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IPR004274 is a FCP1 homology domain.
<p>Yeast FCP1 is an essential protein serine phosphatase ([ec:3.1.3.16]) that dephosphorylates the C-terminal domain (CTD) of RNA polymerase II. FCP1 orthologs are present in all known eukaryote proteomes. The N-terminal domain of FCP1 corresponds to the catalytic unit of the phosphatase and has been refered to as the FCP1 homology domain. The FCP1 homology domain, which is a ~180-residue module, is also found in many other proteins of unknown function. It contains a DxDx(T/V) motif preceded by four hydrophobic residues characteristic of a large family of metal-dependent phosphohydrolases and phosphotransferases. The first aspartate residue is likely to participate in catalysis, whereas the second could have a role in substrate recognition [[cite:PUB00018438], [cite:PUB00018439], [cite:PUB00018440], [cite:PUB00018441]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | CTD small phosphatase-like protein [Medicago truncatula] gi|357492701|ref|XP_003616639.1| | 13 | ||
| – | PREDICTED: CTD small phosphatase-like protein 2-like isoform X1 [Cicer arietinum] gi|502127193|ref|XP_004499597.1| | 11 | ||
| – | PREDICTED: RNA polymerase II C-terminal domain phosphatase-like 4-like [Glycine max] gi|356498756|ref|XP_003518215.1| | 10 | ||
| – | PREDICTED: RNA polymerase II C-terminal domain phosphatase-like 4-like [Glycine max] gi|356498756|ref|XP_003518215.1| | 10 | ||
| – | PREDICTED: probable C-terminal domain small phosphatase-like isoform X4 [Cicer arietinum] gi|502170470|ref|XP_004514839.1| | 9 | ||
| – | PREDICTED: probable C-terminal domain small phosphatase-like isoform X1 [Cicer arietinum] gi|502170457|ref|XP_004514836.1| | 8 | ||
| – | PREDICTED: RNA polymerase II C-terminal domain phosphatase-like 2-like [Glycine max] gi|356521002|ref|XP_003529147.1| | 17 | ||
| – | PREDICTED: RNA polymerase II C-terminal domain phosphatase-like 2-like [Glycine max] gi|356521002|ref|XP_003529147.1| | 17 | ||
| – | PREDICTED: probable C-terminal domain small phosphatase-like isoform X4 [Cicer arietinum] gi|502170470|ref|XP_004514839.1| | 9 | ||
| – | PREDICTED: probable C-terminal domain small phosphatase-like isoform X4 [Cicer arietinum] gi|502170470|ref|XP_004514839.1| | 9 | ||
| – | PREDICTED: RNA polymerase II C-terminal domain phosphatase-like 3-like [Glycine max] gi|356523718|ref|XP_003530482.1| | 19 | ||
| – | PREDICTED: RNA polymerase II C-terminal domain phosphatase-like 4-like [Glycine max] gi|356498756|ref|XP_003518215.1| | 9 | ||
| – | PREDICTED: RNA polymerase II C-terminal domain phosphatase-like 4-like isoform X3 [Cicer arietinum] gi|502149964|ref|XP_004507727.1| | 9 | ||
| – | PREDICTED: probable C-terminal domain small phosphatase-like isoform X3 [Cicer arietinum] gi|502170466|ref|XP_004514838.1| | 9 | ||
| – | PREDICTED: probable C-terminal domain small phosphatase-like isoform X4 [Cicer arietinum] gi|502170470|ref|XP_004514839.1| | 9 | ||
| – | CTD small phosphatase-like protein [Medicago truncatula] gi|357492701|ref|XP_003616639.1| | 15 | ||
| – | PREDICTED: mitochondrial import inner membrane translocase subunit TIM50-like [Glycine max] gi|356552618|ref|XP_003544661.1| | 17 | ||
| – | PREDICTED: CTD small phosphatase-like protein 2-like isoform X1 [Cicer arietinum] gi|502127193|ref|XP_004499597.1| | 12 | ||
| – | PREDICTED: CTD small phosphatase-like protein 2-like isoform X1 [Cicer arietinum] gi|502127193|ref|XP_004499597.1| | 12 | ||
| – | PREDICTED: RNA polymerase II C-terminal domain phosphatase-like 1-like [Glycine max] gi|356521333|ref|XP_003529311.1| | 17 | ||
