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IPR003890 is a MIF4G-like, type 3.
<p>MIF4G stands for middle domain of eukaryotic initiation factor 4G (eIF4G). eIF4G is a component of the translation initiation factor eIF4F complex and the cytoplasmic cap-binding protein complex (CBC). In the cytoplasm, cap binding complexes, distinct in their composition from nuclear cap-binding complexes, have important roles in the initiation of mRNA translation.</p> <p>The MIF4G domain also occurs in other proteins, including CBP80, a component of the nuclear CBC and NMD2, involved in the cytoplasmic nonsense-mediated mRNA decay. The domain is rich in α-helices and may contain multiple α-helical repeats. In eIF4G, this domain binds to the two other components of the eIF4F complex, eIF4A and eIF3E, and to RNA and DNA [[cite:PUB00019825]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
GO term | Namespace | Name | Definition | Relationships |
---|---|---|---|---|
Molecular function | RNA binding | Interacting selectively and non-covalently with an RNA molecule or a portion thereof. | ||
Molecular function | Protein binding | Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). |
Transcript | Name | Description | Predicted domains | Domain count |
---|---|---|---|---|
– | PREDICTED: regulator of nonsense transcripts 2-like [Glycine max] gi|356556505|ref|XP_003546565.1| | 15 | ||
– | PREDICTED: eukaryotic translation initiation factor 4G-like [Glycine max] gi|356503216|ref|XP_003520407.1| | 11 | ||
– | 14 | |||
– | PREDICTED: eukaryotic translation initiation factor 4G-like [Glycine max] gi|356503216|ref|XP_003520407.1| | 11 | ||
– | PREDICTED: eukaryotic translation initiation factor 4G-like [Glycine max] gi|356503216|ref|XP_003520407.1| | 11 | ||
– | PREDICTED: nuclear cap-binding protein subunit 1-like [Glycine max] gi|356570247|ref|XP_003553301.1| | 15 | ||
– | PREDICTED: nucleolar MIF4G domain-containing protein 1-like [Glycine max] gi|356570325|ref|XP_003553340.1| | 16 | ||
– | PREDICTED: pre-mRNA-splicing factor CWC22 homolog [Cicer arietinum] gi|502165076|ref|XP_004513404.1| | 9 | ||
– | PREDICTED: eukaryotic initiation factor iso-4F subunit p82-34-like isoform 2 [Glycine max] gi|356562557|ref|XP_003549536.1| | 15 | ||
– | PREDICTED: pre-mRNA-splicing factor CWC22 homolog [Cicer arietinum] gi|502165076|ref|XP_004513404.1| | 14 | ||
– | PREDICTED: eukaryotic initiation factor iso-4F subunit p82-34-like [Glycine max] gi|356508366|ref|XP_003522928.1| | 13 | ||
– | PREDICTED: regulator of nonsense transcripts 2-like [Glycine max] gi|356556505|ref|XP_003546565.1| | 15 | ||
– | Nucleolar MIF4G domain-containing protein 1; TAIR: AT5G17930.1 MIF4G domain-containing protein / MA3 domain-containing protein; Swiss-Prot: sp|Q5C9Z4|NOM1_HUMAN Nucleolar MIF4G domain-containing protein 1; TrEMBL-Plants: tr|A0A0B2RQV2|A0A0B2RQV2_GLYSO Nucleolar MIF4G domain-containing protein 1; Found in the gene: LotjaGi1g1v0327400 | 17 | ||
– | Nucleolar MIF4G domain-containing protein 1; TAIR: AT5G17930.1 MIF4G domain-containing protein / MA3 domain-containing protein; Swiss-Prot: sp|Q5C9Z4|NOM1_HUMAN Nucleolar MIF4G domain-containing protein 1; TrEMBL-Plants: tr|A0A0B2RQV2|A0A0B2RQV2_GLYSO Nucleolar MIF4G domain-containing protein 1; Found in the gene: LotjaGi1g1v0327400 | 17 | ||
