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IPR039659

Description

IPR039659 is a Transcription elongation factor SPT5.

<p>Transcription elongation factor Spt5 is found in both eukaryotes and archaea. Spt5 forms a heterodimer with Spt4 and collaborates with other transcription factors to pause or promote RNA polymerase II transcription elongation [[cite:PUB00090193]]. It has been demonstrated that Spt4, Spt5, and Spt6 play roles in transcription elongation in both yeast and humans, including a role in activation by Tat. It is known that Spt4, Spt5, and Spt6 are general transcription-elongation factors, controlling transcription both positively and negatively in important regulatory and developmental roles [[cite:PUB00012261]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
Biological process Regulation of transcription by RNA polymerase II Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.
Biological process Regulation of DNA-templated transcription, elongation Any process that modulates the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides catalyzed by a DNA-dependent RNA polymerase.

Associated Lotus transcripts 8

Transcript Name Description Predicted domains Domain count
Transcription elongation factor SPT5; TAIR: AT4G08350.1 global transcription factor group A2; Swiss-Prot: sp|Q9STN3|SPT51_ARATH Putative transcription elongation factor SPT5 homolog 1; TrEMBL-Plants: tr|I1JYX6|I1JYX6_SOYBN Transcription elongation factor SPT5; Found in the gene: LotjaGi1g1v0273000 37
Transcription elongation factor Spt5-like protein, putative; TAIR: AT5G04290.2 kow domain-containing transcription factor 1; Swiss-Prot: sp|F4JW79|RDM3_ARATH Protein RNA-directed DNA methylation 3; TrEMBL-Plants: tr|A0A072VS63|A0A072VS63_MEDTR Transcription elongation factor Spt5-like protein, putative; Found in the gene: LotjaGi5g1v0342300_LC 18
Transcription elongation factor Spt5-like protein, putative; TAIR: AT5G04290.2 kow domain-containing transcription factor 1; Swiss-Prot: sp|F4JW79|RDM3_ARATH Protein RNA-directed DNA methylation 3; TrEMBL-Plants: tr|A0A072VS63|A0A072VS63_MEDTR Transcription elongation factor Spt5-like protein, putative; Found in the gene: LotjaGi5g1v0342300_LC 18
Transcription elongation factor Spt5-like protein, putative; TAIR: AT5G04290.2 kow domain-containing transcription factor 1; Swiss-Prot: sp|F4JW79|RDM3_ARATH Protein RNA-directed DNA methylation 3; TrEMBL-Plants: tr|A0A072VS63|A0A072VS63_MEDTR Transcription elongation factor Spt5-like protein, putative; Found in the gene: LotjaGi5g1v0342300_LC 18
Transcription elongation factor Spt5-like protein, putative; TAIR: AT5G04290.2 kow domain-containing transcription factor 1; Swiss-Prot: sp|F4JW79|RDM3_ARATH Protein RNA-directed DNA methylation 3; TrEMBL-Plants: tr|A0A072VS63|A0A072VS63_MEDTR Transcription elongation factor Spt5-like protein, putative; Found in the gene: LotjaGi5g1v0342300_LC 18
Transcription elongation factor Spt5-like protein, putative; TAIR: AT5G04290.2 kow domain-containing transcription factor 1; Swiss-Prot: sp|F4JW79|RDM3_ARATH Protein RNA-directed DNA methylation 3; TrEMBL-Plants: tr|A0A072VS63|A0A072VS63_MEDTR Transcription elongation factor Spt5-like protein, putative; Found in the gene: LotjaGi5g1v0342300_LC 18
Transcription elongation factor Spt5-like protein, putative; TAIR: AT5G04290.2 kow domain-containing transcription factor 1; Swiss-Prot: sp|F4JW79|RDM3_ARATH Protein RNA-directed DNA methylation 3; TrEMBL-Plants: tr|A0A072VS63|A0A072VS63_MEDTR Transcription elongation factor Spt5-like protein, putative; Found in the gene: LotjaGi5g1v0342300_LC 18
Transcription elongation factor Spt5-like protein, putative; TAIR: AT5G04290.2 kow domain-containing transcription factor 1; Swiss-Prot: sp|F4JW79|RDM3_ARATH Protein RNA-directed DNA methylation 3; TrEMBL-Plants: tr|A0A072VS63|A0A072VS63_MEDTR Transcription elongation factor Spt5-like protein, putative; Found in the gene: LotjaGi5g1v0342300_LC 18

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 12.50