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IPR039762

Source: InterPro

Description

IPR039762 is a Nonsense-mediated mRNA decay protein Nmd2/UPF2.

<p>This entry includes Nmd2 from yeasts and UPF2 from animals. They are involved in the nonsense-mediated mRNA decay (NMD) pathway [[cite:PUB00090013], [cite:PUB00084768]]. In the human UPF complex (composed of UPF1/2/3), UPF2 and UPF3b cooperatively stimulate both ATPase and RNA helicase activities of UPF1 [[cite:PUB00090071]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0000184
Biological process Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay The nonsense-mediated decay pathway for nuclear-transcribed mRNAs degrades mRNAs in which an amino-acid codon has changed to a nonsense codon; this prevents the translation of such mRNAs into truncated, and potentially harmful, proteins.
Subterm of

Associated Lotus transcripts 8

Transcript Name Description Predicted domains Domain count
LotjaGi6g1v0212500.1
– Regulator of nonsense transcripts 2; TAIR: AT2G39260.1 regulator of nonsense transcripts UPF2; Swiss-Prot: sp|F4IUX6|RENT2_ARATH Regulator of nonsense transcripts UPF2; TrEMBL-Plants: tr|I1MHT6|I1MHT6_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0212500
Domains
15
LotjaGi6g1v0212500.2
– Regulator of nonsense transcripts 2; TAIR: AT2G39260.1 regulator of nonsense transcripts UPF2; Swiss-Prot: sp|F4IUX6|RENT2_ARATH Regulator of nonsense transcripts UPF2; TrEMBL-Plants: tr|I1MHT6|I1MHT6_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0212500
Domains
17
LotjaGi6g1v0212500.3
– Regulator of nonsense transcripts 2; TAIR: AT2G39260.1 regulator of nonsense transcripts UPF2; Swiss-Prot: sp|F4IUX6|RENT2_ARATH Regulator of nonsense transcripts UPF2; TrEMBL-Plants: tr|I1MHT6|I1MHT6_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0212500
Domains
17
LotjaGi6g1v0212500.4
– Regulator of nonsense transcripts 2; TAIR: AT2G39260.1 regulator of nonsense transcripts UPF2; Swiss-Prot: sp|F4IUX6|RENT2_ARATH Regulator of nonsense transcripts UPF2; TrEMBL-Plants: tr|I1MHT6|I1MHT6_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0212500
Domains
15
LotjaGi6g1v0212500.5
– Regulator of nonsense transcripts 2; TAIR: AT2G39260.1 regulator of nonsense transcripts UPF2; Swiss-Prot: sp|F4IUX6|RENT2_ARATH Regulator of nonsense transcripts UPF2; TrEMBL-Plants: tr|I1MHT6|I1MHT6_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0212500
Domains
17
LotjaGi6g1v0212500.6
– Regulator of nonsense transcripts 2; TAIR: AT2G39260.1 regulator of nonsense transcripts UPF2; Swiss-Prot: sp|F4IUX6|RENT2_ARATH Regulator of nonsense transcripts UPF2; TrEMBL-Plants: tr|I1MHT6|I1MHT6_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0212500
Domains
15
LotjaGi6g1v0212500.7
– Regulator of nonsense transcripts 2; TAIR: AT2G39260.1 regulator of nonsense transcripts UPF2; Swiss-Prot: sp|F4IUX6|RENT2_ARATH Regulator of nonsense transcripts UPF2; TrEMBL-Plants: tr|I1MHT6|I1MHT6_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0212500
Domains
17
LotjaGi6g1v0212500.8
– Regulator of nonsense transcripts 2; TAIR: AT2G39260.1 regulator of nonsense transcripts UPF2; Swiss-Prot: sp|F4IUX6|RENT2_ARATH Regulator of nonsense transcripts UPF2; TrEMBL-Plants: tr|I1MHT6|I1MHT6_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0212500
Domains
17

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 12.50