Oxidation-reduction process A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
Subterm of

Associated Lotus transcripts 36

Transcript Name Description Predicted domains Domain count
Lj0g3v0067359.1
– PREDICTED: d-3-phosphoglycerate dehydrogenase, chloroplastic-like [Glycine max] gi|356521735|ref|XP_003529507.1|
Domains
15
Lj0g3v0130969.1
– PREDICTED: d-3-phosphoglycerate dehydrogenase-like isoform X2 [Cicer arietinum] gi|502127464|ref|XP_004499721.1|
Domains
13
Lj0g3v0310809.1
–
Domains
17
Lj0g3v0310819.1
– PREDICTED: d-3-phosphoglycerate dehydrogenase, chloroplastic-like [Glycine max] gi|356521735|ref|XP_003529507.1|
Domains
22
Lj0g3v0361499.1
–
Domains
13
Lj2g3v1014170.1
– Formate dehydrogenase [Lotus japonicus] gi|211970690|emb|CAR98204.1|
Domains
24
Lj2g3v1014180.1
– Formate dehydrogenase [Lotus japonicus] gi|211970690|emb|CAR98204.1|
Domains
24
Lj2g3v2002800.1
– Glyoxylate reductase [Medicago truncatula] gi|357468403|ref|XP_003604486.1|
Domains
11
Lj2g3v2002820.1
–
Domains
13
Lj2g3v2002820.2
–
Domains
13
Lj2g3v2002840.1
– PREDICTED: glyoxylate/hydroxypyruvate reductase A HPR2-like [Cicer arietinum] gi|502147592|ref|XP_004506841.1|
Domains
13
Lj3g3v0235170.1
– PREDICTED: glyoxylate/hydroxypyruvate reductase A HPR2-like [Cicer arietinum] gi|502081028|ref|XP_004486744.1|
Domains
13
Lj3g3v2720150.1
– PREDICTED: glyoxylate/hydroxypyruvate reductase HPR3-like [Cicer arietinum] gi|502157767|ref|XP_004510901.1|
Domains
13
Lj3g3v2720150.2
– PREDICTED: glyoxylate/hydroxypyruvate reductase HPR3-like [Cicer arietinum] gi|502157770|ref|XP_004510902.1|
Domains
10
Lj4g3v2917540.1
– PREDICTED: glyoxylate/hydroxypyruvate reductase A HPR2-like [Cicer arietinum] gi|502147592|ref|XP_004506841.1|
Domains
13
Lj5g3v2113470.1
– PREDICTED: d-3-phosphoglycerate dehydrogenase, chloroplastic-like [Glycine max] gi|356536156|ref|XP_003536605.1|
Domains
18
Lj5g3v2113470.2
– PREDICTED: d-3-phosphoglycerate dehydrogenase, chloroplastic-like [Glycine max] gi|356536156|ref|XP_003536605.1|
Domains
29
Lj5g3v2242500.1
– Peroxisomal hydroxypyruvate reductase [Glycine max] gi|167963236|dbj|BAG09374.1|
Domains
13
LotjaGi2g1v0247200.1
– Formate dehydrogenase; TAIR: AT5G14780.1 formate dehydrogenase; Swiss-Prot: sp|Q07511|FDH_SOLTU Formate dehydrogenase, mitochondrial; TrEMBL-Plants: tr|B6VPZ9|B6VPZ9_LOTJA Formate dehydrogenase, mitochondrial; Found in the gene: LotjaGi2g1v0247200
Domains
24
LotjaGi2g1v0428400_LC.1
– Glyoxylate reductase/hydroxypyruvate reductase; TAIR: AT1G79870.1 D-isomer specific 2-hydroxyacid dehydrogenase family protein; Swiss-Prot: sp|Q65CJ7|HPPR_PLESU Hydroxyphenylpyruvate reductase; TrEMBL-Plants: tr|A0A151SH67|A0A151SH67_CAJCA Glyoxylate reductase; Found in the gene: LotjaGi2g1v0428400_LC
