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IPR000424 is a Primosome PriB/single-strand DNA-binding.
<p>The Escherichia coli single-strand binding protein [[cite:PUB00003606]] (gene ssb), also known as the helix-destabilising protein, is a protein of 177 amino acids. It binds tightly, as a homotetramer, to single-stranded DNA (ss-DNA) and plays an important role in DNA replication, recombination and repair. Closely related variants of SSB are encoded in the genome of a variety of large self-transmissible plasmids. SSB has also been characterized in bacteria such as Proteus mirabilis or Serratia marcescens. Eukaryotic mitochondrial proteins that bind ss-DNA and are probably involved in mitochondrial DNA replication are structurally and evolutionary related to prokaryotic SSB.</p> <p>Primosomal replication protein N (PriB) is a specialist protein from bacteria that binds single-stranded DNA at the primosome assembly site (PAS). The primosome is a mobile multiprotein replication priming complex which is believe to operate on the lagging-strand template at the E. coli DNA replication fork [[cite:PUB00054931]]. The primosome consists of one monomer of PriC and DnaT, two monomers of PriA, two dimers of PriB and one hexamer of DnaB [[cite:PUB00054930]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | Single-stranded DNA binding | Interacting selectively and non-covalently with single-stranded DNA. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: protein OSB2, chloroplastic-like [Cicer arietinum] gi|502115197|ref|XP_004495147.1| | 12 | ||
| – | PREDICTED: protein OSB1, mitochondrial-like [Glycine max] gi|356553917|ref|XP_003545297.1| | 9 | ||
| – | PREDICTED: protein OSB2, chloroplastic-like [Cicer arietinum] gi|502164271|ref|XP_004513105.1| | 9 | ||
| – | PREDICTED: single-stranded DNA-binding protein, mitochondrial-like [Cicer arietinum] gi|502122587|ref|XP_004497818.1| | 12 | ||
| – | PREDICTED: protein OSB2, chloroplastic-like [Cicer arietinum] gi|502164271|ref|XP_004513105.1| | 9 | ||
| – | PREDICTED: protein OSB2, chloroplastic-like [Cicer arietinum] gi|502115197|ref|XP_004495147.1| | 12 | ||
| – | Protein OSB3, chloroplastic/mitochondrial; TAIR: AT5G44785.2 organellar single-stranded DNA binding protein 3; Swiss-Prot: sp|Q8GWJ4|OSB3_ARATH Protein OSB3, chloroplastic/mitochondrial; TrEMBL-Plants: tr|A0A0L9VGU0|A0A0L9VGU0_PHAAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0233700 | 8 | ||
| – | Single-stranded DNA-binding protein; TAIR: AT3G18580.1 Nucleic acid-binding, OB-fold-like protein; Swiss-Prot: sp|Q84J78|SSBP_ARATH Single-stranded DNA-binding protein, mitochondrial; TrEMBL-Plants: tr|V7CAJ9|V7CAJ9_PHAVU Uncharacterized protein; Found in the gene: LotjaGi4g1v0262500 | 12 | ||
| – | Protein OSB1, mitochondrial; TAIR: AT1G47720.1 Primosome PriB/single-strand DNA-binding protein; Swiss-Prot: sp|Q9SX99|OSB1_ARATH Protein OSB1, mitochondrial; TrEMBL-Plants: tr|A0A151RMN9|A0A151RMN9_CAJCA Uncharacterized protein; Found in the gene: LotjaGi5g1v0023300 | 10 | ||
| – | Protein OSB1, mitochondrial; TAIR: AT1G47720.1 Primosome PriB/single-strand DNA-binding protein; Swiss-Prot: sp|Q9SX99|OSB1_ARATH Protein OSB1, mitochondrial; TrEMBL-Plants: tr|A0A151RMN9|A0A151RMN9_CAJCA Uncharacterized protein; Found in the gene: LotjaGi5g1v0023300 | 10 | ||
| – | Single-stranded DNA-binding protein; TAIR: AT4G20010.2 plastid transcriptionally active 9; Swiss-Prot: sp|Q8GXH3|OSB2_ARATH Protein OSB2, chloroplastic; TrEMBL-Plants: tr|A0A0R0KWQ4|A0A0R0KWQ4_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0174600 | 11 | ||
| – | Single-stranded DNA-binding protein; TAIR: AT1G47720.1 Primosome PriB/single-strand DNA-binding protein; Swiss-Prot: sp|Q9SX99|OSB1_ARATH Protein OSB1, mitochondrial; TrEMBL-Plants: tr|I1JF51|I1JF51_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0174600 | 11 | ||
| – | Single-stranded DNA-binding protein; TAIR: AT4G11060.1 mitochondrially targeted single-stranded DNA binding protein; Swiss-Prot: sp|Q84J78|SSBP_ARATH Single-stranded DNA-binding protein, mitochondrial; TrEMBL-Plants: tr|I3SK50|I3SK50_LOTJA Uncharacterized protein; Found in the gene: LotjaGi5g1v0227500 | 11 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 7.69 |