Your browser is unable to support new features implemented in HTML5 and CSS3 to render this site as intended. Your experience may suffer from functionality degradation but the site should remain usable. We strongly recommend the latest version of Google Chrome, OS X Safari or Mozilla Firefox. As Safari is bundled with OS X, if you are unable to upgrade to a newer version of OS X, we recommend using an open source browser. Dismiss message

GO:0061608

View this GO term in other databases

Overview

Field Value
Namespace Molecular function
Short description Nuclear import signal receptor activity
Full defintion Combining with a nuclear import signal (NIS) on a cargo to be transported, to mediate transport of the cargo through the nuclear pore, from the cytoplasm to the nuclear lumen. The cargo can be either a RNA or a protein.
Subterm of

Relationships

The relationship of GO:0061608 with other GO terms.

Relationship type GO terms
Is a
Regulates n.a.
Part of n.a.
Positively regulates n.a.
Negatively regulates n.a.

Ancestor tree

A force layout showing the ancestor tree for GO:0061608, and its immediate children. If you wish to explore the tree dynamically, please use the GO Explorer.

  • Drag and drop nodes to manually position (i.e. fix) them
  • Double click on a node to unfix the node
  • Press Alt and double click to visit the page containing further details of a GO term
  • Right clicking on a node will reveal a context menu

Controls

Force layout

Every force layout is different—we have picked a set of parameters which suits most GO ancestor tree chart well. If you mess something up—don't worry: hitting the "reset view" button above will reset the chart to its default layout.

Additional data

This table contains additional metadata associated with the GO entry's definition field.

Field Value
GOCvw
WikipediaNuclear_transport
PMID
The molecular mechanism for nuclear transport and its application.Kim YH, Han ME, Oh SO
Anat Cell Biol. 2017 Jun; 50 (2): 77–85.PMID: 28713609

Transportation between the cytoplasm and the nucleoplasm is critical for many physiological and pathophysiological processes including gene expression, signal transduction, and oncogenesis. So, the molecular mechanism for the transportation needs to be studied not only to understand cell physiological processes but also to develop new diagnostic and therapeutic targets. Recent progress in the research of the nuclear transportation (import and export) via nuclear pore complex and four important factors affecting nuclear transport (nucleoporins, Ran, karyopherins, and nuclear localization signals/nuclear export signals) will be discussed. Moreover, the clinical significance of nuclear transport and its application will be reviewed. This review will provide some critical insight for the molecular design of therapeutics which need to be targeted inside the nucleus.