Domains
12
LotjaGi2g1v0428400_LC.2
– Glyoxylate reductase/hydroxypyruvate reductase; TAIR: AT1G79870.1 D-isomer specific 2-hydroxyacid dehydrogenase family protein; Swiss-Prot: sp|Q65CJ7|HPPR_PLESU Hydroxyphenylpyruvate reductase; TrEMBL-Plants: tr|A0A151SH67|A0A151SH67_CAJCA Glyoxylate reductase; Found in the gene: LotjaGi2g1v0428400_LC
Domains
12
LotjaGi2g1v0428600.1
– Glyoxylate reductase/hydroxypyruvate reductase; TAIR: AT1G79870.1 D-isomer specific 2-hydroxyacid dehydrogenase family protein; Swiss-Prot: sp|Q65CJ7|HPPR_PLESU Hydroxyphenylpyruvate reductase; TrEMBL-Plants: tr|G7JJF7|G7JJF7_MEDTR D-glycerate dehydrogenase/hydroxypyruvate reductase; Found in the gene: LotjaGi2g1v0428600
Domains
13
LotjaGi2g1v0428600.2
– Glyoxylate reductase/hydroxypyruvate reductase; TAIR: AT1G79870.1 D-isomer specific 2-hydroxyacid dehydrogenase family protein; Swiss-Prot: sp|Q65CJ7|HPPR_PLESU Hydroxyphenylpyruvate reductase; TrEMBL-Plants: tr|G7JJF7|G7JJF7_MEDTR D-glycerate dehydrogenase/hydroxypyruvate reductase; Found in the gene: LotjaGi2g1v0428600
Domains
13
LotjaGi3g1v0001700.2
– D-3-phosphoglycerate dehydrogenase; TAIR: AT1G17745.1 D-3-phosphoglycerate dehydrogenase; Swiss-Prot: sp|O04130|SERA2_ARATH D-3-phosphoglycerate dehydrogenase 2, chloroplastic; TrEMBL-Plants: tr|A0A1J7IRI9|A0A1J7IRI9_LUPAN Uncharacterized protein; Found in the gene: LotjaGi3g1v0001700
Domains
28
LotjaGi3g1v0018000.1
– Glyoxylate reductase/hydroxypyruvate reductase; TAIR: AT1G79870.1 D-isomer specific 2-hydroxyacid dehydrogenase family protein; Swiss-Prot: sp|Q65CJ7|HPPR_PLESU Hydroxyphenylpyruvate reductase; TrEMBL-Plants: tr|A0A1J6ILY2|A0A1J6ILY2_NICAT Glyoxylatehydroxypyruvate reductase a hpr2; Found in the gene: LotjaGi3g1v0018000
Domains
13
LotjaGi3g1v0335100.1
– D-3-phosphoglycerate dehydrogenase; TAIR: AT1G72190.1 D-isomer specific 2-hydroxyacid dehydrogenase family protein; Swiss-Prot: sp|O29445|SERA_ARCFU D-3-phosphoglycerate dehydrogenase; TrEMBL-Plants: tr|A0A0B2QT46|A0A0B2QT46_GLYSO D-3-phosphoglycerate dehydrogenase; Found in the gene: LotjaGi3g1v0335100
Domains
13
LotjaGi3g1v0335100.2
– D-3-phosphoglycerate dehydrogenase; TAIR: AT1G72190.1 D-isomer specific 2-hydroxyacid dehydrogenase family protein; Swiss-Prot: sp|O29445|SERA_ARCFU D-3-phosphoglycerate dehydrogenase; TrEMBL-Plants: tr|A0A0B2QT46|A0A0B2QT46_GLYSO D-3-phosphoglycerate dehydrogenase; Found in the gene: LotjaGi3g1v0335100
Domains
13
LotjaGi3g1v0343100.1
– D-3-phosphoglycerate dehydrogenase; TAIR: AT1G17745.1 D-3-phosphoglycerate dehydrogenase; Swiss-Prot: sp|O04130|SERA2_ARATH D-3-phosphoglycerate dehydrogenase 2, chloroplastic; TrEMBL-Plants: tr|I1KG47|I1KG47_SOYBN D-3-phosphoglycerate dehydrogenase; Found in the gene: LotjaGi3g1v0343100