| – | PREDICTED: RNA polymerase II C-terminal domain phosphatase-like 1-like [Glycine max] gi|356521333|ref|XP_003529311.1| | 17 | ||
| – | PREDICTED: RNA polymerase II C-terminal domain phosphatase-like 4-like isoform X1 [Cicer arietinum] gi|502149960|ref|XP_004507725.1| | 11 | ||
| – | PREDICTED: RNA polymerase II C-terminal domain phosphatase-like 4-like [Glycine max] gi|356564913|ref|XP_003550691.1| | 11 | ||
| – | Uncharacterized protein isoform 1 [Theobroma cacao] gi|508774843|gb|EOY22099.1| | 10 | ||
| – | Uncharacterized protein isoform 3 [Theobroma cacao] gi|508774845|gb|EOY22101.1| | 9 | ||
| – | Uncharacterized protein isoform 1 [Theobroma cacao] gi|508774843|gb|EOY22099.1| | 10 | ||
| – | Uncharacterized protein isoform 1 [Theobroma cacao] gi|508774843|gb|EOY22099.1| | 10 | ||
| – | PREDICTED: CTD small phosphatase-like protein 2-like isoform X1 [Cicer arietinum] gi|502086585|ref|XP_004488263.1| | 11 | ||
| – | PREDICTED: ubiquitin-like domain-containing CTD phosphatase-like [Glycine max] gi|356525365|ref|XP_003531295.1| | 19 | ||
| – | PREDICTED: CTD small phosphatase-like protein 2-like isoform X1 [Cicer arietinum] gi|502086585|ref|XP_004488263.1| | 11 | ||
| – | PREDICTED: probable C-terminal domain small phosphatase-like isoform X1 [Cicer arietinum] gi|502078420|ref|XP_004485939.1| | 15 | ||
| – | Mitochondrial import inner membrane translocase subunit TIM50; TAIR: AT1G55900.1 Haloacid dehalogenase-like hydrolase (HAD) superfamily protein; Swiss-Prot: sp|Q8VYE2|TIM50_ARATH Mitochondrial import inner membrane translocase subunit TIM50; TrEMBL-Plants: tr|V7B9A1|V7B9A1_PHAVU Uncharacterized protein; Found in the gene: LotjaGi1g1v0017100 | 19 | ||
| – | CTD small phosphatase-like protein; TAIR: AT3G55960.1 Haloacid dehalogenase-like hydrolase (HAD) superfamily protein; Swiss-Prot: sp|O15194|CTDSL_HUMAN CTD small phosphatase-like protein; TrEMBL-Plants: tr|A0A151R002|A0A151R002_CAJCA Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1; Found in the gene: LotjaGi1g1v0077300 | 17 | ||
| – | CTD small phosphatase-like protein; TAIR: AT3G55960.1 Haloacid dehalogenase-like hydrolase (HAD) superfamily protein; Swiss-Prot: sp|Q54GB2|CTSL2_DICDI CTD small phosphatase-like protein 2; TrEMBL-Plants: tr|A0A151R002|A0A151R002_CAJCA Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1; Found in the gene: LotjaGi1g1v0077300 | 17 | ||
| – | Haloacid dehalogenase-like hydrolase (HAD) superfamily protein; TAIR: AT3G29760.3 Haloacid dehalogenase-like hydrolase (HAD) superfamily protein; Swiss-Prot: sp|O94336|YHM3_SCHPO Uncharacterized FCP1 homology domain-containing protein C1271.03c; TrEMBL-Plants: tr|V7B1L6|V7B1L6_PHAVU Uncharacterized protein; Found in the gene: LotjaGi1g1v0197700 | 11 | ||
| – | Haloacid dehalogenase-like hydrolase (HAD) superfamily protein; TAIR: AT3G29760.3 Haloacid dehalogenase-like hydrolase (HAD) superfamily protein; Swiss-Prot: sp|O94336|YHM3_SCHPO Uncharacterized FCP1 homology domain-containing protein C1271.03c; TrEMBL-Plants: tr|A0A0L9UB26|A0A0L9UB26_PHAAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0212400_LC | 12 | ||
| – | Haloacid dehalogenase-like hydrolase (HAD) superfamily protein; TAIR: AT3G29760.3 Haloacid dehalogenase-like hydrolase (HAD) superfamily protein; Swiss-Prot: sp|O94336|YHM3_SCHPO Uncharacterized FCP1 homology domain-containing protein C1271.03c; TrEMBL-Plants: tr|A0A0L9UB26|A0A0L9UB26_PHAAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0212400_LC | 12 | ||
| – | Haloacid dehalogenase-like hydrolase (HAD) superfamily protein; TAIR: AT3G29760.3 Haloacid dehalogenase-like hydrolase (HAD) superfamily protein; Swiss-Prot: sp|O94336|YHM3_SCHPO Uncharacterized FCP1 homology domain-containing protein C1271.03c; TrEMBL-Plants: tr|A0A0L9UB26|A0A0L9UB26_PHAAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0212400_LC | 12 | ||
