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IPR018362 is a CCAAT-binding factor, conserved site.
<p>The CCAAT-binding factor (CBFB/NF-YA) is a mammalian transcription factor that binds to a CCAAT motif in the promoters of a wide variety of genes, including type I collagen and albumin [[cite:PUB00002598]]. The factor is a heteromeric complex of A and B subunits, both of which are required for DNA-binding [[cite:PUB00004401]]. The subunits can interact in the absence of DNA-binding, conserved regions in each being important in mediating this interaction.</p> <p>The B subunit contains a region of similarity with the yeast protein HAP2 [[cite:PUB00004731]]. For the B subunit it has been suggested that the N-terminal portion of the conserved region is involved in subunit interaction and the C-terminal region involved in DNA-binding [[cite:PUB00002769]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | DNA binding | Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). | ||
| Cellular component | CCAAT-binding factor complex | A heteromeric transcription factor complex that binds to the CCAAT-box upstream of promoters; functions as both an activator and a repressor, depending on its interacting cofactors. Typically trimeric consisting of NFYA, NFYB and NFYC subunits. In Saccharomyces, it activates the transcription of genes in response to growth in a nonfermentable carbon source and consists of four known subunits: HAP2, HAP3, HAP4 and HAP5. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: nuclear transcription factor Y subunit A-3-like isoform X1 [Cicer arietinum] gi|502165192|ref|XP_004513462.1| | 9 | ||
| – | 9 | |||
| – | PREDICTED: nuclear transcription factor Y subunit A-1-like [Glycine max] gi|356566267|ref|XP_003551355.1| | 10 | ||
| – | PREDICTED: nuclear transcription factor Y subunit A-3-like [Cicer arietinum] gi|502081419|ref|XP_004486861.1| | 10 | ||
| – | PREDICTED: nuclear transcription factor Y subunit A-3-like [Cicer arietinum] gi|502081419|ref|XP_004486861.1| | 10 | ||
| – | PREDICTED: nuclear transcription factor Y subunit A-3-like isoform X1 [Cicer arietinum] gi|502156346|ref|XP_004510428.1| | 10 | ||
| – | Nuclear transcription factor Y subunit A-3 [Arachis hypogaea] gi|469609862|gb|AGH62008.1| | 9 | ||
| – | PREDICTED: nuclear transcription factor Y subunit A-1-like [Glycine max] gi|356566267|ref|XP_003551355.1| | 10 | ||
| – | Nuclear transcription factor Y subunit; TAIR: AT5G12840.2 nuclear factor Y, subunit A1; Swiss-Prot: sp|Q9LXV5|NFYA1_ARATH Nuclear transcription factor Y subunit A-1; TrEMBL-Plants: tr|K7MQE5|K7MQE5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0011200 | 10 | ||
| – | Nuclear transcription factor Y subunit; TAIR: AT1G17590.1 nuclear factor Y, subunit A8; Swiss-Prot: sp|Q93ZH2|NFYA3_ARATH Nuclear transcription factor Y subunit A-3; TrEMBL-Plants: tr|G7IS22|G7IS22_MEDTR CCAAT-binding transcription factor; Found in the gene: LotjaGi3g1v0029300 | 10 | ||
| – | Nuclear transcription factor Y subunit; TAIR: AT1G17590.1 nuclear factor Y, subunit A8; Swiss-Prot: sp|Q9LNP6|NFYA8_ARATH Nuclear transcription factor Y subunit A-8; TrEMBL-Plants: tr|G7IS22|G7IS22_MEDTR CCAAT-binding transcription factor; Found in the gene: LotjaGi3g1v0029300 | 10 | ||
| – | Nuclear transcription factor Y subunit; TAIR: AT1G72830.1 nuclear factor Y, subunit A3; Swiss-Prot: sp|Q93ZH2|NFYA3_ARATH Nuclear transcription factor Y subunit A-3; TrEMBL-Plants: tr|A0A151T9E0|A0A151T9E0_CAJCA Nuclear transcription factor Y subunit A-3; Found in the gene: LotjaGi3g1v0417600 | 10 | ||
| – | Nuclear transcription factor Y subunit; TAIR: AT1G72830.1 nuclear factor Y, subunit A3; Swiss-Prot: sp|Q93ZH2|NFYA3_ARATH Nuclear transcription factor Y subunit A-3; TrEMBL-Plants: tr|A0A151T9E0|A0A151T9E0_CAJCA Nuclear transcription factor Y subunit A-3; Found in the gene: LotjaGi3g1v0417600 | 9 | ||
| – | Nuclear transcription factor Y subunit; TAIR: AT1G30500.2 nuclear factor Y, subunit A7; Swiss-Prot: sp|Q84JP1|NFYA7_ARATH Nuclear transcription factor Y subunit A-7; TrEMBL-Plants: tr|C6TCG7|C6TCG7_SOYBN Putative uncharacterized protein; Found in the gene: LotjaGi4g1v0385700 | 9 | ||
| – | Nuclear transcription factor Y subunit; TAIR: AT5G12840.2 nuclear factor Y, subunit A1; Swiss-Prot: sp|Q9LXV5|NFYA1_ARATH Nuclear transcription factor Y subunit A-1; TrEMBL-Plants: tr|A0A0B2REF6|A0A0B2REF6_GLYSO Nuclear transcription factor Y subunit A-1; Found in the gene: LotjaGi6g1v0135700 | 10 | ||
| – | Nuclear transcription factor Y subunit; TAIR: AT1G54160.1 nuclear factor Y, subunit A5; Swiss-Prot: sp|Q9SYH4|NFYA5_ARATH Nuclear transcription factor Y subunit A-5; TrEMBL-Plants: tr|A0A0B2PSG7|A0A0B2PSG7_GLYSO Nuclear transcription factor Y subunit A-3; Found in the gene: LotjaGi6g1v0227300 | 10 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 6.25 |