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PS00177

Description

DNA topoisomerase II signature.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
Molecular function DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
Molecular function DNA topoisomerase type II (ATP-hydrolyzing) activity Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2.
Molecular function ATP binding Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
Biological process DNA topological change The process in which a transformation is induced in the topological structure of a double-stranded DNA helix, resulting in a change in linking number.

Associated Lotus transcripts 8

Transcript Name Description Predicted domains Domain count
PREDICTED: DNA topoisomerase 2-like [Glycine max] gi|356555329|ref|XP_003545986.1| 35
PREDICTED: two-component response regulator-like APRR2-like isoform X1 [Cicer arietinum] gi|502152594|ref|XP_004508999.1| 21
DNA gyrase subunit B; TAIR: AT5G04130.1 DNA GYRASE B2; Swiss-Prot: sp|Q5YLB4|GYRB_NICBE DNA gyrase subunit B, chloroplastic/mitochondrial; TrEMBL-Plants: tr|A0A151TTM7|A0A151TTM7_CAJCA DNA gyrase subunit B; Found in the gene: LotjaGi1g1v0663600 41
DNA topoisomerase 2; TAIR: AT3G23890.1 topoisomerase II; Swiss-Prot: sp|O24308|TOP2_PEA DNA topoisomerase 2; TrEMBL-Plants: tr|I1MJQ7|I1MJQ7_SOYBN DNA topoisomerase 2; Found in the gene: LotjaGi3g1v0121000 45
DNA topoisomerase 2; TAIR: AT3G23890.2 topoisomerase II; Swiss-Prot: sp|O24308|TOP2_PEA DNA topoisomerase 2; TrEMBL-Plants: tr|I1MJQ7|I1MJQ7_SOYBN DNA topoisomerase 2; Found in the gene: LotjaGi3g1v0121000 45
Two-component response regulator-like protein; TAIR: AT4G18020.1 CheY-like two-component responsive regulator family protein; Swiss-Prot: sp|Q6LA43|APRR2_ARATH Two-component response regulator-like APRR2; TrEMBL-Plants: tr|A0A072V0B2|A0A072V0B2_MEDTR Two-component response regulator-APRR2-like protein; Found in the gene: LotjaGi4g1v0190400 22
Two-component response regulator-like protein; TAIR: AT4G18020.1 CheY-like two-component responsive regulator family protein; Swiss-Prot: sp|Q6LA43|APRR2_ARATH Two-component response regulator-like APRR2; TrEMBL-Plants: tr|A0A072UR72|A0A072UR72_MEDTR Two-component response regulator-APRR2-like protein; Found in the gene: LotjaGi4g1v0190400 22
Two-component response regulator-like protein; TAIR: AT4G18020.1 CheY-like two-component responsive regulator family protein; Swiss-Prot: sp|Q6LA43|APRR2_ARATH Two-component response regulator-like APRR2; TrEMBL-Plants: tr|A0A072UR72|A0A072UR72_MEDTR Two-component response regulator-APRR2-like protein; Found in the gene: LotjaGi4g1v0190400 22

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 12.50