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IPR004516

Source: InterPro

Description

IPR004516 is a Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit.

<p>This entry represents histidine-tRNA ligase (HisS or HisRS) and its paralogue, ATP phosphoribosyltransferase regulatory subunit (HisZ). Despite the significant sequential and structural similarity, HisRS and HisZ have different functions [[cite:PUB00057738]]. HisRS is a class IIa aminoacyl-tRNA synthetase (ligase), while HisZ is a regulatory subunit of the hetero-octameric ATP phosphoribosyl transferase that regulate reactions initiating histidine biosynthesis [[cite:PUB00037892], [cite:PUB00054292]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0005737
Cellular component Cytoplasm All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
Subterm of

Associated Lotus transcripts 9

Transcript Name Description Predicted domains Domain count
Lj1g3v4591200.1
– PREDICTED: histidyl-tRNA synthetase-like [Glycine max] gi|356505252|ref|XP_003521406.1|
Domains
20
Lj4g3v3112980.1
– PREDICTED: histidine--tRNA ligase-like [Cicer arietinum] gi|502122299|ref|XP_004497677.1|
Domains
23
Lj5g3v0656970.1
– PREDICTED: histidyl-tRNA synthetase-like [Glycine max] gi|356505252|ref|XP_003521406.1|
Domains
11
Lj5g3v0656990.1
– PREDICTED: histidine--tRNA ligase-like isoform X2 [Cicer arietinum] gi|502111238|ref|XP_004493995.1|
Domains
11
LotjaGi1g1v0688700.1
– Histidine--tRNA ligase; TAIR: AT3G46100.1 Histidyl-tRNA synthetase 1; Swiss-Prot: sp|O82413|SYHM_ARATH Histidine--tRNA ligase, chloroplastic/mitochondrial; TrEMBL-Plants: tr|I1JPP8|I1JPP8_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0688700
Domains
23
LotjaGi1g1v0688700.2
– Histidine--tRNA ligase; TAIR: AT3G46100.1 Histidyl-tRNA synthetase 1; Swiss-Prot: sp|O82413|SYHM_ARATH Histidine--tRNA ligase, chloroplastic/mitochondrial; TrEMBL-Plants: tr|K7KFU0|K7KFU0_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0688700
Domains
20
LotjaGi1g1v0688700.3
– Histidine--tRNA ligase; TAIR: AT3G46100.1 Histidyl-tRNA synthetase 1; Swiss-Prot: sp|O82413|SYHM_ARATH Histidine--tRNA ligase, chloroplastic/mitochondrial; TrEMBL-Plants: tr|I1JPP8|I1JPP8_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0688700
Domains
20
LotjaGi1g1v0688700.4
– Histidine--tRNA ligase; TAIR: AT3G46100.1 Histidyl-tRNA synthetase 1; Swiss-Prot: sp|O82413|SYHM_ARATH Histidine--tRNA ligase, chloroplastic/mitochondrial; TrEMBL-Plants: tr|I1JPP8|I1JPP8_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0688700
Domains
23
LotjaGi1g1v0688700.5
– Histidine--tRNA ligase; TAIR: AT3G46100.1 Histidyl-tRNA synthetase 1; Swiss-Prot: sp|O82413|SYHM_ARATH Histidine--tRNA ligase, chloroplastic/mitochondrial; TrEMBL-Plants: tr|K7KFU0|K7KFU0_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0688700
Domains
14

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 11.11