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IPR001372 is a Dynein light chain, type 1/2.
<p>Dynein is a multisubunit microtubule-dependent motor enzyme that acts as the force generating protein of eukaryotic cilia and flagella. The cytoplasmic isoform of dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.</p> <p>Dynein is composed of a number of ATP-binding large subunits (see [interpro:IPR004273]), intermediate size subunits and small subunits. Among the small subunits, there is a family of highly conserved proteins which make up this family [[cite:PUB00002901], [cite:PUB00003701], [cite:PUB00097852]]. Proteins in this family act as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function and may play a role in changing or maintaining the spatial distribution of cytoskeletal structures. In yeast, it was identified as a component of the nuclear pore complex where it may contribute to the stable association of the Nup82 subcomplex with the nuclear pore complex [[cite:PUB00097853]].</p> <p>Both type 1 (DLC1) and 2 (DLC2) dynein light chains have a similar two-layer α-β core structure consisting of β-α(2)-β-X-β(2) [[cite:PUB00023989], [cite:PUB00037504]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Biological process | Microtubule-based process | Any cellular process that depends upon or alters the microtubule cytoskeleton, that part of the cytoskeleton comprising microtubules and their associated proteins. | ||
| Cellular component | Dynein complex | Any of several large complexes that contain two or three dynein heavy chains and several light chains, and have microtubule motor activity. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | Dynein light chain [Medicago truncatula] gi|357478003|ref|XP_003609287.1| | 7 | ||
| – | PREDICTED: dynein light chain, cytoplasmic-like [Glycine max] gi|356498709|ref|XP_003518192.1| | 8 | ||
| – | PREDICTED: dynein light chain LC6, flagellar outer arm-like [Glycine max] gi|356513084|ref|XP_003525244.1| | 4 | ||
| – | PREDICTED: dynein light chain 2, cytoplasmic-like [Cicer arietinum] gi|502155274|ref|XP_004510015.1| | 7 | ||
| – | Dynein light chain 1 cytoplasmic-like protein [Medicago truncatula] gi|357478823|ref|XP_003609697.1| | 9 | ||
| – | PREDICTED: LOW QUALITY PROTEIN: dynein light chain LC6, flagellar outer arm-like [Glycine max] gi|356543152|ref|XP_003540027.1| | 11 | ||
| – | PREDICTED: dynein light chain LC6, flagellar outer arm-like [Cicer arietinum] gi|502176825|ref|XP_004515947.1| | 7 | ||
| – | PREDICTED: dynein light chain LC6, flagellar outer arm-like [Glycine max] gi|356513084|ref|XP_003525244.1| | 7 | ||
| – | PREDICTED: probable dynein light chain-like [Cicer arietinum] gi|502081025|ref|XP_004486743.1| | 7 | ||
| – | Dynein light chain [Vicia faba] gi|66796189|dbj|BAD99112.1| | 8 | ||
| – | Dynein light chain [Medicago truncatula] gi|357478003|ref|XP_003609287.1| | 7 | ||
| – | PREDICTED: dynein light chain 2, cytoplasmic-like [Glycine max] gi|356556098|ref|XP_003546364.1| | 4 | ||
| – | Dynein light chain family protein; TAIR: AT1G52245.1 dynein light chain LC6, flagellar outer arm-like protein; Swiss-Prot: sp|Q6BZF8|DYL1_DEBHA Dynein light chain 1, cytoplasmic; TrEMBL-Plants: tr|K7L1L1|K7L1L1_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0577900 | 8 | ||
| – | Dynein light chain; TAIR: AT1G23220.1 Dynein light chain type 1 family protein; Swiss-Prot: sp|O02414|DYL1_HELCR Dynein light chain LC6, flagellar outer arm; TrEMBL-Plants: tr|A0A0L9T8D0|A0A0L9T8D0_PHAAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0066500 | 9 | ||
| – | Dynein light chain family protein; TAIR: AT1G52245.1 dynein light chain LC6, flagellar outer arm-like protein; Swiss-Prot: sp|Q94748|DYL2_SCHMA Probable dynein light chain; TrEMBL-Plants: tr|A0A059BUK3|A0A059BUK3_EUCGR Uncharacterized protein; Found in the gene: LotjaGi3g1v0017900 | 8 | ||
| – | Dynein light chain family protein; TAIR: AT1G52245.1 dynein light chain LC6, flagellar outer arm-like protein; Swiss-Prot: sp|Q94748|DYL2_SCHMA Probable dynein light chain; TrEMBL-Plants: tr|A0A059BUK3|A0A059BUK3_EUCGR Uncharacterized protein; Found in the gene: LotjaGi3g1v0017900 | 8 | ||
| – | Dynein light chain family protein; TAIR: AT4G27360.1 Dynein light chain type 1 family protein; Swiss-Prot: sp|O02414|DYL1_HELCR Dynein light chain LC6, flagellar outer arm; TrEMBL-Plants: tr|V7AI56|V7AI56_PHAVU Uncharacterized protein; Found in the gene: LotjaGi3g1v0079200 | 12 | ||
| – | Dynein light chain family protein; TAIR: AT4G27360.1 Dynein light chain type 1 family protein; Swiss-Prot: sp|O02414|DYL1_HELCR Dynein light chain LC6, flagellar outer arm; TrEMBL-Plants: tr|I3SK05|I3SK05_LOTJA Uncharacterized protein; Found in the gene: LotjaGi3g1v0325400 | 12 | ||
| – | Dynein light chain; TAIR: AT5G20110.1 Dynein light chain type 1 family protein; Swiss-Prot: sp|O02414|DYL1_HELCR Dynein light chain LC6, flagellar outer arm; TrEMBL-Plants: tr|Q4W5W8|Q4W5W8_VICFA Dynein light chain; Found in the gene: LotjaGi4g1v0243900 | 9 | ||
| – | Dynein light chain-like protein; TAIR: AT5G20110.1 Dynein light chain type 1 family protein; Swiss-Prot: sp|Q86A88|DYL_DICDI Dynein light chain, cytoplasmic; TrEMBL-Plants: tr|G7JVC8|G7JVC8_MEDTR Dynein light chain type 1 family protein; Found in the gene: LotjaGi4g1v0269200 | 8 | ||
| – | Dynein light chain; TAIR: AT4G15930.1 Dynein light chain type 1 family protein; Swiss-Prot: sp|Q39580|DYL1_CHLRE Dynein 8 kDa light chain, flagellar outer arm; TrEMBL-Plants: tr|I3SWD9|I3SWD9_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0339200 | 11 | ||
| – | Dynein light chain; TAIR: AT1G23220.1 Dynein light chain type 1 family protein; Swiss-Prot: sp|Q86A88|DYL_DICDI Dynein light chain, cytoplasmic; TrEMBL-Plants: tr|C6SVJ0|C6SVJ0_SOYBN Putative uncharacterized protein; Found in the gene: LotjaGi4g1v0455400 | 8 | ||
| – | Dynein light chain; TAIR: AT4G15930.1 Dynein light chain type 1 family protein; Swiss-Prot: sp|Q39580|DYL1_CHLRE Dynein 8 kDa light chain, flagellar outer arm; TrEMBL-Plants: tr|I1MGN0|I1MGN0_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0251500 | 11 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 4.35 |