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IPR039385 is a NGN domain, eukaryotic.
<p>The N-Utilization Substance G (NusG) protein and its eukaryotic homologue, Spt5, are involved in transcription elongation and termination. NusG contains an NGN domain at its N terminus and Kyrpides Ouzounis and Woese (KOW) repeats at its C terminus. Spt5 forms an Spt4-Spt5 complex that is an essential RNA polymerase II elongation factor. NusG was originally discovered as an N-dependent antitermination enhancing activity in Escherichia coli, and has a variety of functions such as its involvement in RNA polymerase elongation and Rho-termination in bacteria. Orthologues of the NusG gene exist in all bacteria, but their functions and requirements are different. Spt5-like is homologous to the Spt5 proteins present in all eukaryotes, which is unique as it encodes a protein with an additional long carboxy-terminal extension that contains WG/GW motifs. Spt5-like, or KTF1 (KOW domain-containing Transcription Factor 1), is a RNA-directed DNA methylation (RdDM) pathway effector in plants [[cite:PUB00089565], [cite:PUB00009700]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | Transcription elongation factor SPT5; TAIR: AT4G08350.1 global transcription factor group A2; Swiss-Prot: sp|Q9STN3|SPT51_ARATH Putative transcription elongation factor SPT5 homolog 1; TrEMBL-Plants: tr|I1JYX6|I1JYX6_SOYBN Transcription elongation factor SPT5; Found in the gene: LotjaGi1g1v0273000 | 37 | ||
| – | Transcription elongation factor Spt5-like protein, putative; TAIR: AT5G04290.2 kow domain-containing transcription factor 1; Swiss-Prot: sp|F4JW79|RDM3_ARATH Protein RNA-directed DNA methylation 3; TrEMBL-Plants: tr|A0A072VS63|A0A072VS63_MEDTR Transcription elongation factor Spt5-like protein, putative; Found in the gene: LotjaGi5g1v0342300_LC | 18 | ||
| – | Transcription elongation factor Spt5-like protein, putative; TAIR: AT5G04290.2 kow domain-containing transcription factor 1; Swiss-Prot: sp|F4JW79|RDM3_ARATH Protein RNA-directed DNA methylation 3; TrEMBL-Plants: tr|A0A072VS63|A0A072VS63_MEDTR Transcription elongation factor Spt5-like protein, putative; Found in the gene: LotjaGi5g1v0342300_LC | 18 | ||
| – | Transcription elongation factor Spt5-like protein, putative; TAIR: AT5G04290.2 kow domain-containing transcription factor 1; Swiss-Prot: sp|F4JW79|RDM3_ARATH Protein RNA-directed DNA methylation 3; TrEMBL-Plants: tr|A0A072VS63|A0A072VS63_MEDTR Transcription elongation factor Spt5-like protein, putative; Found in the gene: LotjaGi5g1v0342300_LC | 18 | ||
| – | Transcription elongation factor Spt5-like protein, putative; TAIR: AT5G04290.2 kow domain-containing transcription factor 1; Swiss-Prot: sp|F4JW79|RDM3_ARATH Protein RNA-directed DNA methylation 3; TrEMBL-Plants: tr|A0A072VS63|A0A072VS63_MEDTR Transcription elongation factor Spt5-like protein, putative; Found in the gene: LotjaGi5g1v0342300_LC | 18 | ||
| – | Transcription elongation factor Spt5-like protein, putative; TAIR: AT5G04290.2 kow domain-containing transcription factor 1; Swiss-Prot: sp|F4JW79|RDM3_ARATH Protein RNA-directed DNA methylation 3; TrEMBL-Plants: tr|A0A072VS63|A0A072VS63_MEDTR Transcription elongation factor Spt5-like protein, putative; Found in the gene: LotjaGi5g1v0342300_LC | 18 | ||
| – | Transcription elongation factor Spt5-like protein, putative; TAIR: AT5G04290.2 kow domain-containing transcription factor 1; Swiss-Prot: sp|F4JW79|RDM3_ARATH Protein RNA-directed DNA methylation 3; TrEMBL-Plants: tr|A0A072VS63|A0A072VS63_MEDTR Transcription elongation factor Spt5-like protein, putative; Found in the gene: LotjaGi5g1v0342300_LC | 18 | ||
| – | Transcription elongation factor Spt5-like protein, putative; TAIR: AT5G04290.2 kow domain-containing transcription factor 1; Swiss-Prot: sp|F4JW79|RDM3_ARATH Protein RNA-directed DNA methylation 3; TrEMBL-Plants: tr|A0A072VS63|A0A072VS63_MEDTR Transcription elongation factor Spt5-like protein, putative; Found in the gene: LotjaGi5g1v0342300_LC | 18 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 12.50 |