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IPR043159 is a D-galactoside/L-rhamnose binding SUEL lectin domain superfamily.
<p>The D-galactoside binding lectin purified from sea urchin (Anthocidaris crassispina) eggs exists as a disulphide-linked homodimer of two subunits; the dimeric form is essential for hemagglutination activity [[cite:PUB00006605]]. The sea urchin egg lectin (SUEL) forms a new class of lectins. Although SUEL was first isolated as a D-galactoside binding lectin, it was latter shown that it bind to L-rhamnose preferentially [[cite:PUB00006605], [cite:PUB00006606]]. L-rhamnose and D-galactose share the same hydroxyl group orientation at C2 and C4 of the pyranose ring structure.</p> <p>A cysteine-rich domain homologous to the SUEL protein has been identified in the following proteins [[cite:PUB00006607], [cite:PUB00006608], [cite:PUB00005840]]:</p> <ul><li>Plant beta-galactosidases ([ec:3.2.1.23]) (lactases).</li> <li>Mammalian latrophilin, the calcium independent receptor of alpha-latrotoxin (CIRL). The galactose-binding lectin domain is not required for alpha-latratoxin binding [[cite:PUB00005840]].</li> <li>Human lectomedin-1.</li> <li>Rhamnose-binding lectin (SAL) from catfish (Silurus asotus, Namazu) eggs. This protein is composed of three tandem repeat domains homologous to the SUEL lectin domain. All cysteine positions of each domain are completely conserved [[cite:PUB00006606]].</li> <li>The hypothetical B0457.1, F32A7.3A and F32A7.3B proteins from Caenorhabditis elegans.</li> <li>The human KIAA0821 protein.</li></ul> <p>Structurally, the rhamnose-binding lectin domain (also known as the N-terminal lectin domain, Lec) is composed of five β-strands , a single, long α-helix, and two small helical elements. The overall fold is that of a β-sandwich with two antiparallel sheets [[cite:PUB00093730]].</p>
This description is obtained from EB-eye REST.
Transcript | Name | Description | Predicted domains | Domain count |
---|---|---|---|---|
– | Beta-galactosidase; TAIR: AT5G63810.1 beta-galactosidase 10; Swiss-Prot: sp|Q5N8X6|BGAL3_ORYSJ Beta-galactosidase 3; TrEMBL-Plants: tr|A0A0B2RCT6|A0A0B2RCT6_GLYSO Beta-galactosidase 10; Found in the gene: LotjaGi1g1v0323900 | 19 | ||
– | Beta-galactosidase; TAIR: AT5G63810.1 beta-galactosidase 10; Swiss-Prot: sp|Q5N8X6|BGAL3_ORYSJ Beta-galactosidase 3; TrEMBL-Plants: tr|A0A0R0KAT4|A0A0R0KAT4_SOYBN Beta-galactosidase; Found in the gene: LotjaGi1g1v0323900 | 28 | ||
– | Beta-galactosidase; TAIR: AT2G16730.1 glycosyl hydrolase family 35 protein; Swiss-Prot: sp|Q9SCU9|BGA13_ARATH Beta-galactosidase 13; TrEMBL-Plants: tr|G7J8I0|G7J8I0_MEDTR Beta-galactosidase; Found in the gene: LotjaGi1g1v0559100 | 30 | ||
