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IPR004342

Description

IPR004342 is a EXS, C-terminal.

<p>The EXS domain is named after ERD1/XPR1/SYG1 and proteins containing this motif include the C-terminal of the SYG1 G-protein associated signal transduction protein from Saccharomyces cerevisiae, and sequences that are thought to be Murine leukemia virus (MLV) receptors (XPR1. The N-terminal of these proteins often have an SPX domain ([interpro:IPR004331]) [[cite:PUB00007516]].</p> <p>While the N-terminal is thought to be involved in signal transduction, the role of the C-terminal is not known. This region of similarity contains several predicted transmembrane helices. This family also includes the ERD1 (ERD: ER retention defective) S. cerevisiae proteins. ERD1 proteins are involved in the localization of endogenous endoplasmic reticulum (ER) proteins. Erd1 null mutants secrete such proteins even though they possess the C-terminal HDEL ER lumen localization label sequence. In addition, null mutants also exhibit defects in the Golgi-dependent processing of several glycoproteins, which led to the suggestion that the sorting of luminal ER proteins actually occurs in the Golgi, with subsequent return of these proteins to the ER via `salvage' vesicles [[cite:PUB00007533]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
Cellular component Integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

Associated Lotus transcripts 31

Transcript Name Description Predicted domains Domain count
PREDICTED: SPX and EXS domain-containing protein 1-like [Glycine max] gi|356530102|ref|XP_003533623.1| 8
PREDICTED: SPX and EXS domain-containing protein 1-like [Glycine max] gi|356568338|ref|XP_003552368.1| 8
PREDICTED: SPX and EXS domain-containing protein 1-like [Glycine max] gi|356568338|ref|XP_003552368.1| 8
PREDICTED: phosphate transporter PHO1 homolog 9-like [Glycine max] gi|356568688|ref|XP_003552542.1| 15
PREDICTED: phosphate transporter PHO1 homolog 9-like [Glycine max] gi|356568688|ref|XP_003552542.1| 15
PREDICTED: phosphate transporter PHO1 homolog 1-like isoform 1 [Glycine max] gi|356496020|ref|XP_003516868.1| 13
PREDICTED: phosphate transporter PHO1 homolog 1-like isoform 1 [Glycine max] gi|356496020|ref|XP_003516868.1| 14
PREDICTED: phosphate transporter PHO1 homolog 10-like [Glycine max] gi|356502567|ref|XP_003520090.1| 13
Xenotropic and polytropic retrovirus receptor-like protein [Medicago truncatula] gi|357487187|ref|XP_003613881.1| 8
PREDICTED: SPX and EXS domain-containing protein 1-like [Cicer arietinum] gi|502083148|ref|XP_004487374.1| 10
PREDICTED: SPX and EXS domain-containing protein 1-like [Cicer arietinum] gi|502083148|ref|XP_004487374.1| 10
PREDICTED: phosphate transporter PHO1 homolog 1-like isoform 1 [Glycine max] gi|356500006|ref|XP_003518826.1| 12
PREDICTED: phosphate transporter PHO1 homolog 1-like isoform 1 [Glycine max] gi|356500006|ref|XP_003518826.1| 12
PREDICTED: phosphate transporter PHO1-like [Glycine max] gi|356535386|ref|XP_003536227.1| 13
PREDICTED: phosphate transporter PHO1-like [Glycine max] gi|356535386|ref|XP_003536227.1| 14
Pho1-like protein [Medicago truncatula] gi|357452341|ref|XP_003596447.1| 14
SPX and EXS domain-containing protein 1; TAIR: AT5G35730.1 EXS (ERD1/XPR1/SYG1) family protein; Swiss-Prot: sp|Q55B06|SPXS1_DICDI SPX and EXS domain-containing protein 1; TrEMBL-Plants: tr|V7B265|V7B265_PHAVU Uncharacterized protein; Found in the gene: LotjaGi1g1v0470100 9
SPX and EXS domain-containing protein 1; TAIR: AT5G35730.1 EXS (ERD1/XPR1/SYG1) family protein; Swiss-Prot: sp|Q55B06|SPXS1_DICDI SPX and EXS domain-containing protein 1; TrEMBL-Plants: tr|V7B265|V7B265_PHAVU Uncharacterized protein; Found in the gene: LotjaGi1g1v0470100 9
