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IPR012110

Source: InterPro

Description

IPR012110 is a Pyruvate decarboxylase/indolepyruvate decarboxylase-like.

<p>This entry represents part of a family of closely related, thiamine pyrophosphate-dependent enzymes includes indolepyruvate decarboxylase (IPDC, [ec:4.1.1.74])[[cite:PUB00015910], [cite:PUB00102228]], pyruvate decarboxylase (PDC, [ec:4.1.1.1]) [[cite:PUB00102234]], branched-chain alpha-ketoacid decarboxylase, etc [[cite:PUB00042068]]. PDC catalyses the conversion of pyruvate to acetaldehyde and CO2 in alcoholic fermentation. IPDC plays a role in the indole-3-pyruvic acid (IPA) pathway in plants and various plant-associated bacteria, it catalyses the decarboxylation of IPA to IAA. Also belonging to this entry is Mycobacterium tuberculosis alpha-keto acid decarboxylase (MtKDC) which participates in amino acid degradation via the Ehrlich pathway [[cite:PUB00102231]], and Lactococcus lactis branched-chain keto acid decarboxylase (KdcA) an enzyme identified as being involved in cheese ripening, which exhibits a very broad substrate range in the decarboxylation and carboligation reactions [[cite:PUB00049666]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0016831
Molecular function Carboxy-lyase activity Catalysis of the nonhydrolytic addition or removal of a carboxyl group to or from a compound.
Subterm of

Associated Lotus transcripts 10

Transcript Name Description Predicted domains Domain count
Lj0g3v0332289.1
– Thiamine pyrophosphate dependent pyruvate decarboxylase family protein [Theobroma cacao] gi|508715239|gb|EOY07136.1|
Domains
19
Lj1g3v2372300.1
– Pyruvate decarboxylase 1 [Lotus corniculatus] gi|29373077|gb|AAO72533.1|
Domains
18
Lj6g3v1995950.1
– Pyruvate decarboxylase isozyme 1 [Lotus japonicus] gi|51587336|emb|CAG30578.1|
Domains
18
Lj6g3v1995960.1
–
Domains
18
LotjaGi1g1v0443800.1
– Pyruvate decarboxylase; TAIR: AT4G33070.1 Thiamine pyrophosphate dependent pyruvate decarboxylase family protein; Swiss-Prot: sp|O82647|PDC1_ARATH Pyruvate decarboxylase 1; TrEMBL-Plants: tr|Q84V95|Q84V95_LOTCO Pyruvate decarboxylase 1; Found in the gene: LotjaGi1g1v0443800
Domains
18
LotjaGi1g1v0443800.3
– Pyruvate decarboxylase; TAIR: AT4G33070.1 Thiamine pyrophosphate dependent pyruvate decarboxylase family protein; Swiss-Prot: sp|O82647|PDC1_ARATH Pyruvate decarboxylase 1; TrEMBL-Plants: tr|Q84V95|Q84V95_LOTCO Pyruvate decarboxylase 1; Found in the gene: LotjaGi1g1v0443800
Domains
18
LotjaGi3g1v0195000.1
– Pyruvate decarboxylase; TAIR: AT5G54960.1 pyruvate decarboxylase-2; Swiss-Prot: sp|Q9FFT4|PDC2_ARATH Pyruvate decarboxylase 2; TrEMBL-Plants: tr|A0A061EQM3|A0A061EQM3_THECC Thiamine pyrophosphate dependent pyruvate decarboxylase family protein; Found in the gene: LotjaGi3g1v0195000
Domains
19
LotjaGi3g1v0195000.2
– Pyruvate decarboxylase; TAIR: AT5G54960.1 pyruvate decarboxylase-2; Swiss-Prot: sp|Q9FFT4|PDC2_ARATH Pyruvate decarboxylase 2; TrEMBL-Plants: tr|A0A061EQM3|A0A061EQM3_THECC Thiamine pyrophosphate dependent pyruvate decarboxylase family protein; Found in the gene: LotjaGi3g1v0195000
Domains
19
LotjaGi3g1v0195000.3
– Pyruvate decarboxylase; TAIR: AT5G54960.1 pyruvate decarboxylase-2; Swiss-Prot: sp|Q9FFT4|PDC2_ARATH Pyruvate decarboxylase 2; TrEMBL-Plants: tr|A0A061EQM3|A0A061EQM3_THECC Thiamine pyrophosphate dependent pyruvate decarboxylase family protein; Found in the gene: LotjaGi3g1v0195000
Domains
19
LotjaGi6g1v0324800.1
– Pyruvate decarboxylase; TAIR: AT5G54960.1 pyruvate decarboxylase-2; Swiss-Prot: sp|P51850|PDC1_PEA Pyruvate decarboxylase 1; TrEMBL-Plants: tr|Q684K0|Q684K0_LOTJA Pyruvate decarboxylase isozyme 1; Found in the gene: LotjaGi6g1v0324800
Domains
18

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
cd07038 CDD 1 10.00