Description

IPR001638 is a Solute-binding protein family 3/N-terminal domain of MltF.

<p>Bacterial high affinity transport systems are involved in active transport of solutes across the cytoplasmic membrane. Most of the bacterial ABC (ATP-binding cassette) importers are composed of one or two transmembrane permease proteins, one or two nucleotide-binding proteins and a highly specific periplasmic solute-binding protein. In Gram-negative bacteria the solute-binding proteins are dissolved in the periplasm, while in archaea and Gram-positive bacteria, their solute-binding proteins are membrane-anchored lipoproteins [[cite:PUB00071938], [cite:PUB00071925]].</p> <p>On the basis of sequence similarities, the vast majority of these solute-binding proteins can be grouped [[cite:PUB00003610]] into eight families or clusters, which generally correlate with the nature of the solute bound.</p> <p>This entry represents a domain found in the solute-binding protein family 3 members from Gram-positive bacteria, Gram-negative bacteria and archaea. This domain can also be found in the N-terminal of the membrane-bound lytic murein transglycosylase F (MltF) protein. MltF is a murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product [[cite:PUB00054945]].</p> <p>Familiy 3 members include:</p> <ul><li>Histidine-binding protein (gene hisJ) of Escherichia coli and related bacteria. An homologous lipoprotein exists in Neisseria gonorrhoeae.</li> <li>Lysine/arginine/ornithine-binding proteins (LAO) (gene argT) of Escherichia coli and related bacteria are involved in the same transport system than hisJ. Both solute-binding proteins interact with a common membrane-bound receptor hisP of the binding protein dependent transport system HisQMP.</li> <li>Glutamine-binding proteins (gene glnH) of Escherichia coli and Bacillus stearothermophilus.</li> <li>Glutamate-binding protein (gene gluB) of Corynebacterium glutamicum.</li> <li>Arginine-binding proteins artI and artJ of Escherichia coli.</li> <li>Nopaline-binding protein (gene nocT) from Agrobacterium tumefaciens.</li> <li>Octopine-binding protein (gene occT) from Agrobacterium tumefaciens.</li> <li>Major cell-binding factor (CBF1) (gene: peb1A) from Campylobacter jejuni.</li> <li>Bacteroides nodosus protein aabA.</li> <li>Cyclohexadienyl/arogenate dehydratase of Pseudomonas aeruginosa, a periplasmic enzyme which forms an alternative pathway for phenylalanine biosynthesis.</li> <li>Escherichia coli L-cystine-binding protein TcyJ, previously known as protein fliY.</li> <li>Vibrio harveyi protein patH.</li> <li>Bacillus subtilis Probable ABC transporter extracellular-binding protein yckB.</li> <li>Bacillus subtilis L-cystine-binding protein TcyA, also known as yckK.</li></ul> <p>This entry also includes domains found in a number of eukaryotic proteins including Glutamate receptors, Lysine/arginine/ornithine as well as Glutamate/glutamine/aspartate/asparagine-binding periplasmic proteins.</p>

This description is obtained from EB-eye REST.

Associated GO terms

Unable to find any GO terms for the transcript with the identifier.

Associated Lotus transcripts 35

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space: