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| Field | Value |
|---|---|
| Gene ID | LotjaGi6g1v0346800 |
| Transcript ID | LotjaGi6g1v0346800.1 |
| Lotus japonicus genome version | Gifu v1.2 |
| Description | DNA topoisomerase 6 subunit A; TAIR: AT5G02820.1 Spo11/DNA topoisomerase VI, subunit A protein; Swiss-Prot: sp|A2XFC1|TOP6A_ORYSI DNA topoisomerase 6 subunit A3; TrEMBL-Plants: tr|I1H6P7|I1H6P7_BRADI DNA topoisomerase 6 subunit A; Found in the gene: LotjaGi6g1v0346800 |
| Working Lj name | n.a. |
Genomic sequence (LjG1.1_chr6:65920949..65922689) extracted from Lotus japonicus Gifu genome v1.2.
GTTAATATCCTTTTATTCTTACATTTATATATTGTACAAATTTATTAATATATCACAATTCACATATCAGCCAAACAGAA AAAACTACCCCATCCGATTACCCACCTCTCTCACTTTCACGATTCATCGTCTTCAGCCGCACACACAGCACACTGACACT GCTGAACCCACTTTCTCCTTCGTCCGTTCGCTGGCCGCCGCTGTCACGCCGCTAGGCCGCCACTCGCGCCAGCCCTCACG CGAGTCACGCTGCCTCTGGGCCCTGGTTCGATTGCAATTCGCAGCCTCTCGTTTTTCTTTTTGTATAAACTTTCAGGTTC ATATGGACCTGTCACTTGAATACAAACCCGCACTAAATTTCGAATTCGAAAGGAAGTCCGACCAGTGGATAAAAGAGCAT GTGTCTACTTACTCGGCGAACTATGTTGAATCTTCTGCCGCGGCAGCGAAGCGCGAAATCCCTCCGCATTTAAATGAGGA AGAGTACATACAGGTTAAAATGCTCTCGCGGGATGAGGTTTTAAATAGGATCAATAATATTTTAGATGAGTTCATGACGC TGGAACAACGTACATTCAATGTTCCTTCTCGTGGCAAGCAGAATCAATTTTACAGTAAAGAACTCAGGCGGTTCATCCTC AAGAAGAAGACATTCCGACGCATATTAAAGAAGGGAAAAACAGCTTATACAGCCGTAGCCACCTTACGTGCCTTAGTAAT CATCAAGGAAGCAGTGCAGTCTGGTAAACATATCACTCTACGCGAGCTGTATTATAGTGGCATTGACACTTTCAAGAATC AAGAATCTTCTAATAGGATAGTGGGAGATATTTGTTGTATGGTTGGTTGCGCAAGGTATTGCCTCTATGTTAAGGCTTCT GAAAGAGGGAAGGTTGTGGGGAATCTGATTTTCAAAGAGGAAGATGATACATTCGATTGCACTAGAATGGGATCTGCTGC CAAATGTATTCCTGCTAATATAGAAGATTTACAAATTATATCATGTGAGGCTCATTTTATCTTGGTAGTGGAAAAAGATG CCGCGTTTGATAGACTTGTACAAAACAGGTTTTATGATAAATTTCCATCCATCATCGTGACCGGCAAGGGTCAACCGGAT CTTTCCACCCGTTTATTTATAAAAAAGTTGATTGAAAAGAAGTATCTGCCGGTCTTTGGGTTATTTGATTATGATCCTTA TGGTATGAGAATCATGTCAGTGTATAAGTATGGATCCCAAAACATGTCTTATGAAAACTTGGCGATTCCAGAAATACAGT GGCTTGGGATCAAAACGCAAGATTTTGAGAAGTATAATATACGTGAAACGTGTGGAGTAACCATGAAGGCTGTGGACAAG GATGCTGCAAGATTGCTCTTGAAGGAAAAATTCATCACGTGTAATCCAACATGGAAGTGTGCATTGGATGATATGCTCAG TAACGGGAAAAAATATGAAATCGAATCATTTAATGCCTTTGGAATCAATTTCCTAATAGAAGGGTATTTACCGGAGAAAC TTGGGGAATTGAATTTGAAAGTGTGATGCTCCGCTTCATGGTGAGCTGGTCAAGTTTTGAGTTTCTTGTGCATAGGAAAC AATTAGAAAGAGTGATGCTCCGCTTCATGTCAAGTATCTTCAGACCATGGTTGAGTGCCTTTGCGTGCTTGGAAAAGTTG CAGCTGCTGGGGCTATGATATGCTATATGTTCTTAATAATATTTTGTTTTTTGAAAGACAC
CDS sequence (LotjaGi6g1v0346800.1) extracted from Lotus japonicus Gifu v1.2 CDS.