SPX and EXS domain-containing protein 1; TAIR: AT5G35730.1 EXS (ERD1/XPR1/SYG1) family protein; Swiss-Prot: sp|Q55B06|SPXS1_DICDI SPX and EXS domain-containing protein 1; TrEMBL-Plants: tr|V7B265|V7B265_PHAVU Uncharacterized protein; Found in the gene: LotjaGi1g1v0470100 14
Phosphate transporter PHO1-like protein; TAIR: AT3G29060.1 EXS (ERD1/XPR1/SYG1) family protein; Swiss-Prot: sp|Q9LJW0|PHO19_ARATH Phosphate transporter PHO1 homolog 9; TrEMBL-Plants: tr|A0A151TCA7|A0A151TCA7_CAJCA Putative phosphate transporter 1; Found in the gene: LotjaGi1g1v0505800 16
Phosphate transporter PHO1-like protein; TAIR: AT1G68740.1 EXS (ERD1/XPR1/SYG1) family protein; Swiss-Prot: sp|Q93ZF5|PHO11_ARATH Phosphate transporter PHO1 homolog 1; TrEMBL-Plants: tr|I1J6T3|I1J6T3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0284100 15
Phosphate transporter PHO1-like protein; TAIR: AT1G68740.1 EXS (ERD1/XPR1/SYG1) family protein; Swiss-Prot: sp|Q93ZF5|PHO11_ARATH Phosphate transporter PHO1 homolog 1; TrEMBL-Plants: tr|I1J6T3|I1J6T3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0284100 15
Phosphate transporter PHO1-like protein; TAIR: AT1G69480.1 EXS (ERD1/XPR1/SYG1) family protein; Swiss-Prot: sp|Q6R8G0|PHO1A_ARATH Phosphate transporter PHO1 homolog 10; TrEMBL-Plants: tr|G7JWG7|G7JWG7_MEDTR Phosphate transporter PHO1-like protein; Found in the gene: LotjaGi2g1v0300900 15
Phosphate transporter PHO1-like protein; TAIR: AT1G69480.1 EXS (ERD1/XPR1/SYG1) family protein; Swiss-Prot: sp|Q6R8G0|PHO1A_ARATH Phosphate transporter PHO1 homolog 10; TrEMBL-Plants: tr|G7JWG7|G7JWG7_MEDTR Phosphate transporter PHO1-like protein; Found in the gene: LotjaGi2g1v0300900 15
SPX and EXS domain-containing protein 1; TAIR: AT5G35730.1 EXS (ERD1/XPR1/SYG1) family protein; Swiss-Prot: sp|Q55B06|SPXS1_DICDI SPX and EXS domain-containing protein 1; TrEMBL-Plants: tr|I3T4H0|I3T4H0_LOTJA Uncharacterized protein; Found in the gene: LotjaGi3g1v0191600 10
Phosphate transporter PHO1-like protein; TAIR: AT1G68740.1 EXS (ERD1/XPR1/SYG1) family protein; Swiss-Prot: sp|Q93ZF5|PHO11_ARATH Phosphate transporter PHO1 homolog 1; TrEMBL-Plants: tr|A0A1J7HP60|A0A1J7HP60_LUPAN Uncharacterized protein; Found in the gene: LotjaGi4g1v0152100 16
Phosphate transporter PHO1 like 1; TAIR: AT1G68740.1 EXS (ERD1/XPR1/SYG1) family protein; Swiss-Prot: sp|Q93ZF5|PHO11_ARATH Phosphate transporter PHO1 homolog 1; TrEMBL-Plants: tr|A0A1J7HP60|A0A1J7HP60_LUPAN Uncharacterized protein; Found in the gene: LotjaGi4g1v0152100 16
Phosphate transporter PHO1-like protein; TAIR: AT1G68740.1 EXS (ERD1/XPR1/SYG1) family protein; Swiss-Prot: sp|Q93ZF5|PHO11_ARATH Phosphate transporter PHO1 homolog 1; TrEMBL-Plants: tr|A0A1J7HP60|A0A1J7HP60_LUPAN Uncharacterized protein; Found in the gene: LotjaGi4g1v0152100 16
Phosphate transporter PHO1; TAIR: AT3G23430.1 phosphate 1; Swiss-Prot: sp|Q8S403|PHO1_ARATH Phosphate transporter PHO1; TrEMBL-Plants: tr|A0A151U5X3|A0A151U5X3_CAJCA Putative phosphate transporter 1; Found in the gene: LotjaGi5g1v0188800 15
Phosphate transporter PHO1; TAIR: AT3G23430.1 phosphate 1; Swiss-Prot: sp|Q8S403|PHO1_ARATH Phosphate transporter PHO1; TrEMBL-Plants: tr|A0A151U5X3|A0A151U5X3_CAJCA Putative phosphate transporter 1; Found in the gene: LotjaGi5g1v0188800 15
Phosphate transporter PHO1-like protein; TAIR: AT3G23430.1 phosphate 1; Swiss-Prot: sp|Q8S403|PHO1_ARATH Phosphate transporter PHO1; TrEMBL-Plants: tr|A0A072VHJ2|A0A072VHJ2_MEDTR Phosphate transporter PHO1-like protein; Found in the gene: LotjaGi6g1v0003600 15

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 3.23