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IPR001289 is a Nuclear transcription factor Y subunit A.
<p>Diverse DNA binding proteins are known to bind the CCAAT box, a common cis- acting element found in the promoter and enhancer regions of a large number of genes in eukaryotes. Amongst these proteins is one known as the CCAAT-binding factor (CBF) or nuclear transcription factor Y (NF-Y) [[cite:PUB00004401]]. CBF is a heteromeric transcription factor that consists of two different components both needed for DNA-binding.</p> <p>The HAP protein complex of yeast binds to the upstream activation site of cytochrome C iso-1 gene (CYC1) as well as other genes involved in mitochondrial electron transport and activates their expression. It also recognises the sequence CCAAT and is structurally and evolutionary related to CBF.</p> <p>The first subunit of CBF is known as CBF-A or NF-YB in vertebrates, and HAP3 in budding yeast. The second subunit is known as CBF-B or NF-YA in vertebrates and HAP2 in budding yeast. It is a protein of 265 to 350 amino-acid residues which contains a highly conserved region of about 60 residues. This region, called the 'essential core' [[cite:PUB00003675]], seems to consist of two subdomains: an N-terminal subunit-association domain and a C-terminal DNA recognition domain.</p> <p>This entry represents the NF-YA subunit.</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | DNA-binding transcription factor activity | A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons. | ||
| Biological process | Regulation of transcription, DNA-templated | Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: nuclear transcription factor Y subunit A-3-like isoform X1 [Cicer arietinum] gi|502165192|ref|XP_004513462.1| | 9 | ||
| – | 9 | |||
| – | Transcription factor CCAAT [Lotus japonicus] gi|193237557|dbj|BAG50055.1| | 8 | ||
| – | Transcription factor CCAAT [Lotus japonicus] gi|193237557|dbj|BAG50055.1| | 8 | ||
| – | PREDICTED: nuclear transcription factor Y subunit A-1-like [Glycine max] gi|356566267|ref|XP_003551355.1| | 10 | ||
| – | PREDICTED: nuclear transcription factor Y subunit A-3-like [Cicer arietinum] gi|502081419|ref|XP_004486861.1| | 10 | ||
| – | PREDICTED: nuclear transcription factor Y subunit A-3-like [Cicer arietinum] gi|502081419|ref|XP_004486861.1| | 10 | ||
| – | PREDICTED: nuclear transcription factor Y subunit A-3-like isoform X1 [Cicer arietinum] gi|502156346|ref|XP_004510428.1| | 10 | ||
| – | Nuclear transcription factor Y subunit A-3 [Arachis hypogaea] gi|469609862|gb|AGH62008.1| | 9 | ||
| – | Transcription factor CCAAT [Lotus japonicus] gi|193237567|dbj|BAG50060.1| | 8 | ||
| – | PREDICTED: nuclear transcription factor Y subunit A-1-like [Glycine max] gi|356566267|ref|XP_003551355.1| | 10 | ||
| – | Nuclear transcription factor Y subunit; TAIR: AT5G12840.2 nuclear factor Y, subunit A1; Swiss-Prot: sp|Q9LXV5|NFYA1_ARATH Nuclear transcription factor Y subunit A-1; TrEMBL-Plants: tr|K7MQE5|K7MQE5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0011200 | 10 | ||
| – | Nuclear transcription factor Y subunit; TAIR: AT5G06510.1 nuclear factor Y, subunit A10; Swiss-Prot: sp|Q8LFU0|NFYAA_ARATH Nuclear transcription factor Y subunit A-10; TrEMBL-Plants: tr|B3IX28|B3IX28_LOTJA Transcription factor CCAAT; Found in the gene: LotjaGi1g1v0738200 | 8 | ||
| – | Nuclear transcription factor Y subunit; TAIR: AT1G17590.1 nuclear factor Y, subunit A8; Swiss-Prot: sp|Q93ZH2|NFYA3_ARATH Nuclear transcription factor Y subunit A-3; TrEMBL-Plants: tr|G7IS22|G7IS22_MEDTR CCAAT-binding transcription factor; Found in the gene: LotjaGi3g1v0029300 | 10 | ||
| – | Nuclear transcription factor Y subunit; TAIR: AT1G17590.1 nuclear factor Y, subunit A8; Swiss-Prot: sp|Q9LNP6|NFYA8_ARATH Nuclear transcription factor Y subunit A-8; TrEMBL-Plants: tr|G7IS22|G7IS22_MEDTR CCAAT-binding transcription factor; Found in the gene: LotjaGi3g1v0029300 | 10 | ||
| – | Nuclear transcription factor Y subunit; TAIR: AT1G72830.1 nuclear factor Y, subunit A3; Swiss-Prot: sp|Q93ZH2|NFYA3_ARATH Nuclear transcription factor Y subunit A-3; TrEMBL-Plants: tr|A0A151T9E0|A0A151T9E0_CAJCA Nuclear transcription factor Y subunit A-3; Found in the gene: LotjaGi3g1v0417600 | 10 | ||
| – | Nuclear transcription factor Y subunit; TAIR: AT1G72830.1 nuclear factor Y, subunit A3; Swiss-Prot: sp|Q93ZH2|NFYA3_ARATH Nuclear transcription factor Y subunit A-3; TrEMBL-Plants: tr|A0A151T9E0|A0A151T9E0_CAJCA Nuclear transcription factor Y subunit A-3; Found in the gene: LotjaGi3g1v0417600 | 9 | ||
| – | Nuclear transcription factor Y subunit; TAIR: AT1G30500.2 nuclear factor Y, subunit A7; Swiss-Prot: sp|Q84JP1|NFYA7_ARATH Nuclear transcription factor Y subunit A-7; TrEMBL-Plants: tr|C6TCG7|C6TCG7_SOYBN Putative uncharacterized protein; Found in the gene: LotjaGi4g1v0385700 | 9 | ||
| – | Nuclear transcription factor Y subunit; TAIR: AT5G06510.1 nuclear factor Y, subunit A10; Swiss-Prot: sp|Q8LFU0|NFYAA_ARATH Nuclear transcription factor Y subunit A-10; TrEMBL-Plants: tr|B3IX33|B3IX33_LOTJA Transcription factor CCAAT; Found in the gene: LotjaGi5g1v0106700 | 8 | ||
| – | Nuclear transcription factor Y subunit; TAIR: AT5G12840.2 nuclear factor Y, subunit A1; Swiss-Prot: sp|Q9LXV5|NFYA1_ARATH Nuclear transcription factor Y subunit A-1; TrEMBL-Plants: tr|A0A0B2REF6|A0A0B2REF6_GLYSO Nuclear transcription factor Y subunit A-1; Found in the gene: LotjaGi6g1v0135700 | 10 | ||
| – | Nuclear transcription factor Y subunit; TAIR: AT1G54160.1 nuclear factor Y, subunit A5; Swiss-Prot: sp|Q9SYH4|NFYA5_ARATH Nuclear transcription factor Y subunit A-5; TrEMBL-Plants: tr|A0A0B2PSG7|A0A0B2PSG7_GLYSO Nuclear transcription factor Y subunit A-3; Found in the gene: LotjaGi6g1v0227300 | 10 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 4.76 |