| – | Haloacid dehalogenase-like hydrolase (HAD) superfamily protein; TAIR: AT3G29760.3 Haloacid dehalogenase-like hydrolase (HAD) superfamily protein; Swiss-Prot: sp|O94336|YHM3_SCHPO Uncharacterized FCP1 homology domain-containing protein C1271.03c; TrEMBL-Plants: tr|A0A0L9UB26|A0A0L9UB26_PHAAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0212400_LC | 12 | ||
| – | Haloacid dehalogenase-like hydrolase (HAD) superfamily protein; TAIR: AT3G29760.3 Haloacid dehalogenase-like hydrolase (HAD) superfamily protein; Swiss-Prot: sp|O94336|YHM3_SCHPO Uncharacterized FCP1 homology domain-containing protein C1271.03c; TrEMBL-Plants: tr|A0A0L9UB26|A0A0L9UB26_PHAAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0212400_LC | 12 | ||
| – | Haloacid dehalogenase-like hydrolase (HAD) superfamily protein; TAIR: AT3G29760.3 Haloacid dehalogenase-like hydrolase (HAD) superfamily protein; Swiss-Prot: sp|O94336|YHM3_SCHPO Uncharacterized FCP1 homology domain-containing protein C1271.03c; TrEMBL-Plants: tr|A0A0L9UB26|A0A0L9UB26_PHAAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0212400_LC | 12 | ||
| – | RNA polymerase II C-terminal domain phosphatase-like 2; TAIR: AT5G01270.1 carboxyl-terminal domain (ctd) phosphatase-like 2; Swiss-Prot: sp|Q5YDB5|CPL2_ARATH RNA polymerase II C-terminal domain phosphatase-like 2; TrEMBL-Plants: tr|K7L1T3|K7L1T3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0439500 | 18 | ||
| – | Haloacid dehalogenase-like hydrolase (HAD) superfamily protein; TAIR: AT3G29760.3 Haloacid dehalogenase-like hydrolase (HAD) superfamily protein; Swiss-Prot: sp|O94336|YHM3_SCHPO Uncharacterized FCP1 homology domain-containing protein C1271.03c; TrEMBL-Plants: tr|A0A151RYH2|A0A151RYH2_CAJCA Putative FCP1 isogenyy domain-containing protein C1271.03c family; Found in the gene: LotjaGi1g1v0514700 | 10 | ||
| – | RNA polymerase II C-terminal domain phosphatase-like protein; TAIR: AT2G33540.1 C-terminal domain phosphatase-like 3; Swiss-Prot: sp|Q8LL04|CPL3_ARATH RNA polymerase II C-terminal domain phosphatase-like 3; TrEMBL-Plants: tr|I1KWR8|I1KWR8_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0529200 | 24 | ||
| – | RNA polymerase II C-terminal domain phosphatase-like protein; TAIR: AT5G58003.1 C-terminal domain phosphatase-like 4; Swiss-Prot: sp|Q00IB6|CPL4_ARATH RNA polymerase II C-terminal domain phosphatase-like 4; TrEMBL-Plants: tr|A0A072UR90|A0A072UR90_MEDTR Carboxy-terminal domain phosphatase-like protein; Found in the gene: LotjaGi1g1v0661000 | 14 | ||
| – | Haloacid dehalogenase-like hydrolase (HAD) superfamily protein; TAIR: AT3G29760.3 Haloacid dehalogenase-like hydrolase (HAD) superfamily protein; Swiss-Prot: sp|O94336|YHM3_SCHPO Uncharacterized FCP1 homology domain-containing protein C1271.03c; TrEMBL-Plants: tr|K7MW97|K7MW97_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0267000 | 10 | ||
| – | Haloacid dehalogenase-like hydrolase (HAD) superfamily protein; TAIR: AT3G29760.3 Haloacid dehalogenase-like hydrolase (HAD) superfamily protein; Swiss-Prot: sp|O94336|YHM3_SCHPO Uncharacterized FCP1 homology domain-containing protein C1271.03c; TrEMBL-Plants: tr|K7MW97|K7MW97_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0267000 | 10 | ||
| – | Serine/threonine-protein phosphatase 7 long form-like protein; TAIR: AT2G04865.1 Aminotransferase-like, plant mobile domain family protein; Swiss-Prot: sp|F4IFD0|MAIL2_ARATH Protein MAIN-LIKE 2; TrEMBL-Plants: tr|A2Q553|A2Q553_MEDTR Putative uncharacterized protein; Found in the gene: LotjaGi2g1v0319200_LC | 11 | ||