– | Beta-galactosidase; TAIR: AT2G28470.1 beta-galactosidase 8; Swiss-Prot: sp|Q9SCV4|BGAL8_ARATH Beta-galactosidase 8; TrEMBL-Plants: tr|A0A0B2S2A3|A0A0B2S2A3_GLYSO Beta-galactosidase; Found in the gene: LotjaGi2g1v0361100 | 28 | ||
– | Beta-galactosidase; TAIR: AT2G28470.1 beta-galactosidase 8; Swiss-Prot: sp|Q9SCV4|BGAL8_ARATH Beta-galactosidase 8; TrEMBL-Plants: tr|A0A0R0HHN6|A0A0R0HHN6_SOYBN Beta-galactosidase; Found in the gene: LotjaGi2g1v0361300 | 12 | ||
– | Beta-galactosidase; TAIR: AT2G28470.1 beta-galactosidase 8; Swiss-Prot: sp|Q9SCV4|BGAL8_ARATH Beta-galactosidase 8; TrEMBL-Plants: tr|A0A0B2S2A3|A0A0B2S2A3_GLYSO Beta-galactosidase; Found in the gene: LotjaGi2g1v0361300 | 28 | ||
– | Beta-galactosidase; TAIR: AT2G28470.1 beta-galactosidase 8; Swiss-Prot: sp|Q9SCV4|BGAL8_ARATH Beta-galactosidase 8; TrEMBL-Plants: tr|A0A0B2S2A3|A0A0B2S2A3_GLYSO Beta-galactosidase; Found in the gene: LotjaGi2g1v0361300 | 25 | ||
– | Beta-galactosidase; TAIR: AT2G28470.1 beta-galactosidase 8; Swiss-Prot: sp|Q9SCV4|BGAL8_ARATH Beta-galactosidase 8; TrEMBL-Plants: tr|A0A0B2S2A3|A0A0B2S2A3_GLYSO Beta-galactosidase; Found in the gene: LotjaGi2g1v0361300 | 25 | ||
– | Beta-galactosidase; TAIR: AT2G28470.1 beta-galactosidase 8; Swiss-Prot: sp|Q9SCV4|BGAL8_ARATH Beta-galactosidase 8; TrEMBL-Plants: tr|A0A0B2S2A3|A0A0B2S2A3_GLYSO Beta-galactosidase; Found in the gene: LotjaGi2g1v0361300 | 28 | ||
– | Beta-galactosidase; TAIR: AT2G28470.1 beta-galactosidase 8; Swiss-Prot: sp|Q9SCV4|BGAL8_ARATH Beta-galactosidase 8; TrEMBL-Plants: tr|A0A0B2S2A3|A0A0B2S2A3_GLYSO Beta-galactosidase; Found in the gene: LotjaGi2g1v0361300 | 21 | ||
– | Beta-galactosidase; TAIR: AT2G28470.1 beta-galactosidase 8; Swiss-Prot: sp|Q9SCV4|BGAL8_ARATH Beta-galactosidase 8; TrEMBL-Plants: tr|A0A0B2S2A3|A0A0B2S2A3_GLYSO Beta-galactosidase; Found in the gene: LotjaGi2g1v0361300 | 21 | ||
– | Beta-galactosidase; TAIR: AT4G36360.1 beta-galactosidase 3; Swiss-Prot: sp|Q9SCV9|BGAL3_ARATH Beta-galactosidase 3; TrEMBL-Plants: tr|A0A1J7H344|A0A1J7H344_LUPAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0385700 | 28 | ||
– | Beta-galactosidase; TAIR: AT5G20710.1 beta-galactosidase 7; Swiss-Prot: sp|P49676|BGAL_BRAOL Beta-galactosidase; TrEMBL-Plants: tr|A0A151UGS6|A0A151UGS6_CAJCA Beta-galactosidase; Found in the gene: LotjaGi3g1v0012300 | 29 | ||
– | Beta-galactosidase; TAIR: AT3G13750.1 beta galactosidase 1; Swiss-Prot: sp|Q9SCW1|BGAL1_ARATH Beta-galactosidase 1; TrEMBL-Plants: tr|A2Q448|A2Q448_MEDTR Beta-galactosidase; Found in the gene: LotjaGi3g1v0025600 | 30 | ||
– | Beta-galactosidase; TAIR: AT3G13750.1 beta galactosidase 1; Swiss-Prot: sp|Q9SCW1|BGAL1_ARATH Beta-galactosidase 1; TrEMBL-Plants: tr|A2Q448|A2Q448_MEDTR Beta-galactosidase; Found in the gene: LotjaGi3g1v0025600 | 30 | ||
– | Beta-galactosidase; TAIR: AT2G28470.1 beta-galactosidase 8; Swiss-Prot: sp|Q9SCV4|BGAL8_ARATH Beta-galactosidase 8; TrEMBL-Plants: tr|I1M4L7|I1M4L7_SOYBN Beta-galactosidase; Found in the gene: LotjaGi3g1v0161400 | 27 | ||
