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IPR036353 is a XPC-binding domain superfamily.
<p>This domain adopts a structure consisting of four α-helices, arranged in an array. It binds specifically and directly to the xeroderma pigmentosum group C protein (XPC) to initiate nucleotide excision repair [[cite:PUB00035489]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | Damaged DNA binding | Interacting selectively and non-covalently with damaged DNA. | ||
| Biological process | Nucleotide-excision repair | A DNA repair process in which a small region of the strand surrounding the damage is removed from the DNA helix as an oligonucleotide. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase. Nucleotide excision repair recognizes a wide range of substrates, including damage caused by UV irradiation (pyrimidine dimers and 6-4 photoproducts) and chemicals (intrastrand cross-links and bulky adducts). | ||
| Biological process | Proteasome-mediated ubiquitin-dependent protein catabolic process | The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | RAD23 UV excision repair family protein; TAIR: AT5G38470.1 Rad23 UV excision repair protein family; Swiss-Prot: sp|Q84L30|RD23D_ARATH Ubiquitin receptor RAD23d; TrEMBL-Plants: tr|I3SBD5|I3SBD5_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0550600 | 28 | ||
| – | RAD23 UV excision repair family protein; TAIR: AT3G02540.3 Rad23 UV excision repair protein family; Swiss-Prot: sp|Q84L31|RD23C_ARATH Ubiquitin receptor RAD23c; TrEMBL-Plants: tr|A0A151RI27|A0A151RI27_CAJCA Putative DNA repair protein RAD23-3; Found in the gene: LotjaGi2g1v0277900 | 30 | ||
| – | Ubiquitin family protein; TAIR: AT1G79650.2 Rad23 UV excision repair protein family; Swiss-Prot: sp|Q84L33|RD23B_ARATH Ubiquitin receptor RAD23b; TrEMBL-Plants: tr|A0A0S3SF25|A0A0S3SF25_PHAAN Uncharacterized protein; Found in the gene: LotjaGi3g1v0002300 | 28 | ||
| – | RAD23 UV excision repair family protein; TAIR: AT3G02540.1 Rad23 UV excision repair protein family; Swiss-Prot: sp|Q84L31|RD23C_ARATH Ubiquitin receptor RAD23c; TrEMBL-Plants: tr|A0A0L9U0N9|A0A0L9U0N9_PHAAN Uncharacterized protein; Found in the gene: LotjaGi5g1v0340800 | 16 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| SSF46934 | SUPERFAMILY | 1 | 25.00 |