| – | CTD small phosphatase-like protein; TAIR: AT5G46410.1 SCP1-like small phosphatase 4; Swiss-Prot: sp|Q54GB2|CTSL2_DICDI CTD small phosphatase-like protein 2; TrEMBL-Plants: tr|A0A072UU09|A0A072UU09_MEDTR NLI interacting factor-like phosphatase; Found in the gene: LotjaGi3g1v0101500 | 14 | ||
| – | CTD small phosphatase-like protein; TAIR: AT5G46410.1 SCP1-like small phosphatase 4; Swiss-Prot: sp|Q54GB2|CTSL2_DICDI CTD small phosphatase-like protein 2; TrEMBL-Plants: tr|A0A072UU09|A0A072UU09_MEDTR NLI interacting factor-like phosphatase; Found in the gene: LotjaGi3g1v0101500 | 14 | ||
| – | RNA polymerase II C-terminal domain phosphatase-like 1; TAIR: AT4G21670.1 C-terminal domain phosphatase-like 1; Swiss-Prot: sp|Q5YDB6|CPL1_ARATH RNA polymerase II C-terminal domain phosphatase-like 1; TrEMBL-Plants: tr|A0A0S3QZI5|A0A0S3QZI5_PHAAN Uncharacterized protein; Found in the gene: LotjaGi4g1v0054200 | 18 | ||
| – | RNA polymerase II C-terminal domain phosphatase-like protein; TAIR: AT5G58003.3 C-terminal domain phosphatase-like 4; Swiss-Prot: sp|Q00IB6|CPL4_ARATH RNA polymerase II C-terminal domain phosphatase-like 4; TrEMBL-Plants: tr|A0A151SFP9|A0A151SFP9_CAJCA Uncharacterized protein; Found in the gene: LotjaGi4g1v0286500 | 14 | ||
| – | RNA polymerase II C-terminal domain phosphatase-like protein; TAIR: AT5G58003.1 C-terminal domain phosphatase-like 4; Swiss-Prot: sp|Q00IB6|CPL4_ARATH RNA polymerase II C-terminal domain phosphatase-like 4; TrEMBL-Plants: tr|V7BX02|V7BX02_PHAVU Uncharacterized protein; Found in the gene: LotjaGi4g1v0287100 | 23 | ||
| – | RNA polymerase II C-terminal domain phosphatase-like protein; TAIR: AT5G58003.1 C-terminal domain phosphatase-like 4; Swiss-Prot: sp|Q00IB6|CPL4_ARATH RNA polymerase II C-terminal domain phosphatase-like 4; TrEMBL-Plants: tr|A0A0L9TRV4|A0A0L9TRV4_PHAAN Uncharacterized protein; Found in the gene: LotjaGi4g1v0287100 | 22 | ||
| – | Ubiquitin-like domain-containing CTD phosphatase; TAIR: AT4G06599.1 ubiquitin family protein; Swiss-Prot: sp|Q8W3M6|UBCP_ARATH Ubiquitin-like domain-containing CTD phosphatase; TrEMBL-Plants: tr|I3SL87|I3SL87_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0387500 | 21 | ||
| – | CTD small phosphatase-like protein; TAIR: AT3G55960.1 Haloacid dehalogenase-like hydrolase (HAD) superfamily protein; Swiss-Prot: sp|Q9GZU7|CTDS1_HUMAN Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1; TrEMBL-Plants: tr|I3S2I8|I3S2I8_LOTJA Uncharacterized protein; Found in the gene: LotjaGi6g1v0075800 | 17 | ||
| – | CTD small phosphatase-like protein; TAIR: AT5G11860.1 SCP1-like small phosphatase 5; Swiss-Prot: sp|Q54GB2|CTSL2_DICDI CTD small phosphatase-like protein 2; TrEMBL-Plants: tr|A0A0L9T4D7|A0A0L9T4D7_PHAAN Uncharacterized protein; Found in the gene: LotjaGi6g1v0101600 | 15 | ||
| – | CTD small phosphatase-like protein; TAIR: AT5G46410.1 SCP1-like small phosphatase 4; Swiss-Prot: sp|Q54GB2|CTSL2_DICDI CTD small phosphatase-like protein 2; TrEMBL-Plants: tr|A0A151S1P8|A0A151S1P8_CAJCA CTD small phosphatase-like protein 2; Found in the gene: LotjaGi6g1v0211000 | 14 | ||
| – | CTD small phosphatase-like protein; TAIR: AT5G46410.1 SCP1-like small phosphatase 4; Swiss-Prot: sp|Q54GB2|CTSL2_DICDI CTD small phosphatase-like protein 2; TrEMBL-Plants: tr|A0A151S1P8|A0A151S1P8_CAJCA CTD small phosphatase-like protein 2; Found in the gene: LotjaGi6g1v0211000 | 14 | ||
| – | CTD small phosphatase-like protein; TAIR: AT5G45700.1 Haloacid dehalogenase-like hydrolase (HAD) superfamily protein; Swiss-Prot: sp|Q9PTJ6|CTDSL_CHICK CTD small phosphatase-like protein; TrEMBL-Plants: tr|K7M175|K7M175_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0317800 | 14 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 1.67 |