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IPR033939

Source: InterPro

Description

IPR033939 is a Branched-chain aminotransferase.

<p>Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids leucine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and alpha-ketoisovalerate. The enzyme requires pyridoxal 5'-phosphate (PLP) as a cofactor to catalyze the reaction. It has been found that mammals have two forms of the enzyme - mitochondrial and cytosolic forms while bacteria contain only one form of the enzyme [[cite:PUB00081811]]. The mitochondrial form plays a significant role in skeletal muscle glutamine and alanine synthesis and in interorgan nitrogen metabolism [[cite:PUB00081812]]. Members of this entry are widely distributed in all three forms of life.</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0004084
Molecular function Branched-chain-amino-acid transaminase activity Catalysis of the reaction: a branched-chain amino acid + 2-oxoglutarate = L-glutamate + a 2-oxocarboxylate derived from the branched-chain amino acid.
Subterm of
GO:0009081
Biological process Branched-chain amino acid metabolic process The chemical reactions and pathways involving amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine.
Subterm of

Associated Lotus transcripts 18

Transcript Name Description Predicted domains Domain count
Lj0g3v0097809.1
– Branched amino acid transaminase [Vigna unguiculata] gi|457866473|dbj|BAM93581.1|
Domains
14
Lj0g3v0334729.1
– PREDICTED: branched-chain-amino-acid aminotransferase 2, chloroplastic-like [Glycine max] gi|356510642|ref|XP_003524046.1|
Domains
15
Lj0g3v0334729.2
– Branched amino acid transaminase [Vigna unguiculata] gi|457866473|dbj|BAM93581.1|
Domains
14
Lj2g3v1983990.1
– Branched-chain-amino-acid aminotransferase [Medicago truncatula] gi|357482487|ref|XP_003611530.1|
Domains
14
Lj4g3v0412790.1
– PREDICTED: branched-chain-amino-acid aminotransferase 2, chloroplastic-like isoform X1 [Cicer arietinum] gi|502142305|ref|XP_004504892.1|
Domains
14
Lj4g3v0412790.2
– PREDICTED: branched-chain-amino-acid aminotransferase 2, chloroplastic-like isoform X1 [Cicer arietinum] gi|502142305|ref|XP_004504892.1|
Domains
14
LotjaGi1g1v0364300.1
– Branched-chain-amino-acid aminotransferase; TAIR: AT1G10070.1 branched-chain amino acid transaminase 2; Swiss-Prot: sp|Q9M439|BCAT2_ARATH Branched-chain-amino-acid aminotransferase 2, chloroplastic; TrEMBL-Plants: tr|A0A072V3G0|A0A072V3G0_MEDTR Branched-chain-amino-acid aminotransferase; Found in the gene: LotjaGi1g1v0364300
Domains
17
LotjaGi1g1v0364300.2
– Branched-chain-amino-acid aminotransferase; TAIR: AT1G10070.1 branched-chain amino acid transaminase 2; Swiss-Prot: sp|Q9M439|BCAT2_ARATH Branched-chain-amino-acid aminotransferase 2, chloroplastic; TrEMBL-Plants: tr|A0A072V3G0|A0A072V3G0_MEDTR Branched-chain-amino-acid aminotransferase; Found in the gene: LotjaGi1g1v0364300
Domains
18
LotjaGi1g1v0364300.3
– Branched-chain-amino-acid aminotransferase; TAIR: AT1G10070.1 branched-chain amino acid transaminase 2; Swiss-Prot: sp|Q9M439|BCAT2_ARATH Branched-chain-amino-acid aminotransferase 2, chloroplastic; TrEMBL-Plants: tr|A0A072V1K9|A0A072V1K9_MEDTR Branched-chain-amino-acid aminotransferase; Found in the gene: LotjaGi1g1v0364300
Domains
17
LotjaGi1g1v0364300.4
