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IPR008847 is a Suppressor of forked.
<p>This domain consists of several eukaryotic suppressor of forked (Suf) like proteins. The Drosophila melanogaster suppressor of forked [Su(f)] protein shares homology with the Saccharomyces cerevisiae RNA14 protein and the 77kDa subunit of Homo sapiens cleavage stimulation factor, which are proteins involved in mRNA 3' end formation. This suggests a role for Su(f) in mRNA 3' end formation in Drosophila. The su(f) gene produces three transcripts; two of them are polyadenylated at the end of the transcription unit, and one is a truncated transcript, polyadenylated in intron 4. It is thought that su(f) plays a role in the regulation of poly(A) site utilisation and the GU-rich sequence is important for this regulation to occur [[cite:PUB00011483]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Cellular component | Nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. | ||
| Biological process | MRNA processing | Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: LOW QUALITY PROTEIN: cleavage stimulation factor subunit 3-like [Cicer arietinum] gi|502091797|ref|XP_004489637.1| | 7 | ||
| – | PREDICTED: protein RRP5 homolog [Cicer arietinum] gi|502167476|ref|XP_004514152.1| | 22 | ||
| – | PREDICTED: crooked neck-like protein 1-like [Cicer arietinum] gi|502115405|ref|XP_004495196.1| | 12 | ||
| – | Cleavage stimulation factor subunit 3; TAIR: AT1G17760.1 Tetratricopeptide repeat (TPR)-like superfamily protein; Swiss-Prot: sp|Q8GUP1|CTF77_ARATH Cleavage stimulation factor subunit 77; TrEMBL-Plants: tr|V7C004|V7C004_PHAVU Uncharacterized protein; Found in the gene: LotjaGi2g1v0090100 | 13 | ||
| – | Polyribonucleotide nucleotidyltransferase; TAIR: AT3G11964.2 RIBOSOMAL RNA PROCESSING 5; Swiss-Prot: sp|F4J8K6|RRP5_ARATH rRNA biogenesis protein RRP5; TrEMBL-Plants: tr|I1JFV5|I1JFV5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0113300 | 21 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 20.00 |