– | Beta-galactosidase; TAIR: AT2G28470.1 beta-galactosidase 8; Swiss-Prot: sp|Q9SCV4|BGAL8_ARATH Beta-galactosidase 8; TrEMBL-Plants: tr|I1M4L7|I1M4L7_SOYBN Beta-galactosidase; Found in the gene: LotjaGi3g1v0161400 | 21 | ||
– | Beta-galactosidase; TAIR: AT2G28470.1 beta-galactosidase 8; Swiss-Prot: sp|Q9SCV4|BGAL8_ARATH Beta-galactosidase 8; TrEMBL-Plants: tr|I1M4L7|I1M4L7_SOYBN Beta-galactosidase; Found in the gene: LotjaGi3g1v0161400 | 21 | ||
– | Beta-galactosidase; TAIR: AT3G13750.1 beta galactosidase 1; Swiss-Prot: sp|Q9SCW1|BGAL1_ARATH Beta-galactosidase 1; TrEMBL-Plants: tr|A0A151SHS2|A0A151SHS2_CAJCA Beta-galactosidase; Found in the gene: LotjaGi3g1v0425600 | 30 | ||
– | Beta-galactosidase; TAIR: AT2G16730.1 glycosyl hydrolase family 35 protein; Swiss-Prot: sp|Q9SCU9|BGA13_ARATH Beta-galactosidase 13; TrEMBL-Plants: tr|G7JNE5|G7JNE5_MEDTR Beta-galactosidase; Found in the gene: LotjaGi3g1v0521000 | 30 | ||
– | Beta-galactosidase; TAIR: AT4G36360.1 beta-galactosidase 3; Swiss-Prot: sp|Q9SCV9|BGAL3_ARATH Beta-galactosidase 3; TrEMBL-Plants: tr|I1JCK7|I1JCK7_SOYBN Beta-galactosidase; Found in the gene: LotjaGi4g1v0123300 | 27 | ||
– | Beta-galactosidase; TAIR: AT4G36360.1 beta-galactosidase 3; Swiss-Prot: sp|Q9SCV9|BGAL3_ARATH Beta-galactosidase 3; TrEMBL-Plants: tr|I1JCK7|I1JCK7_SOYBN Beta-galactosidase; Found in the gene: LotjaGi4g1v0123300 | 27 | ||
– | Beta-galactosidase; TAIR: AT3G13750.1 beta galactosidase 1; Swiss-Prot: sp|P48980|BGAL_SOLLC Beta-galactosidase; TrEMBL-Plants: tr|I1MSH3|I1MSH3_SOYBN Beta-galactosidase; Found in the gene: LotjaGi4g1v0309300 | 27 | ||
– | Beta-galactosidase; TAIR: AT3G13750.1 beta galactosidase 1; Swiss-Prot: sp|P48980|BGAL_SOLLC Beta-galactosidase; TrEMBL-Plants: tr|A0A0R0GTD1|A0A0R0GTD1_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0309300 | 25 | ||
– | Beta-galactosidase; TAIR: AT3G13750.1 beta galactosidase 1; Swiss-Prot: sp|P48980|BGAL_SOLLC Beta-galactosidase; TrEMBL-Plants: tr|A0A0R0FIV9|A0A0R0FIV9_SOYBN Beta-galactosidase; Found in the gene: LotjaGi4g1v0309300 | 21 | ||
– | Beta-galactosidase; TAIR: AT3G13750.1 beta galactosidase 1; Swiss-Prot: sp|P48980|BGAL_SOLLC Beta-galactosidase; TrEMBL-Plants: tr|A0A0R0FIV9|A0A0R0FIV9_SOYBN Beta-galactosidase; Found in the gene: LotjaGi4g1v0309300 | 21 | ||
– | Beta-galactosidase; TAIR: AT5G20710.1 beta-galactosidase 7; Swiss-Prot: sp|Q9SCV5|BGAL7_ARATH Beta-galactosidase 7; TrEMBL-Plants: tr|G7IYF9|G7IYF9_MEDTR Beta-galactosidase; Found in the gene: LotjaGi6g1v0080500 | 28 |
A list of co-occurring predicted domains within the L. japonicus gene space:
Predicted domain | Source | Observations | Saturation (%) |
---|---|---|---|
SignalP-noTM | SignalP_GRAM_NEGATIVE | 1 | 3.70 |