Your browser is unable to support new features implemented in HTML5 and CSS3 to render this site as intended. Your experience may suffer from functionality degradation but the site should remain usable. We strongly recommend the latest version of Google Chrome, OS X Safari or Mozilla Firefox. As Safari is bundled with OS X, if you are unable to upgrade to a newer version of OS X, we recommend using an open source browser. Dismiss message
IPR011947 is a FCP1-like phosphatase, phosphatase domain.
<p>This entry represents the phosphatase domain of the human RNA polymerase II subunit A C-terminal domain phosphatase (FCP1, [[cite:PUB00015516]]) and closely related phosphatases from eukaryotes including plants, fungi [[cite:PUB00015517]] and slime mold. This domain is a member of the haloacid dehalogenase (HAD) superfamily by virtue of a conserved set of three catalytic motifs [[cite:PUB00003337]] and a conserved fold as predicted by PSIPRED. The third motif in this family is distinctive (hhhhDDppphW). This domain is classified as a "Class III" HAD, since there is no large "cap" domain found between motifs 1 and 2 or motifs 2 and 3 [[cite:PUB00009589]]. This domain is related to domains found in the human NLI interacting factor-like phosphatases.</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | Phosphoprotein phosphatase activity | Catalysis of the reaction: a phosphoprotein + H2O = a protein + phosphate. Together with protein kinases, these enzymes control the state of phosphorylation of cell proteins and thereby provide an important mechanism for regulating cellular activity. | ||
| Cellular component | Nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: RNA polymerase II C-terminal domain phosphatase-like 4-like [Glycine max] gi|356498756|ref|XP_003518215.1| | 10 | ||
| – | PREDICTED: RNA polymerase II C-terminal domain phosphatase-like 4-like [Glycine max] gi|356498756|ref|XP_003518215.1| | 10 | ||
| – | PREDICTED: RNA polymerase II C-terminal domain phosphatase-like 3-like [Glycine max] gi|356523718|ref|XP_003530482.1| | 19 | ||
| – | PREDICTED: RNA polymerase II C-terminal domain phosphatase-like 4-like isoform X1 [Cicer arietinum] gi|502149960|ref|XP_004507725.1| | 11 | ||
| – | PREDICTED: RNA polymerase II C-terminal domain phosphatase-like 4-like [Glycine max] gi|356564913|ref|XP_003550691.1| | 11 | ||
| – | RNA polymerase II C-terminal domain phosphatase-like protein; TAIR: AT2G33540.1 C-terminal domain phosphatase-like 3; Swiss-Prot: sp|Q8LL04|CPL3_ARATH RNA polymerase II C-terminal domain phosphatase-like 3; TrEMBL-Plants: tr|I1KWR8|I1KWR8_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0529200 | 24 | ||
| – | RNA polymerase II C-terminal domain phosphatase-like protein; TAIR: AT5G58003.1 C-terminal domain phosphatase-like 4; Swiss-Prot: sp|Q00IB6|CPL4_ARATH RNA polymerase II C-terminal domain phosphatase-like 4; TrEMBL-Plants: tr|A0A072UR90|A0A072UR90_MEDTR Carboxy-terminal domain phosphatase-like protein; Found in the gene: LotjaGi1g1v0661000 | 14 | ||
| – | RNA polymerase II C-terminal domain phosphatase-like protein; TAIR: AT5G58003.3 C-terminal domain phosphatase-like 4; Swiss-Prot: sp|Q00IB6|CPL4_ARATH RNA polymerase II C-terminal domain phosphatase-like 4; TrEMBL-Plants: tr|A0A151SFP9|A0A151SFP9_CAJCA Uncharacterized protein; Found in the gene: LotjaGi4g1v0286500 | 14 | ||
| – | RNA polymerase II C-terminal domain phosphatase-like protein; TAIR: AT5G58003.1 C-terminal domain phosphatase-like 4; Swiss-Prot: sp|Q00IB6|CPL4_ARATH RNA polymerase II C-terminal domain phosphatase-like 4; TrEMBL-Plants: tr|V7BX02|V7BX02_PHAVU Uncharacterized protein; Found in the gene: LotjaGi4g1v0287100 | 23 | ||
| – | RNA polymerase II C-terminal domain phosphatase-like protein; TAIR: AT5G58003.1 C-terminal domain phosphatase-like 4; Swiss-Prot: sp|Q00IB6|CPL4_ARATH RNA polymerase II C-terminal domain phosphatase-like 4; TrEMBL-Plants: tr|A0A0L9TRV4|A0A0L9TRV4_PHAAN Uncharacterized protein; Found in the gene: LotjaGi4g1v0287100 | 22 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| cd17729 | CDD | 1 | 10.00 |