Your browser is unable to support new features implemented in HTML5 and CSS3 to render this site as intended. Your experience may suffer from functionality degradation but the site should remain usable. We strongly recommend the latest version of Google Chrome, OS X Safari or Mozilla Firefox. As Safari is bundled with OS X, if you are unable to upgrade to a newer version of OS X, we recommend using an open source browser. Dismiss message

GO:0000184

Overview

Field Value
Namespace Biological process
Short description Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
Full defintion The nonsense-mediated decay pathway for nuclear-transcribed mRNAs degrades mRNAs in which an amino-acid codon has changed to a nonsense codon; this prevents the translation of such mRNAs into truncated, and potentially harmful, proteins.
Subterm of

Relationships

The relationship of GO:0000184 with other GO terms.

Relationship type GO terms
Is a
Regulates n.a.
Part of n.a.
Positively regulates n.a.
Negatively regulates n.a.

Ancestor tree

A force layout showing the ancestor tree for GO:0000184, and its immediate children. If you wish to explore the tree dynamically, please use the GO Explorer.

  • Drag and drop nodes to manually position (i.e. fix) them
  • Double click on a node to unfix the node
  • Press Alt and double click to visit the page containing further details of a GO term
  • Right clicking on a node will reveal a context menu

Controls

Force layout

Every force layout is different—we have picked a set of parameters which suits most GO ancestor tree chart well. If you mess something up—don't worry: hitting the "reset view" button above will reset the chart to its default layout.

Additional data

This table contains additional metadata associated with the GO entry's definition field.

Field Value
GOCma
PMID
A perfect message: RNA surveillance and nonsense-mediated decay.
Cell. ; 96 (3): 307–10.PMID: 10025395

Associated Lotus transcripts 17

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

Transcript Name Description GO terms GO count
Uncharacterized protein isoform 1 [Theobroma cacao] gi|508786429|gb|EOY33685.1| 1
PREDICTED: regulator of nonsense transcripts 1 homolog isoform X2 [Cicer arietinum] gi|502160480|ref|XP_004511759.1| 6
Uncharacterized protein isoform 1 [Theobroma cacao] gi|508786429|gb|EOY33685.1| 1
Regulator of nonsense transcripts 1-like protein; TAIR: AT5G47010.1 RNA helicase; Swiss-Prot: sp|Q9FJR0|RENT1_ARATH Regulator of nonsense transcripts 1 homolog; TrEMBL-Plants: tr|I1J9N5|I1J9N5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0417100 6
TIR-NBS-LRR class disease resistance protein; TAIR: AT5G18370.1 disease resistance protein (TIR-NBS-LRR class) family protein; Swiss-Prot: sp|Q5PQS6|SMG9_RAT Protein SMG9; TrEMBL-Plants: tr|V7CID3|V7CID3_PHAVU Uncharacterized protein; Found in the gene: LotjaGi2g1v0449700 1
Protein SMG8; TAIR: AT1G01550.1 BPS1-like protein (DUF793); Swiss-Prot: sp|A1A4J7|SMG8_BOVIN Protein SMG8; TrEMBL-Plants: tr|K7M344|K7M344_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0169100 1
Regulator of nonsense transcripts UPF3 protein; TAIR: AT1G33980.1 Smg-4/UPF3 family protein; Swiss-Prot: sp|Q9FVW4|RENT3_ARATH Regulator of nonsense transcripts UPF3; TrEMBL-Plants: tr|A0A151RFI8|A0A151RFI8_CAJCA Regulator of nonsense transcripts 3A; Found in the gene: LotjaGi3g1v0336800 1
Serine/threonine-protein kinase; TAIR: AT1G50030.1 target of rapamycin; Swiss-Prot: sp|Q8BKX6|SMG1_MOUSE Serine/threonine-protein kinase SMG1; TrEMBL-Plants: tr|K7LPC3|K7LPC3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0502700 3
TIR-NBS-LRR class disease resistance protein; TAIR: AT5G18370.1 disease resistance protein (TIR-NBS-LRR class) family protein; Swiss-Prot: sp|Q5PQS6|SMG9_RAT Protein SMG9; TrEMBL-Plants: tr|V7CID3|V7CID3_PHAVU Uncharacterized protein; Found in the gene: LotjaGi6g1v0175200 1
Regulator of nonsense transcripts 2; TAIR: AT2G39260.1 regulator of nonsense transcripts UPF2; Swiss-Prot: sp|F4IUX6|RENT2_ARATH Regulator of nonsense transcripts UPF2; TrEMBL-Plants: tr|I1MHT6|I1MHT6_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0212500 1
Regulator of nonsense transcripts 2; TAIR: AT2G39260.1 regulator of nonsense transcripts UPF2; Swiss-Prot: sp|F4IUX6|RENT2_ARATH Regulator of nonsense transcripts UPF2; TrEMBL-Plants: tr|I1MHT6|I1MHT6_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0212500 1
Regulator of nonsense transcripts 2; TAIR: AT2G39260.1 regulator of nonsense transcripts UPF2; Swiss-Prot: sp|F4IUX6|RENT2_ARATH Regulator of nonsense transcripts UPF2; TrEMBL-Plants: tr|I1MHT6|I1MHT6_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0212500 1
Regulator of nonsense transcripts 2; TAIR: AT2G39260.1 regulator of nonsense transcripts UPF2; Swiss-Prot: sp|F4IUX6|RENT2_ARATH Regulator of nonsense transcripts UPF2; TrEMBL-Plants: tr|I1MHT6|I1MHT6_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0212500 1
Regulator of nonsense transcripts 2; TAIR: AT2G39260.1 regulator of nonsense transcripts UPF2; Swiss-Prot: sp|F4IUX6|RENT2_ARATH Regulator of nonsense transcripts UPF2; TrEMBL-Plants: tr|I1MHT6|I1MHT6_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0212500 1
Regulator of nonsense transcripts 2; TAIR: AT2G39260.1 regulator of nonsense transcripts UPF2; Swiss-Prot: sp|F4IUX6|RENT2_ARATH Regulator of nonsense transcripts UPF2; TrEMBL-Plants: tr|I1MHT6|I1MHT6_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0212500 1
Regulator of nonsense transcripts 2; TAIR: AT2G39260.1 regulator of nonsense transcripts UPF2; Swiss-Prot: sp|F4IUX6|RENT2_ARATH Regulator of nonsense transcripts UPF2; TrEMBL-Plants: tr|I1MHT6|I1MHT6_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0212500 1
Regulator of nonsense transcripts 2; TAIR: AT2G39260.1 regulator of nonsense transcripts UPF2; Swiss-Prot: sp|F4IUX6|RENT2_ARATH Regulator of nonsense transcripts UPF2; TrEMBL-Plants: tr|I1MHT6|I1MHT6_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0212500 1

Co-occuring GO terms 1

A list of co-occurring GO terms within the L. japonicus gene space:

GO term Namespace Name Observations Saturation (%)
Biological process Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 1 5.88