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IPR020813

Source: InterPro

Description

IPR020813 is a Fibrillarin, conserved site.

<p>Fibrillarin is a component of a nucleolar small nuclear ribonucleoprotein (SnRNP), functioning<i>in vivo</i> in ribosomal RNA processing [[cite:PUB00003067], [cite:PUB00004418]]. It is associated with U3, U8 and U13 small nuclear RNAs in mammals [[cite:PUB00003067]] and is similar to the yeast NOP1 protein [[cite:PUB00001181]]. Fibrillarin has a well conserved sequence of around 320 amino acids, and contains 3 domains, an N-terminal Gly/Arg-rich region; a central domain resembling other RNA-binding proteins and containing an RNP-2-like consensus sequence; and a C-terminal α-helical domain. An evolutionarily related pre-rRNA processing protein, which lacks the Gly/Arg-rich domain, has been found in various archaebacteria.</p> <p>The signature pattern for this entry encompasses the RNP-2 like octapeptide sequence.</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0003723
Molecular function RNA binding Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
Subterm of
GO:0006364
Biological process RRNA processing Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules.
Subterm of
Part of
GO:0008168
Molecular function Methyltransferase activity Catalysis of the transfer of a methyl group to an acceptor molecule.
Subterm of

Associated Lotus transcripts 6

Transcript Name Description Predicted domains Domain count
Lj0g3v0107099.1
– PREDICTED: rRNA 2'-O-methyltransferase fibrillarin 2-like [Glycine max] gi|356518852|ref|XP_003528091.1|
Domains
13
Lj0g3v0201389.1
– Fibrillarin [Medicago truncatula] gi|357444829|ref|XP_003592692.1|
Domains
13
LotjaGi1g1v0018400.1
– RRNA 2'-O-methyltransferase fibrillarin 2; TAIR: AT4G25630.1 fibrillarin 2; Swiss-Prot: sp|Q94AH9|MD36A_ARATH Mediator of RNA polymerase II transcription subunit 36a; TrEMBL-Plants: tr|I3SKZ0|I3SKZ0_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0018400
Domains
15
LotjaGi1g1v0018400.2
– RRNA 2'-O-methyltransferase fibrillarin 2; TAIR: AT4G25630.1 fibrillarin 2; Swiss-Prot: sp|Q94AH9|MD36A_ARATH Mediator of RNA polymerase II transcription subunit 36a; TrEMBL-Plants: tr|I3SKZ0|I3SKZ0_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0018400
Domains
14
LotjaGi1g1v0018400.3
– RRNA 2'-O-methyltransferase fibrillarin 2; TAIR: AT4G25630.1 fibrillarin 2; Swiss-Prot: sp|Q94AH9|MD36A_ARATH Mediator of RNA polymerase II transcription subunit 36a; TrEMBL-Plants: tr|I3SKZ0|I3SKZ0_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0018400
Domains
14
LotjaGi2g1v0122000.1
– RRNA 2'-O-methyltransferase fibrillarin 2; TAIR: AT4G25630.1 fibrillarin 2; Swiss-Prot: sp|Q94AH9|MD36A_ARATH Mediator of RNA polymerase II transcription subunit 36a; TrEMBL-Plants: tr|I3SKZ0|I3SKZ0_LOTJA Uncharacterized protein; Found in the gene: LotjaGi2g1v0122000
Domains
15

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 16.67