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IPR003349 is a JmjN domain.
<p>This entry represents the JmjN domain.</p> <p>The JmjN and JmjC domains are two non-adjacent domains which have been identified in the jumonji family of transcription factors. Although it was originally suggested that the JmjN and JmjC domains always co-occur and might form a single functional unit within the folded protein, the JmjC domain was later found without the JmjN domain in organisms from bacteria to human [[cite:PUB00008126], [cite:PUB00007419]].</p> <p>JmJC domains are predicted to be metalloenzymes that adopt the cupin fold, and are candidates for enzymes that regulate chromatin remodelling. The cupin fold is a flattened β-barrel structure containing two sheets of five antiparallel β-strands that form the walls of a zinc-binding cleft. JmjC domains were identified in numerous eukaryotic proteins containing domains typical of transcription factors, such as PHD, C2H2, ARID/BRIGHT and zinc fingers [[cite:PUB00007419], [cite:PUB00021723]]. The JmjC has been shown to function in a histone demethylation mechanism that is conserved from yeast to human [[cite:PUB00033727]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: probable lysine-specific demethylase ELF6-like [Glycine max] gi|356533957|ref|XP_003535524.1| | 20 | ||
| – | PREDICTED: lysine-specific demethylase 5D-like [Glycine max] gi|356530249|ref|XP_003533695.1| | 11 | ||
| – | PREDICTED: lysine-specific demethylase REF6-like [Glycine max] gi|356518921|ref|XP_003528124.1| | 20 | ||
| – | PREDICTED: probable lysine-specific demethylase JMJ14-like isoform X1 [Cicer arietinum] gi|502110041|ref|XP_004493785.1| | 14 | ||
| – | PREDICTED: lysine-specific demethylase 5C-like [Glycine max] gi|356531447|ref|XP_003534289.1| | 15 | ||
| – | Lysine-specific demethylase 5D [Medicago truncatula] gi|357481617|ref|XP_003611094.1| | 35 | ||
| – | PREDICTED: lysine-specific demethylase REF6-like [Cicer arietinum] gi|502176308|ref|XP_004515844.1| | 20 | ||
| – | PREDICTED: probable lysine-specific demethylase JMJ14-like [Glycine max] gi|356574834|ref|XP_003555549.1| | 22 | ||
| – | PREDICTED: probable lysine-specific demethylase ELF6-like [Cicer arietinum] gi|502118416|ref|XP_004496256.1| | 12 | ||
| – | Zinc finger protein; TAIR: AT3G48430.1 relative of early flowering 6; Swiss-Prot: sp|Q9STM3|REF6_ARATH Lysine-specific demethylase REF6; TrEMBL-Plants: tr|I1JXF4|I1JXF4_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0231500 | 20 | ||
| – | Lysine-specific demethylase; TAIR: AT1G08620.1 Transcription factor jumonji (jmj) family protein / zinc finger (C5HC2 type) family protein; Swiss-Prot: sp|Q53WJ1|JM703_ORYSJ Lysine-specific demethylase JMJ703; TrEMBL-Plants: tr|K7MYQ0|K7MYQ0_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0707900 | 14 | ||
| – | Lysine-specific demethylase; TAIR: AT5G46910.1 Transcription factor jumonji (jmj) family protein / zinc finger (C5HC2 type) family protein; Swiss-Prot: sp|Q336N8|JM706_ORYSJ Lysine-specific demethylase JMJ706; TrEMBL-Plants: tr|K7LKB6|K7LKB6_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0021700 | 13 | ||
| – | Lysine-specific demethylase; TAIR: AT5G46910.1 Transcription factor jumonji (jmj) family protein / zinc finger (C5HC2 type) family protein; Swiss-Prot: sp|Q336N8|JM706_ORYSJ Lysine-specific demethylase JMJ706; TrEMBL-Plants: tr|A0A0B2RWY9|A0A0B2RWY9_GLYSO Lysine-specific demethylase REF6; Found in the gene: LotjaGi2g1v0336400 | 16 | ||
| – | Lysine-specific demethylase; TAIR: AT1G63490.4 transcription factor jumonji (jmjC) domain-containing protein; Swiss-Prot: sp|P29375|KDM5A_HUMAN Lysine-specific demethylase 5A; TrEMBL-Plants: tr|K7LMP3|K7LMP3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0433900 | 40 | ||
| – | Lysine-specific demethylase; TAIR: AT1G63490.4 transcription factor jumonji (jmjC) domain-containing protein; Swiss-Prot: sp|P29375|KDM5A_HUMAN Lysine-specific demethylase 5A; TrEMBL-Plants: tr|K7LMP3|K7LMP3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0433900 | 41 | ||
| – | Lysine-specific demethylase; TAIR: AT5G46910.1 Transcription factor jumonji (jmj) family protein / zinc finger (C5HC2 type) family protein; Swiss-Prot: sp|Q336N8|JM706_ORYSJ Lysine-specific demethylase JMJ706; TrEMBL-Plants: tr|I1L793|I1L793_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0530600 | 16 | ||
| – | Zinc finger protein; TAIR: AT3G48430.1 relative of early flowering 6; Swiss-Prot: sp|Q9STM3|REF6_ARATH Lysine-specific demethylase REF6; TrEMBL-Plants: tr|A0A0S3R676|A0A0S3R676_PHAAN Uncharacterized protein; Found in the gene: LotjaGi4g1v0225200 | 20 | ||
| – | Lysine-specific demethylase; TAIR: AT1G08620.1 Transcription factor jumonji (jmj) family protein / zinc finger (C5HC2 type) family protein; Swiss-Prot: sp|C0SUT9|JMJ16_ARATH Putative lysine-specific demethylase JMJ16; TrEMBL-Plants: tr|K7N4Y4|K7N4Y4_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0201800 | 23 | ||
| – | Lysine-specific demethylase; TAIR: AT4G20400.1 JUMONJI 14; Swiss-Prot: sp|Q8GUI6|JMJ14_ARATH Probable lysine-specific demethylase JMJ14; TrEMBL-Plants: tr|K7LCJ5|K7LCJ5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0214500 | 25 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 5.26 |