Domains
29
LotjaGi3g1v0366700.1
– Glyoxylate reductase/hydroxypyruvate reductase; TAIR: AT1G79870.1 D-isomer specific 2-hydroxyacid dehydrogenase family protein; Swiss-Prot: sp|Q65CJ7|HPPR_PLESU Hydroxyphenylpyruvate reductase; TrEMBL-Plants: tr|G7JJF7|G7JJF7_MEDTR D-glycerate dehydrogenase/hydroxypyruvate reductase; Found in the gene: LotjaGi3g1v0366700
Domains
13
LotjaGi3g1v0366700.2
– Glyoxylate reductase/hydroxypyruvate reductase; TAIR: AT1G79870.1 D-isomer specific 2-hydroxyacid dehydrogenase family protein; Swiss-Prot: sp|Q65CJ7|HPPR_PLESU Hydroxyphenylpyruvate reductase; TrEMBL-Plants: tr|I1KGN9|I1KGN9_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0366700
Domains
13
LotjaGi3g1v0429500.1
– Glyoxylate reductase/hydroxypyruvate reductase; TAIR: AT2G45630.2 D-isomer specific 2-hydroxyacid dehydrogenase family protein; Swiss-Prot: sp|Q9LE33|HPR3_ARATH Glyoxylate/hydroxypyruvate reductase HPR3; TrEMBL-Plants: tr|A0A1J7I1B8|A0A1J7I1B8_LUPAN Uncharacterized protein; Found in the gene: LotjaGi3g1v0429500
Domains
13
LotjaGi3g1v0429700.1
– Glyoxylate reductase/hydroxypyruvate reductase; TAIR: AT2G45630.2 D-isomer specific 2-hydroxyacid dehydrogenase family protein; Swiss-Prot: sp|Q9LE33|HPR3_ARATH Glyoxylate/hydroxypyruvate reductase HPR3; TrEMBL-Plants: tr|A0A072TNE4|A0A072TNE4_MEDTR D-isomer specific 2-hydroxyacid dehydrogenase domain protein; Found in the gene: LotjaGi3g1v0429700
Domains
11
LotjaGi5g1v0327800.1
– D-3-phosphoglycerate dehydrogenase; TAIR: AT4G34200.1 D-3-phosphoglycerate dehydrogenase; Swiss-Prot: sp|O49485|SERA1_ARATH D-3-phosphoglycerate dehydrogenase 1, chloroplastic; TrEMBL-Plants: tr|I1LEI9|I1LEI9_SOYBN D-3-phosphoglycerate dehydrogenase; Found in the gene: LotjaGi5g1v0327800
Domains
29
LotjaGi5g1v0348300.1
– D-glycerate dehydrogenase/hydroxypyruvate reductase; TAIR: AT1G68010.1 hydroxypyruvate reductase; Swiss-Prot: sp|P13443|DHGY_CUCSA Glycerate dehydrogenase; TrEMBL-Plants: tr|I3S3H0|I3S3H0_LOTJA Uncharacterized protein; Found in the gene: LotjaGi5g1v0348300
Domains
13
LotjaGi5g1v0348300.2
– D-glycerate dehydrogenase/hydroxypyruvate reductase; TAIR: AT1G68010.3 hydroxypyruvate reductase; Swiss-Prot: sp|P13443|DHGY_CUCSA Glycerate dehydrogenase; TrEMBL-Plants: tr|I3S3H0|I3S3H0_LOTJA Uncharacterized protein; Found in the gene: LotjaGi5g1v0348300
Domains
13
LotjaGi5g1v0348300.3
– D-glycerate dehydrogenase/hydroxypyruvate reductase; TAIR: AT1G68010.3 hydroxypyruvate reductase; Swiss-Prot: sp|P13443|DHGY_CUCSA Glycerate dehydrogenase; TrEMBL-Plants: tr|I3S3H0|I3S3H0_LOTJA Uncharacterized protein; Found in the gene: LotjaGi5g1v0348300
Domains
13

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
cd05301 CDD 1 2.78