– | Nucleolar MIF4G domain-containing protein 1; TAIR: AT5G17930.1 MIF4G domain-containing protein / MA3 domain-containing protein; Swiss-Prot: sp|Q5C9Z4|NOM1_HUMAN Nucleolar MIF4G domain-containing protein 1; TrEMBL-Plants: tr|A0A1J7HJK2|A0A1J7HJK2_LUPAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0646000_LC | 16 | ||
– | Nucleolar MIF4G domain-containing protein 1; TAIR: AT5G17930.1 MIF4G domain-containing protein / MA3 domain-containing protein; Swiss-Prot: sp|Q5C9Z4|NOM1_HUMAN Nucleolar MIF4G domain-containing protein 1; TrEMBL-Plants: tr|A0A1J7HJK2|A0A1J7HJK2_LUPAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0646000_LC | 16 | ||
– | Eukaryotic translation initiation factor 4G-like protein; TAIR: AT3G60240.2 eukaryotic translation initiation factor 4G; Swiss-Prot: sp|Q76E23|IF4G_ARATH Eukaryotic translation initiation factor 4G; TrEMBL-Plants: tr|K7L149|K7L149_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0070600 | 15 | ||
– | Eukaryotic translation initiation factor 4G-like protein; TAIR: AT3G60240.2 eukaryotic translation initiation factor 4G; Swiss-Prot: sp|Q76E23|IF4G_ARATH Eukaryotic translation initiation factor 4G; TrEMBL-Plants: tr|K7L149|K7L149_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0070800 | 15 | ||
– | Eukaryotic translation initiation factor 4G; TAIR: AT3G60240.2 eukaryotic translation initiation factor 4G; Swiss-Prot: sp|Q76E23|IF4G_ARATH Eukaryotic translation initiation factor 4G; TrEMBL-Plants: tr|K7LAK0|K7LAK0_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0070800 | 15 | ||
– | Eukaryotic translation initiation factor 4G; TAIR: AT5G57870.2 MIF4G domain-containing protein / MA3 domain-containing protein; Swiss-Prot: sp|Q93ZT6|IF4G1_ARATH Eukaryotic translation initiation factor isoform 4G-1; TrEMBL-Plants: tr|I1MT11|I1MT11_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0289300 | 15 | ||
– | Pre-mRNA-splicing factor CWC22; TAIR: AT1G80930.1 MIF4G domain-containing protein / MA3 domain-containing protein; Swiss-Prot: sp|Q9VJ87|CWC22_DROME Pre-mRNA-splicing factor CWC22 homolog; TrEMBL-Plants: tr|A0A0L9VAV7|A0A0L9VAV7_PHAAN Uncharacterized protein; Found in the gene: LotjaGi6g1v0182000 | 14 | ||
– | Eukaryotic translation initiation factor 4G-like protein; TAIR: AT5G57870.2 MIF4G domain-containing protein / MA3 domain-containing protein; Swiss-Prot: sp|Q93ZT6|IF4G1_ARATH Eukaryotic translation initiation factor isoform 4G-1; TrEMBL-Plants: tr|A0A151QNR0|A0A151QNR0_CAJCA Eukaryotic initiation factor iso-4F subunit p82-34; Found in the gene: LotjaGi6g1v0201800 | 14 | ||
– | Eukaryotic translation initiation factor 4G; TAIR: AT5G57870.2 MIF4G domain-containing protein / MA3 domain-containing protein; Swiss-Prot: sp|Q93ZT6|IF4G1_ARATH Eukaryotic translation initiation factor isoform 4G-1; TrEMBL-Plants: tr|A0A151QNR0|A0A151QNR0_CAJCA Eukaryotic initiation factor iso-4F subunit p82-34; Found in the gene: LotjaGi6g1v0201800 | 14 | ||
– | Eukaryotic translation initiation factor 4G-like protein; TAIR: AT5G57870.2 MIF4G domain-containing protein / MA3 domain-containing protein; Swiss-Prot: sp|Q93ZT6|IF4G1_ARATH Eukaryotic translation initiation factor isoform 4G-1; TrEMBL-Plants: tr|A0A151QNR0|A0A151QNR0_CAJCA Eukaryotic initiation factor iso-4F subunit p82-34; Found in the gene: LotjaGi6g1v0201800 | 14 | ||
