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PF08502

Source: Pfam

Description

LeuA allosteric (dimerisation) domain

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0003852
Molecular function 2-isopropylmalate synthase activity Catalysis of the reaction: 3-methyl-2-oxobutanoate + acetyl-CoA + H(2)O = (2S)-2-isopropylmalate + CoA + H(+).
Subterm of
GO:0009098
Biological process Leucine biosynthetic process The chemical reactions and pathways resulting in the formation of leucine, 2-amino-4-methylpentanoic acid.
Subterm of

Associated Lotus transcripts 10

Transcript Name Description Predicted domains Domain count
Lj1g3v3690020.1
– Homocitrate synthase [Lotus japonicus] gi|268607430|dbj|BAI49592.1|
Domains
16
Lj1g3v3690020.2
– Homocitrate synthase [Lotus japonicus] gi|268607430|dbj|BAI49592.1|
Domains
14
Lj1g3v3690180.1
– Homocitrate synthase [Lotus japonicus] gi|268607430|dbj|BAI49592.1|
Domains
19
Lj5g3v2298240.1
– PREDICTED: 2-isopropylmalate synthase 2, chloroplastic-like [Cicer arietinum] gi|502121886|ref|XP_004497478.1|
Domains
18
LotjaGi1g1v0613100.1
– 2-isopropylmalate synthase; TAIR: AT1G74040.1 2-isopropylmalate synthase 1; Swiss-Prot: sp|Q39891|LEU1_SOYBN Probable 2-isopropylmalate synthase; TrEMBL-Plants: tr|D0VY45|D0VY45_LOTJA Homocitrate synthase; Found in the gene: LotjaGi1g1v0613100
Domains
19
LotjaGi1g1v0613300.1
– 2-isopropylmalate synthase; TAIR: AT1G74040.1 2-isopropylmalate synthase 1; Swiss-Prot: sp|Q39891|LEU1_SOYBN Probable 2-isopropylmalate synthase; TrEMBL-Plants: tr|D0VY45|D0VY45_LOTJA Homocitrate synthase; Found in the gene: LotjaGi1g1v0613300
Domains
22
LotjaGi1g1v0613400.1
– 2-isopropylmalate synthase; TAIR: AT1G74040.1 2-isopropylmalate synthase 1; Swiss-Prot: sp|Q39891|LEU1_SOYBN Probable 2-isopropylmalate synthase; TrEMBL-Plants: tr|D0VY45|D0VY45_LOTJA Homocitrate synthase; Found in the gene: LotjaGi1g1v0613400
Domains
26
LotjaGi1g1v0613400.2
– 2-isopropylmalate synthase; TAIR: AT1G74040.1 2-isopropylmalate synthase 1; Swiss-Prot: sp|Q39891|LEU1_SOYBN Probable 2-isopropylmalate synthase; TrEMBL-Plants: tr|D0VY45|D0VY45_LOTJA Homocitrate synthase; Found in the gene: LotjaGi1g1v0613400
Domains
24
LotjaGi5g1v0362600.1
– 2-isopropylmalate synthase; TAIR: AT1G74040.1 2-isopropylmalate synthase 1; Swiss-Prot: sp|Q9C550|LEU12_ARATH 2-isopropylmalate synthase 2, chloroplastic; TrEMBL-Plants: tr|I1NJA5|I1NJA5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0362600
Domains
21
LotjaGi5g1v0362600.2
– 2-isopropylmalate synthase; TAIR: AT1G74040.1 2-isopropylmalate synthase 1; Swiss-Prot: sp|Q9C550|LEU12_ARATH 2-isopropylmalate synthase 2, chloroplastic; TrEMBL-Plants: tr|I1NJA5|I1NJA5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0362600
Domains
15

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
SSF51569 SUPERFAMILY 1 10.00