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IPR022702 is a DNA (cytosine-5)-methyltransferase 1, replication foci domain.
<p>This domain is part of a cytosine specific DNA methyltransferase enzyme (DNMT). It functions non-catalytically to target the protein towards replication foci. This allows the DNMT1 protein to methylate the correct residues. This domain targets DMAP1 and HDAC2 to the replication foci during the S phase of mitosis. They are thought to have some importance in conversion of critical histone lysine moieties [[cite:PUB00011312]].</p> <p>A structure exists for the human cytosine specific DNA methyltransferase replication foci domain [[cite:PUB00057711]].</p>
This description is obtained from EB-eye REST.
Transcript | Name | Description | Predicted domains | Domain count |
---|---|---|---|---|
– | DNA (cytosine-5)-methyltransferase [Medicago truncatula] gi|357498929|ref|XP_003619753.1| | 10 | ||
– | PREDICTED: DNA (cytosine-5)-methyltransferase 1-like [Cicer arietinum] gi|502162869|ref|XP_004512642.1| | 5 | ||
– | Enhanced downy mildew 2 [Arabidopsis thaliana] gi|145359280|ref|NP_200350.2| | 10 | ||
– | DNA (cytosine-5)-methyltransferase [Medicago truncatula] gi|357498929|ref|XP_003619753.1| | 25 | ||
– | 11 | |||
– | Enhanced downy mildew 2, putative; TAIR: AT5G55390.1 ENHANCED DOWNY MILDEW 2; Swiss-Prot: sp|F4K3G5|EDM2_ARATH Protein ENHANCED DOWNY MILDEW 2; TrEMBL-Plants: tr|K7KBJ1|K7KBJ1_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0022500_LC | 14 | ||
– | Cytosine-specific methyltransferase; TAIR: AT5G49160.1 methyltransferase 1; Swiss-Prot: sp|P34881|DNMT1_ARATH DNA (cytosine-5)-methyltransferase 1; TrEMBL-Plants: tr|I1JXB2|I1JXB2_SOYBN Cytosine-specific methyltransferase; Found in the gene: LotjaGi2g1v0168300 | 29 | ||
– | Cytosine-specific methyltransferase; TAIR: AT5G49160.1 methyltransferase 1; Swiss-Prot: sp|P34881|DNMT1_ARATH DNA (cytosine-5)-methyltransferase 1; TrEMBL-Plants: tr|I1KCC0|I1KCC0_SOYBN Cytosine-specific methyltransferase; Found in the gene: LotjaGi2g1v0168300 | 29 | ||
– | Cytosine-specific methyltransferase; TAIR: AT5G49160.1 methyltransferase 1; Swiss-Prot: sp|P34881|DNMT1_ARATH DNA (cytosine-5)-methyltransferase 1; TrEMBL-Plants: tr|I1JXB2|I1JXB2_SOYBN Cytosine-specific methyltransferase; Found in the gene: LotjaGi3g1v0150100 | 29 | ||
– | Cytosine-specific methyltransferase; TAIR: AT5G49160.1 methyltransferase 1; Swiss-Prot: sp|P34881|DNMT1_ARATH DNA (cytosine-5)-methyltransferase 1; TrEMBL-Plants: tr|I1KCC0|I1KCC0_SOYBN Cytosine-specific methyltransferase; Found in the gene: LotjaGi3g1v0150100 | 29 | ||
– | Enhanced downy mildew 2, putative; TAIR: AT5G55390.1 ENHANCED DOWNY MILDEW 2; Swiss-Prot: sp|F4K3G5|EDM2_ARATH Protein ENHANCED DOWNY MILDEW 2; TrEMBL-Plants: tr|A0A0B2R910|A0A0B2R910_GLYSO PHD finger-containing protein; Found in the gene: LotjaGi6g1v0152000 | 11 |
A list of co-occurring predicted domains within the L. japonicus gene space:
Predicted domain | Source | Observations | Saturation (%) |
---|---|---|---|
mobidb-lite | MobiDBLite | 1 | 9.09 |