– | Eukaryotic translation initiation factor 4G-like protein; TAIR: AT5G57870.2 MIF4G domain-containing protein / MA3 domain-containing protein; Swiss-Prot: sp|Q93ZT6|IF4G1_ARATH Eukaryotic translation initiation factor isoform 4G-1; TrEMBL-Plants: tr|A0A151QNR0|A0A151QNR0_CAJCA Eukaryotic initiation factor iso-4F subunit p82-34; Found in the gene: LotjaGi6g1v0201800 | 14 | ||
– | Eukaryotic translation initiation factor 4G; TAIR: AT5G57870.2 MIF4G domain-containing protein / MA3 domain-containing protein; Swiss-Prot: sp|Q93ZT6|IF4G1_ARATH Eukaryotic translation initiation factor isoform 4G-1; TrEMBL-Plants: tr|A0A151QNR0|A0A151QNR0_CAJCA Eukaryotic initiation factor iso-4F subunit p82-34; Found in the gene: LotjaGi6g1v0201800 | 14 | ||
– | Regulator of nonsense transcripts 2; TAIR: AT2G39260.1 regulator of nonsense transcripts UPF2; Swiss-Prot: sp|F4IUX6|RENT2_ARATH Regulator of nonsense transcripts UPF2; TrEMBL-Plants: tr|I1MHT6|I1MHT6_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0212500 | 15 | ||
– | Regulator of nonsense transcripts 2; TAIR: AT2G39260.1 regulator of nonsense transcripts UPF2; Swiss-Prot: sp|F4IUX6|RENT2_ARATH Regulator of nonsense transcripts UPF2; TrEMBL-Plants: tr|I1MHT6|I1MHT6_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0212500 | 17 | ||
– | Regulator of nonsense transcripts 2; TAIR: AT2G39260.1 regulator of nonsense transcripts UPF2; Swiss-Prot: sp|F4IUX6|RENT2_ARATH Regulator of nonsense transcripts UPF2; TrEMBL-Plants: tr|I1MHT6|I1MHT6_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0212500 | 17 | ||
– | Regulator of nonsense transcripts 2; TAIR: AT2G39260.1 regulator of nonsense transcripts UPF2; Swiss-Prot: sp|F4IUX6|RENT2_ARATH Regulator of nonsense transcripts UPF2; TrEMBL-Plants: tr|I1MHT6|I1MHT6_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0212500 | 15 | ||
– | Regulator of nonsense transcripts 2; TAIR: AT2G39260.1 regulator of nonsense transcripts UPF2; Swiss-Prot: sp|F4IUX6|RENT2_ARATH Regulator of nonsense transcripts UPF2; TrEMBL-Plants: tr|I1MHT6|I1MHT6_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0212500 | 17 | ||
– | Regulator of nonsense transcripts 2; TAIR: AT2G39260.1 regulator of nonsense transcripts UPF2; Swiss-Prot: sp|F4IUX6|RENT2_ARATH Regulator of nonsense transcripts UPF2; TrEMBL-Plants: tr|I1MHT6|I1MHT6_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0212500 | 15 | ||
– | Regulator of nonsense transcripts 2; TAIR: AT2G39260.1 regulator of nonsense transcripts UPF2; Swiss-Prot: sp|F4IUX6|RENT2_ARATH Regulator of nonsense transcripts UPF2; TrEMBL-Plants: tr|I1MHT6|I1MHT6_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0212500 | 17 | ||
– | Regulator of nonsense transcripts 2; TAIR: AT2G39260.1 regulator of nonsense transcripts UPF2; Swiss-Prot: sp|F4IUX6|RENT2_ARATH Regulator of nonsense transcripts UPF2; TrEMBL-Plants: tr|I1MHT6|I1MHT6_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0212500 | 17 |
A list of co-occurring predicted domains within the L. japonicus gene space:
Predicted domain | Source | Observations | Saturation (%) |
---|---|---|---|
mobidb-lite | MobiDBLite | 1 | 2.94 |