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IPR041897 is a Integrator complex subunit 11, MBL-fold.
<p>This entry represents the MBL-fold found in integrator complex subunit 11 (INTS11 or Int11, also known as RC-68). Integrator (INT) is a metazoan-specific multisubunit, multifunctional protein complex composed of 14 subunits named Int1-Int14 (Integrator subunits). Integrator complex has been implicated in a variety of Pol II transcription events including 3' end processing of snRNA, transcription initiation, promoter-proximal pausing, termination of protein-coding transcripts, and in HVS pre-miRNA 3' end processing [[cite:PUB00045283], [cite:PUB00092061]]. INTS11 is the endonuclease subunit for INT, responsible for the cleavage reaction at the 3' end of target RNAs [[cite:PUB00092556]]. INTS11 belongs to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions [[cite:PUB00087023]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | Cleavage and polyadenylation specificity factor subunit 3; TAIR: AT2G01730.1 cleavage and polyadenylation specificity factor 73 kDa subunit-II; Swiss-Prot: sp|Q8GUU3|CPS3B_ARATH Cleavage and polyadenylation specificity factor subunit 3-II; TrEMBL-Plants: tr|A0A072VR63|A0A072VR63_MEDTR Cleavage and polyadenylation specificity factor, putative; Found in the gene: LotjaGi1g1v0255900 | 16 | ||
| – | Cleavage and polyadenylation specificity factor subunit 3; TAIR: AT2G01730.1 cleavage and polyadenylation specificity factor 73 kDa subunit-II; Swiss-Prot: sp|Q8GUU3|CPS3B_ARATH Cleavage and polyadenylation specificity factor subunit 3-II; TrEMBL-Plants: tr|A0A072VR63|A0A072VR63_MEDTR Cleavage and polyadenylation specificity factor, putative; Found in the gene: LotjaGi1g1v0255900 | 16 | ||
| – | Cleavage and polyadenylation specificity factor subunit 3; TAIR: AT2G01730.1 cleavage and polyadenylation specificity factor 73 kDa subunit-II; Swiss-Prot: sp|Q8GUU3|CPS3B_ARATH Cleavage and polyadenylation specificity factor subunit 3-II; TrEMBL-Plants: tr|A0A072VR63|A0A072VR63_MEDTR Cleavage and polyadenylation specificity factor, putative; Found in the gene: LotjaGi1g1v0255900 | 16 | ||
| – | Cleavage and polyadenylation specificity factor subunit 3; TAIR: AT2G01730.1 cleavage and polyadenylation specificity factor 73 kDa subunit-II; Swiss-Prot: sp|Q8GUU3|CPS3B_ARATH Cleavage and polyadenylation specificity factor subunit 3-II; TrEMBL-Plants: tr|A0A072VR63|A0A072VR63_MEDTR Cleavage and polyadenylation specificity factor, putative; Found in the gene: LotjaGi1g1v0255900 | 16 | ||
| – | Cleavage and polyadenylation specificity factor subunit 3; TAIR: AT2G01730.1 cleavage and polyadenylation specificity factor 73 kDa subunit-II; Swiss-Prot: sp|Q8GUU3|CPS3B_ARATH Cleavage and polyadenylation specificity factor subunit 3-II; TrEMBL-Plants: tr|V7C7J5|V7C7J5_PHAVU Uncharacterized protein; Found in the gene: LotjaGi2g1v0072300 | 16 | ||
| – | Cleavage and polyadenylation specificity factor subunit 3; TAIR: AT2G01730.1 cleavage and polyadenylation specificity factor 73 kDa subunit-II; Swiss-Prot: sp|Q8GUU3|CPS3B_ARATH Cleavage and polyadenylation specificity factor subunit 3-II; TrEMBL-Plants: tr|V7C7J5|V7C7J5_PHAVU Uncharacterized protein; Found in the gene: LotjaGi2g1v0072300 | 16 | ||
| – | Cleavage and polyadenylation specificity factor subunit 3; TAIR: AT2G01730.1 cleavage and polyadenylation specificity factor 73 kDa subunit-II; Swiss-Prot: sp|Q8GUU3|CPS3B_ARATH Cleavage and polyadenylation specificity factor subunit 3-II; TrEMBL-Plants: tr|V7C7J5|V7C7J5_PHAVU Uncharacterized protein; Found in the gene: LotjaGi5g1v0053100 | 16 | ||
| – | Cleavage and polyadenylation specificity factor subunit 3; TAIR: AT2G01730.1 cleavage and polyadenylation specificity factor 73 kDa subunit-II; Swiss-Prot: sp|Q8GUU3|CPS3B_ARATH Cleavage and polyadenylation specificity factor subunit 3-II; TrEMBL-Plants: tr|V7C7J5|V7C7J5_PHAVU Uncharacterized protein; Found in the gene: LotjaGi5g1v0053100 | 16 | ||
| – | Cleavage and polyadenylation specificity factor subunit 3; TAIR: AT2G01730.1 cleavage and polyadenylation specificity factor 73 kDa subunit-II; Swiss-Prot: sp|Q8GUU3|CPS3B_ARATH Cleavage and polyadenylation specificity factor subunit 3-II; TrEMBL-Plants: tr|V7C7J5|V7C7J5_PHAVU Uncharacterized protein; Found in the gene: LotjaGi5g1v0053100 | 16 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| cd16291 | CDD | 1 | 11.11 |