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IPR014012 is a Helicase/SANT-associated domain.
<p>The helicase/SANT-associated (HSA) domain is found in eukaryotic proteins, including Helicase SRCAP/p400/DOM [[cite:PUB00033613]], Probable global transcription activator SNF2L2/brahma-homologue and Chromatin modification-related protein EAF1 [[cite:PUB00046117]]. While each family has the core sequences that define the HSA domain, they each also have additional sequences that distinguish these families from one another. For example, the sequence HWDY(L/C)EEEM(Q/V) is found in the SRCAP/p400/DOM family, whereas the sequence HQE(Y/F)LNSILQ is found in the SNF2 /brahma family [[cite:PUB00033613]]. HSA was initially predicted to be a DNA-binding domain [[cite:PUB00011448]], but it was later reported to be responsible for the binding to nuclear actin-related proteins (ARPs) and actin [[cite:PUB00101183]]. In addition to the SANT and helicase domains, the HSA domain is also found in association with the bromo domain [[cite:PUB00011448]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | Helicase/SANT-associated, DNA binding protein [Arabidopsis thaliana] gi|42565171|ref|NP_189132.2| | 5 | ||
| – | PREDICTED: chromatin structure-remodeling complex protein SYD-like isoform X2 [Cicer arietinum] gi|502151178|ref|XP_004508316.1| | 8 | ||
| – | PREDICTED: helicase SRCAP-like [Cicer arietinum] gi|502122805|ref|XP_004497900.1| | 5 | ||
| – | PREDICTED: helicase SRCAP-like [Cicer arietinum] gi|502122805|ref|XP_004497900.1| | 7 | ||
| – | Helicase/SANT-associated, DNA binding protein [Arabidopsis thaliana] gi|42565171|ref|NP_189132.2| | 5 | ||
| – | PREDICTED: chromatin structure-remodeling complex protein SYD-like isoform X2 [Cicer arietinum] gi|502151178|ref|XP_004508316.1| | 8 | ||
| – | PREDICTED: helicase SRCAP-like [Cicer arietinum] gi|502122805|ref|XP_004497900.1| | 26 | ||
| – | Helicase/SANT-associated, DNA-binding protein, putative; TAIR: AT3G24880.1 Helicase/SANT-associated, DNA binding protein; Swiss-Prot: sp|F4J7T3|EAF1A_ARATH Chromatin modification-related protein EAF1 A; TrEMBL-Plants: tr|A0A0R0J4B4|A0A0R0J4B4_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0587600 | 14 | ||
| – | Helicase/SANT-associated, DNA-binding protein, putative; TAIR: AT3G24880.2 Helicase/SANT-associated, DNA binding protein; Swiss-Prot: sp|F4J7T3|EAF1A_ARATH Chromatin modification-related protein EAF1 A; TrEMBL-Plants: tr|A0A072UA52|A0A072UA52_MEDTR Helicase/SANT-associated, DNA-binding protein, putative; Found in the gene: LotjaGi1g1v0587600 | 14 | ||
| – | Helicase/SANT-associated, DNA-binding protein, putative; TAIR: AT3G24880.2 Helicase/SANT-associated, DNA binding protein; Swiss-Prot: sp|F4J7T3|EAF1A_ARATH Chromatin modification-related protein EAF1 A; TrEMBL-Plants: tr|A0A0R0FX49|A0A0R0FX49_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0083100 | 13 | ||
| – | Helicase/SANT-associated, DNA-binding protein, putative; TAIR: AT3G24880.2 Helicase/SANT-associated, DNA binding protein; Swiss-Prot: sp|F4J7T3|EAF1A_ARATH Chromatin modification-related protein EAF1 A; TrEMBL-Plants: tr|A0A0R0FX49|A0A0R0FX49_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0083100 | 13 | ||
| – | Chromatin remodeling 1; TAIR: AT2G28290.1 P-loop containing nucleoside triphosphate hydrolases superfamily protein; Swiss-Prot: sp|F4IHS2|SYD_ARATH Chromatin structure-remodeling complex protein SYD; TrEMBL-Plants: tr|V7CA49|V7CA49_PHAVU Uncharacterized protein; Found in the gene: LotjaGi4g1v0346800 | 27 | ||
| – | Chromatin structure-remodeling complex subunit snf21; TAIR: AT2G28290.1 P-loop containing nucleoside triphosphate hydrolases superfamily protein; Swiss-Prot: sp|F4IHS2|SYD_ARATH Chromatin structure-remodeling complex protein SYD; TrEMBL-Plants: tr|M5XIB1|M5XIB1_PRUPE Uncharacterized protein; Found in the gene: LotjaGi6g1v0305000 | 5 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| PTHR10799:SF973 | PANTHER | 1 | 7.69 |