ATGGACCTGTCACTTGAATACAAACCCGCACTAAATTTCGAATTCGAAAGGAAGTCCGACCAGTGGATAAAAGAGCATGT GTCTACTTACTCGGCGAACTATGTTGAATCTTCTGCCGCGGCAGCGAAGCGCGAAATCCCTCCGCATTTAAATGAGGAAG AGTACATACAGGTTAAAATGCTCTCGCGGGATGAGGTTTTAAATAGGATCAATAATATTTTAGATGAGTTCATGACGCTG GAACAACGTACATTCAATGTTCCTTCTCGTGGCAAGCAGAATCAATTTTACAGTAAAGAACTCAGGCGGTTCATCCTCAA GAAGAAGACATTCCGACGCATATTAAAGAAGGGAAAAACAGCTTATACAGCCGTAGCCACCTTACGTGCCTTAGTAATCA TCAAGGAAGCAGTGCAGTCTGGTAAACATATCACTCTACGCGAGCTGTATTATAGTGGCATTGACACTTTCAAGAATCAA GAATCTTCTAATAGGATAGTGGGAGATATTTGTTGTATGGTTGGTTGCGCAAGGTATTGCCTCTATGTTAAGGCTTCTGA AAGAGGGAAGGTTGTGGGGAATCTGATTTTCAAAGAGGAAGATGATACATTCGATTGCACTAGAATGGGATCTGCTGCCA AATGTATTCCTGCTAATATAGAAGATTTACAAATTATATCATGTGAGGCTCATTTTATCTTGGTAGTGGAAAAAGATGCC GCGTTTGATAGACTTGTACAAAACAGGTTTTATGATAAATTTCCATCCATCATCGTGACCGGCAAGGGTCAACCGGATCT TTCCACCCGTTTATTTATAAAAAAGTTGATTGAAAAGAAGTATCTGCCGGTCTTTGGGTTATTTGATTATGATCCTTATG GTATGAGAATCATGTCAGTGTATAAGTATGGATCCCAAAACATGTCTTATGAAAACTTGGCGATTCCAGAAATACAGTGG CTTGGGATCAAAACGCAAGATTTTGAGAAGTATAATATACGTGAAACGTGTGGAGTAACCATGAAGGCTGTGGACAAGGA TGCTGCAAGATTGCTCTTGAAGGAAAAATTCATCACGTGTAATCCAACATGGAAGTGTGCATTGGATGATATGCTCAGTA ACGGGAAAAAATATGAAATCGAATCATTTAATGCCTTTGGAATCAATTTCCTAATAGAAGGGTATTTACCGGAGAAACTT GGGGAATTGAATTTGAAAGTGTGA
Protein sequence (LotjaGi6g1v0346800.1) extracted from Lotus japonicus Gifu v1.2 Proteins.
MDLSLEYKPALNFEFERKSDQWIKEHVSTYSANYVESSAAAAKREIPPHLNEEEYIQVKMLSRDEVLNRINNILDEFMTL EQRTFNVPSRGKQNQFYSKELRRFILKKKTFRRILKKGKTAYTAVATLRALVIIKEAVQSGKHITLRELYYSGIDTFKNQ ESSNRIVGDICCMVGCARYCLYVKASERGKVVGNLIFKEEDDTFDCTRMGSAAKCIPANIEDLQIISCEAHFILVVEKDA AFDRLVQNRFYDKFPSIIVTGKGQPDLSTRLFIKKLIEKKYLPVFGLFDYDPYGMRIMSVYKYGSQNMSYENLAIPEIQW LGIKTQDFEKYNIRETCGVTMKAVDKDAARLLLKEKFITCNPTWKCALDDMLSNGKKYEIESFNAFGINFLIEGYLPEKL GELNLKV
Data for domain prediction are obtained with InterProScan, and merged with InterPro data obtained from the EB-eye REST service.
| Prediction algorithm | Identifier | Start | End | Length | E-value | InterPro ID |
|---|---|---|---|---|---|---|
| Gene3D | 51 | 186 | 136 | 1.8E-16 | ||
| PANTHER | 53 | 404 | 352 | 3.0E-107 | ||
| PANTHER | 53 | 404 | 352 | 3.0E-107 | – | |
| Coils | 63 | 83 | 21 | - | – | |
| PRINTS | 88 | 108 | 21 | 2.4E-18 | ||
| SUPERFAMILY | 123 | 402 | 280 | 5.75E-78 | ||
| Pfam | 126 | 183 | 58 | 2.6E-16 | ||
| PRINTS | 146 | 157 | 12 | 3.1E-38 | ||
| PRINTS | 154 | 171 | 18 | 2.4E-18 | ||
| PRINTS | 160 | 177 | 18 | 3.1E-38 | ||
| PRINTS | 178 | 193 | 16 | 3.1E-38 | ||
| Gene3D | 187 | 404 | 218 | 8.7E-70 | – | |
| PRINTS | 207 | 225 | 19 | 2.4E-18 | ||
| CDD | 231 | 390 | 160 | 4.1356E-57 | ||
| PRINTS | 233 | 250 | 18 | 3.1E-38 | ||
| PRINTS | 257 | 278 | 22 | 3.1E-38 | ||
| PRINTS | 263 | 283 | 21 | 2.4E-18 | ||
| PRINTS | 289 | 305 | 17 | 3.1E-38 | ||
| PRINTS | 377 | 400 | 24 | 2.4E-18 |
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Biological process | DNA catabolic process, endonucleolytic | The chemical reactions and pathways resulting in the breakdown of DNA, involving the hydrolysis of internal 3',5'-phosphodiester bonds in one or two strands of deoxyribonucleotides. | ||
| Molecular function | DNA binding | Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). | ||
| Molecular function | Catalytic activity | Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. | ||
| Molecular function | DNA topoisomerase type II (ATP-hydrolyzing) activity | Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2. | ||
| Molecular function | ATP binding | Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. | ||
| Cellular component | Chromosome | A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information. | ||
| Biological process | DNA metabolic process | Any cellular metabolic process involving deoxyribonucleic acid. This is one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides. | ||
| Biological process | DNA topological change | The process in which a transformation is induced in the topological structure of a double-stranded DNA helix, resulting in a change in linking number. | ||
| Molecular function | Endodeoxyribonuclease activity, producing 3'-phosphomonoesters | Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acids by creating internal breaks to yield 3'-phosphomonoesters. |
Expression pattern of LotjaGi6g1v0346800.1, powered by ExpAt. For advanced configuration, data transformation and export options, view expression data in the ExpAt application.
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