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PR01552

Source: PRINTS

Description

DNA topoisomerase VI subunit A (TOP6A) signature

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0003677
Molecular function DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
Subterm of
GO:0003918
Molecular function DNA topoisomerase type II (ATP-hydrolyzing) activity Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2.
Subterm of
GO:0005694
Cellular component Chromosome A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.
Subterm of
GO:0006265
Biological process DNA topological change The process in which a transformation is induced in the topological structure of a double-stranded DNA helix, resulting in a change in linking number.
Subterm of

Associated Lotus transcripts 4

Transcript Name Description Predicted domains Domain count
Lj5g3v0615700.1
–
Domains
9
Lj5g3v0615710.1
– PREDICTED: DNA topoisomerase 6 subunit A-like [Cicer arietinum] gi|502121820|ref|XP_004497452.1|
Domains
15
LotjaGi5g1v0072800.1
– DNA topoisomerase 6 subunit A; TAIR: AT5G02820.1 Spo11/DNA topoisomerase VI, subunit A protein; Swiss-Prot: sp|Q9LZ03|TOP6A_ARATH DNA topoisomerase 6 subunit A; TrEMBL-Plants: tr|A0A068F783|A0A068F783_LOTJA DNA topoisomerase 6 subunit A; Found in the gene: LotjaGi5g1v0072800
Domains
17
LotjaGi6g1v0346800.1
– DNA topoisomerase 6 subunit A; TAIR: AT5G02820.1 Spo11/DNA topoisomerase VI, subunit A protein; Swiss-Prot: sp|A2XFC1|TOP6A_ORYSI DNA topoisomerase 6 subunit A3; TrEMBL-Plants: tr|I1H6P7|I1H6P7_BRADI DNA topoisomerase 6 subunit A; Found in the gene: LotjaGi6g1v0346800
Domains
16

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
cd00223 CDD 1 25.00