Associated Lotus transcripts 21

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

Transcript Name Description GO terms GO count
Lj0g3v0180319.1
– PREDICTED: LOW QUALITY PROTEIN: importin subunit alpha-1-like [Glycine max] gi|356521809|ref|XP_003529543.1|
GO terms
2
Lj4g3v2283960.1
– PREDICTED: importin subunit alpha-1-like [Cicer arietinum] gi|502084941|ref|XP_004487798.1|
GO terms
4
Lj5g3v0626520.1
– PREDICTED: importin subunit alpha-2-like [Cicer arietinum] gi|502121877|ref|XP_004497474.1|
GO terms
4
Lj5g3v0626520.2
– PREDICTED: importin subunit alpha-2-like [Cicer arietinum] gi|502121877|ref|XP_004497474.1|
GO terms
4
Lj5g3v1513590.1
– PREDICTED: importin subunit alpha-1b-like isoform X1 [Cicer arietinum] gi|502117024|ref|XP_004495674.1|
GO terms
4
Lj6g3v1525950.1
– PREDICTED: importin subunit alpha-1-like [Glycine max] gi|356556046|ref|XP_003546338.1|
GO terms
4
LotjaGi4g1v0336300.1
– Importin subunit alpha; TAIR: AT4G16143.1 importin alpha isoform 2; Swiss-Prot: sp|F4JL11|IMPA2_ARATH Importin subunit alpha-2; TrEMBL-Plants: tr|I1L0U6|I1L0U6_SOYBN Importin subunit alpha; Found in the gene: LotjaGi4g1v0336300
GO terms
4
LotjaGi4g1v0336300.2
– Importin subunit alpha; TAIR: AT4G16143.1 importin alpha isoform 2; Swiss-Prot: sp|Q9SLX0|IMA1B_ORYSJ Importin subunit alpha-1b; TrEMBL-Plants: tr|A0A151SSZ8|A0A151SSZ8_CAJCA Importin subunit alpha; Found in the gene: LotjaGi4g1v0336300
GO terms
4
LotjaGi4g1v0336300.3
– Importin subunit alpha; TAIR: AT4G16143.1 importin alpha isoform 2; Swiss-Prot: sp|F4JL11|IMPA2_ARATH Importin subunit alpha-2; TrEMBL-Plants: tr|I1L0U6|I1L0U6_SOYBN Importin subunit alpha; Found in the gene: LotjaGi4g1v0336300
GO terms
4
LotjaGi4g1v0336300.4
– Importin subunit alpha; TAIR: AT3G06720.1 importin alpha isoform 1; Swiss-Prot: sp|Q9SLX0|IMA1B_ORYSJ Importin subunit alpha-1b; TrEMBL-Plants: tr|I1L0U6|I1L0U6_SOYBN Importin subunit alpha; Found in the gene: LotjaGi4g1v0336300
GO terms
4
LotjaGi5g1v0076000.1
– Importin subunit alpha; TAIR: AT5G03070.1 importin alpha isoform 9; Swiss-Prot: sp|F4KF65|IMPA9_ARATH Importin subunit alpha-9; TrEMBL-Plants: tr|A0A072VKX7|A0A072VKX7_MEDTR Importin subunit alpha; Found in the gene: LotjaGi5g1v0076000
GO terms
4
LotjaGi5g1v0228400.1
– Importin subunit alpha; TAIR: AT3G06720.1 importin alpha isoform 1; Swiss-Prot: sp|Q96321|IMPA1_ARATH Importin subunit alpha-1; TrEMBL-Plants: tr|G7I9F7|G7I9F7_MEDTR Importin subunit alpha; Found in the gene: LotjaGi5g1v0228400
GO terms
4
LotjaGi5g1v0228400.2
– Importin subunit alpha; TAIR: AT3G06720.1 importin alpha isoform 1; Swiss-Prot: sp|Q71VM4|IMA1A_ORYSJ Importin subunit alpha-1a; TrEMBL-Plants: tr|G7I9F7|G7I9F7_MEDTR Importin subunit alpha; Found in the gene: LotjaGi5g1v0228400
GO terms
2
LotjaGi5g1v0228400.3
– Importin subunit alpha; TAIR: AT3G06720.1 importin alpha isoform 1; Swiss-Prot: sp|Q96321|IMPA1_ARATH Importin subunit alpha-1; TrEMBL-Plants: tr|G7I9F7|G7I9F7_MEDTR Importin subunit alpha; Found in the gene: LotjaGi5g1v0228400
GO terms
4
LotjaGi5g1v0228400.4
– Importin subunit alpha; TAIR: AT3G06720.1 importin alpha isoform 1; Swiss-Prot: sp|Q96321|IMPA1_ARATH Importin subunit alpha-1; TrEMBL-Plants: tr|G7I9F7|G7I9F7_MEDTR Importin subunit alpha; Found in the gene: LotjaGi5g1v0228400
GO terms
4
LotjaGi5g1v0228400.5
– Importin subunit alpha; TAIR: AT3G06720.1 importin alpha isoform 1; Swiss-Prot: sp|Q71VM4|IMA1A_ORYSJ Importin subunit alpha-1a; TrEMBL-Plants: tr|G7I9F7|G7I9F7_MEDTR Importin subunit alpha; Found in the gene: LotjaGi5g1v0228400
GO terms
2
LotjaGi6g1v0255500.1
– Importin subunit alpha; TAIR: AT3G06720.1 importin alpha isoform 1; Swiss-Prot: sp|Q96321|IMPA1_ARATH Importin subunit alpha-1; TrEMBL-Plants: tr|I1MGI7|I1MGI7_SOYBN Importin subunit alpha; Found in the gene: LotjaGi6g1v0255500
GO terms
4
LotjaGi6g1v0255500.2
– Importin subunit alpha; TAIR: AT3G06720.1 importin alpha isoform 1; Swiss-Prot: sp|Q96321|IMPA1_ARATH Importin subunit alpha-1; TrEMBL-Plants: tr|I1MGI7|I1MGI7_SOYBN Importin subunit alpha; Found in the gene: LotjaGi6g1v0255500
GO terms
4
LotjaGi6g1v0255500.3
– Importin subunit alpha; TAIR: AT3G06720.1 importin alpha isoform 1; Swiss-Prot: sp|Q96321|IMPA1_ARATH Importin subunit alpha-1; TrEMBL-Plants: tr|I1MGI7|I1MGI7_SOYBN Importin subunit alpha; Found in the gene: LotjaGi6g1v0255500
GO terms
4
LotjaGi6g1v0255500.4
– Importin subunit alpha; TAIR: AT3G06720.1 importin alpha isoform 1; Swiss-Prot: sp|Q96321|IMPA1_ARATH Importin subunit alpha-1; TrEMBL-Plants: tr|I1MGI7|I1MGI7_SOYBN Importin subunit alpha; Found in the gene: LotjaGi6g1v0255500
GO terms
4
LotjaGi6g1v0255500.5
– Importin subunit alpha; TAIR: AT4G16143.1 importin alpha isoform 2; Swiss-Prot: sp|Q71VM4|IMA1A_ORYSJ Importin subunit alpha-1a; TrEMBL-Plants: tr|I1MGI7|I1MGI7_SOYBN Importin subunit alpha; Found in the gene: LotjaGi6g1v0255500
GO terms
2

Co-occuring GO terms 1

A list of co-occurring GO terms within the L. japonicus gene space:

GO term Namespace Name Observations Saturation (%)
GO:0061608
Molecular function Nuclear import signal receptor activity 1 4.76