– Branched-chain-amino-acid aminotransferase; TAIR: AT1G10070.1 branched-chain amino acid transaminase 2; Swiss-Prot: sp|Q9M439|BCAT2_ARATH Branched-chain-amino-acid aminotransferase 2, chloroplastic; TrEMBL-Plants: tr|A0A072V1K9|A0A072V1K9_MEDTR Branched-chain-amino-acid aminotransferase; Found in the gene: LotjaGi1g1v0364300
Domains
17
LotjaGi1g1v0364300.5
– Branched-chain-amino-acid aminotransferase; TAIR: AT1G10070.1 branched-chain amino acid transaminase 2; Swiss-Prot: sp|Q9M439|BCAT2_ARATH Branched-chain-amino-acid aminotransferase 2, chloroplastic; TrEMBL-Plants: tr|A0A072V3G0|A0A072V3G0_MEDTR Branched-chain-amino-acid aminotransferase; Found in the gene: LotjaGi1g1v0364300
Domains
17
LotjaGi1g1v0364300.6
– Branched-chain-amino-acid aminotransferase; TAIR: AT1G10070.1 branched-chain amino acid transaminase 2; Swiss-Prot: sp|Q9M439|BCAT2_ARATH Branched-chain-amino-acid aminotransferase 2, chloroplastic; TrEMBL-Plants: tr|A0A072V3G0|A0A072V3G0_MEDTR Branched-chain-amino-acid aminotransferase; Found in the gene: LotjaGi1g1v0364300
Domains
18
LotjaGi1g1v0364300.7
– Branched-chain-amino-acid aminotransferase; TAIR: AT1G10070.1 branched-chain amino acid transaminase 2; Swiss-Prot: sp|Q9M439|BCAT2_ARATH Branched-chain-amino-acid aminotransferase 2, chloroplastic; TrEMBL-Plants: tr|A0A072V1K9|A0A072V1K9_MEDTR Branched-chain-amino-acid aminotransferase; Found in the gene: LotjaGi1g1v0364300
Domains
17
LotjaGi1g1v0364500.1
– Branched-chain-amino-acid aminotransferase; TAIR: AT1G10070.1 branched-chain amino acid transaminase 2; Swiss-Prot: sp|Q9M439|BCAT2_ARATH Branched-chain-amino-acid aminotransferase 2, chloroplastic; TrEMBL-Plants: tr|A0A072V3G0|A0A072V3G0_MEDTR Branched-chain-amino-acid aminotransferase; Found in the gene: LotjaGi1g1v0364500
Domains
17
LotjaGi1g1v0364500.2
– Branched-chain-amino-acid aminotransferase; TAIR: AT1G10070.1 branched-chain amino acid transaminase 2; Swiss-Prot: sp|Q9M439|BCAT2_ARATH Branched-chain-amino-acid aminotransferase 2, chloroplastic; TrEMBL-Plants: tr|A0A072V3G0|A0A072V3G0_MEDTR Branched-chain-amino-acid aminotransferase; Found in the gene: LotjaGi1g1v0364500
Domains
16
LotjaGi2g1v0412400.1
– Branched-chain-amino-acid aminotransferase; TAIR: AT3G49680.1 branched-chain aminotransferase 3; Swiss-Prot: sp|Q9M401|BCAT3_ARATH Branched-chain-amino-acid aminotransferase 3, chloroplastic; TrEMBL-Plants: tr|I3S9H6|I3S9H6_LOTJA Branched-chain-amino-acid aminotransferase; Found in the gene: LotjaGi2g1v0412400
Domains
17
LotjaGi4g1v0044400.1
– Branched-chain-amino-acid aminotransferase; TAIR: AT1G50090.1 D-aminoacid aminotransferase-like PLP-dependent enzymes superfamily protein; Swiss-Prot: sp|Q9LPM8|BCAT7_ARATH Putative branched-chain-amino-acid aminotransferase 7; TrEMBL-Plants: tr|A0A151SI87|A0A151SI87_CAJCA Branched-chain-amino-acid aminotransferase; Found in the gene: LotjaGi4g1v0044400
Domains
17
LotjaGi4g1v0044400.2
– Branched-chain-amino-acid aminotransferase; TAIR: AT1G50110.1 D-aminoacid aminotransferase-like PLP-dependent enzymes superfamily protein; Swiss-Prot: sp|Q9LPM9|BCAT6_ARATH Branched-chain-amino-acid aminotransferase 6; TrEMBL-Plants: tr|A0A151SI87|A0A151SI87_CAJCA Branched-chain-amino-acid aminotransferase; Found in the gene: LotjaGi4g1v0044400
Domains
17

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
cd01557 CDD 1 5.56