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GO:0007094

View this GO term in other databases

Overview

Field Value
Namespace Biological process
Short description Mitotic spindle assembly checkpoint
Full defintion A cell cycle checkpoint that delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle.
Subterm of

Relationships

The relationship of GO:0007094 with other GO terms.

Relationship type GO terms
Is a
Regulates n.a.
Part of n.a.
Positively regulates n.a.
Negatively regulates n.a.

Ancestor tree

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Additional data

This table contains additional metadata associated with the GO entry's definition field.

Field Value
GOCmtg_cell_cycle
PMID
The spindle checkpoint: structural insights into dynamic signalling.Musacchio A, Hardwick KG
Nat Rev Mol Cell Biol. 2002 Oct; 3 (10): 731–41.PMID: 12360190

Chromosome segregation is a complex and astonishingly accurate process whose inner working is beginning to be understood at the molecular level. The spindle checkpoint plays a key role in ensuring the fidelity of this process. It monitors the interactions between chromosomes and microtubules, and delays mitotic progression to allow extra time to correct defects. Here, we review and integrate findings on the dynamics of checkpoint proteins at kinetochores with structural information about signalling complexes.

Associated Lotus transcripts 13

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

Transcript Name Description GO terms GO count
Lj0g3v0069309.1
– PREDICTED: mitotic checkpoint serine/threonine-protein kinase BUB1 beta-like [Glycine max] gi|356574353|ref|XP_003555313.1|
GO terms
1
Lj0g3v0073239.1
– PREDICTED: checkpoint serine/threonine-protein kinase BUB1-like [Glycine max] gi|356544986|ref|XP_003540927.1|
GO terms
1
Lj0g3v0087429.1
– PREDICTED: probable inactive serine/threonine-protein kinase bub1-like [Cicer arietinum] gi|502130042|ref|XP_004500510.1|
GO terms
1
Lj4g3v0002130.1
– PREDICTED: intracellular protein transport protein USO1-like isoform X2 [Cicer arietinum] gi|502126589|ref|XP_004499365.1|
GO terms
1
Lj4g3v0002130.2
– PREDICTED: intracellular protein transport protein USO1-like isoform X2 [Cicer arietinum] gi|502126589|ref|XP_004499365.1|
GO terms
1
LotjaGi2g1v0013500.1
– Mitotic spindle checkpoint protein bubr1; TAIR: AT2G33560.2 BUB1-related (BUB1: budding uninhibited by benzymidazol 1); Swiss-Prot: sp|O22806|BUBR1_ARATH Mitotic spindle checkpoint protein BUBR1; TrEMBL-Plants: tr|I1ND06|I1ND06_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0013500
GO terms
1
LotjaGi3g1v0452200.1
– Kinase family protein; TAIR: AT2G20635.1 protein kinase and Mad3-BUB1-I domain-containing protein; Swiss-Prot: sp|F4IVI0|BUB1_ARATH Mitotic checkpoint serine/threonine-protein kinase BUB1; TrEMBL-Plants: tr|K7LU99|K7LU99_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0452200
GO terms
1
LotjaGi4g1v0001500.1
– Mitotic spindle assembly checkpoint protein MAD1; TAIR: AT5G49880.1 mitotic checkpoint family protein; Swiss-Prot: sp|Q9LTY1|MAD1_ARATH Mitotic spindle checkpoint protein MAD1; TrEMBL-Plants: tr|A0A0B2P2M0|A0A0B2P2M0_GLYSO Mitotic spindle assembly checkpoint protein MAD1; Found in the gene: LotjaGi4g1v0001500
GO terms
1
LotjaGi6g1v0078400.1
– Mitotic spindle checkpoint protein bubr1; TAIR: AT5G05510.1 Mad3/BUB1 homology region 1; Swiss-Prot: sp|O22806|BUBR1_ARATH Mitotic spindle checkpoint protein BUBR1; TrEMBL-Plants: tr|K7LRS1|K7LRS1_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0078400
GO terms
1
LotjaGi6g1v0099800.1
– Mitotic spindle checkpoint protein MAD2; TAIR: AT3G25980.1 DNA-binding HORMA family protein; Swiss-Prot: sp|Q9LU93|MAD2_ARATH Mitotic spindle checkpoint protein MAD2; TrEMBL-Plants: tr|A0A151QV91|A0A151QV91_CAJCA Mitotic spindle checkpoint protein MAD2; Found in the gene: LotjaGi6g1v0099800
GO terms
1
LotjaGi6g1v0099800.2
– Mitotic spindle checkpoint protein MAD2; TAIR: AT3G25980.1 DNA-binding HORMA family protein; Swiss-Prot: sp|Q9LU93|MAD2_ARATH Mitotic spindle checkpoint protein MAD2; TrEMBL-Plants: tr|A0A151QV91|A0A151QV91_CAJCA Mitotic spindle checkpoint protein MAD2; Found in the gene: LotjaGi6g1v0099800
GO terms
1
LotjaGi6g1v0099800.3
– Mitotic spindle checkpoint protein MAD2; TAIR: AT3G25980.1 DNA-binding HORMA family protein; Swiss-Prot: sp|Q9LU93|MAD2_ARATH Mitotic spindle checkpoint protein MAD2; TrEMBL-Plants: tr|A0A151QV91|A0A151QV91_CAJCA Mitotic spindle checkpoint protein MAD2; Found in the gene: LotjaGi6g1v0099800
GO terms
1
LotjaGi6g1v0099800.4
– Mitotic spindle checkpoint protein MAD2; TAIR: AT3G25980.1 DNA-binding HORMA family protein; Swiss-Prot: sp|Q9LU93|MAD2_ARATH Mitotic spindle checkpoint protein MAD2; TrEMBL-Plants: tr|A0A151QV91|A0A151QV91_CAJCA Mitotic spindle checkpoint protein MAD2; Found in the gene: LotjaGi6g1v0099800
GO terms
1

Co-occuring GO terms 1

A list of co-occurring GO terms within the L. japonicus gene space:

GO term Namespace Name Observations Saturation (%)
GO:0007094
Biological process Mitotic spindle assembly checkpoint 1 7.69