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IPR004345

Source: InterPro

Description

IPR004345 is a TB2/DP1/HVA22.

<p>This family includes members from a wide variety of eukaryotes and includes Receptor expression-enhancing proteins (REEPs), its homologues from fungi Yop1 and similar sequences from plants. REEP/DP1/Yop1 family of proteins are involved in the control of endoplasmic reticulum organisation and mutations in some members of this family are associated with inherited diseases like Hereditary spastic paraplegias (HSPs) [[cite:PUB00095230], [cite:PUB00155129]]. REEP5, also known as TB2/DP1 (deleted in polyposis) protein [[cite:PUB00155131]], plays an essential role in heart function and development by regulating the organization and function of the sarcoplasmic reticulum in cardiomyocytes [[cite:PUB00155130]]. In human is deleted in severe forms of familial adenomatous polyposis, an autosomal dominant oncological inherited disease [[cite:PUB00020410]].</p> <p>The family also includes the plant protein of known similarity to TB2/DP1, the HVA22 abscisic acid-induced protein, which is thought to be a regulatory protein [[cite:PUB00020411]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

Unable to find any GO terms for the transcript with the identifier.

Associated Lotus transcripts 39

Transcript Name Description Predicted domains Domain count
Lj0g3v0085169.1
– HVA22-like protein a [Medicago truncatula] gi|357476185|ref|XP_003608378.1|
Domains
8
Lj0g3v0280139.1
– HVA22-like protein a [Medicago truncatula] gi|357476187|ref|XP_003608379.1|
Domains
9
Lj0g3v0280139.2
– HVA22-like protein a [Medicago truncatula] gi|357476185|ref|XP_003608378.1|
Domains
3
Lj0g3v0282559.1
– PREDICTED: HVA22-like protein j-like [Cicer arietinum] gi|502122301|ref|XP_004497678.1|
Domains
4
Lj0g3v0282559.2
– PREDICTED: HVA22-like protein j-like [Cicer arietinum] gi|502122301|ref|XP_004497678.1|
Domains
8
Lj1g3v0477770.1
– PREDICTED: HVA22-like protein a-like [Glycine max] gi|356562824|ref|XP_003549668.1|
Domains
8
Lj1g3v1486360.1
– PREDICTED: HVA22-like protein e-like isoform X1 [Cicer arietinum] gi|502133318|ref|XP_004501718.1|
Domains
10
Lj1g3v4729000.1
– PREDICTED: HVA22-like protein j-like isoform X2 [Cicer arietinum] gi|502112094|ref|XP_004494238.1|
Domains
8
Lj2g3v1294210.1
– PREDICTED: HVA22-like protein c-like [Glycine max] gi|356499791|ref|XP_003518720.1|
Domains
5
Lj2g3v1779800.1
– PREDICTED: HVA22-like protein k-like [Glycine max] gi|356496777|ref|XP_003517242.1|
Domains
5
Lj4g3v0386210.1
– HVA22-like protein a [Medicago truncatula] gi|357476185|ref|XP_003608378.1|
Domains
14
Lj4g3v0386210.2
– HVA22-like protein a [Medicago truncatula] gi|357476187|ref|XP_003608379.1|
Domains
14
Lj4g3v0387230.1
– HVA22-like protein a [Medicago truncatula] gi|357476185|ref|XP_003608378.1|
Domains
14
Lj4g3v0387230.2
– HVA22-like protein a [Medicago truncatula] gi|357476187|ref|XP_003608379.1|
Domains
18
Lj4g3v0387230.3
– HVA22-like protein a [Medicago truncatula] gi|357476185|ref|XP_003608378.1|
Domains
18
Lj4g3v1634170.1
– PREDICTED: HVA22-like protein a-like [Cicer arietinum] gi|502152078|ref|XP_004508753.1|
Domains
7
Lj4g3v2895420.1
– PREDICTED: HVA22-like protein e-like isoform X2 [Cicer arietinum] gi|502133320|ref|XP_004501719.1|
Domains
8
Lj5g3v0175620.1
– PREDICTED: HVA22-like protein i-like isoform X1 [Cicer arietinum] gi|502126273|ref|XP_004499245.1|
Domains
11
Lj5g3v1807030.1
– HVA22-like protein i [Medicago truncatula] gi|357466927|ref|XP_003603748.1|
Domains
5
LotjaGi1g1v0135400.1
– HVA22-like protein; TAIR: AT1G74520.1 HVA22 homologue A; Swiss-Prot: sp|Q9S7V4|HA22A_ARATH HVA22-like protein a; TrEMBL-Plants: tr|A0A0L9UXN1|A0A0L9UXN1_PHAAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0135400
Domains
22
LotjaGi1g1v0135500.1
– HVA22-like protein; TAIR: AT2G42820.1 HVA22-like protein F; Swiss-Prot: sp|Q682H0|HA22F_ARATH HVA22-like protein f; TrEMBL-Plants: tr|A0A1J7HU40|A0A1J7HU40_LUPAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0135500
Domains
8
LotjaGi1g1v0218300.1
– HVA22-like protein; TAIR: AT1G74520.1 HVA22 homologue A; Swiss-Prot: sp|Q9S7V4|HA22A_ARATH HVA22-like protein a; TrEMBL-Plants: tr|C6SYY3|C6SYY3_SOYBN HVA22-like protein; Found in the gene: LotjaGi1g1v0218300
Domains
8
LotjaGi1g1v0336600.1
– HVA22-like protein; TAIR: AT5G50720.1 HVA22 homologue E; Swiss-Prot: sp|Q9FED2|HA22E_ARATH HVA22-like protein e; TrEMBL-Plants: tr|I3SUZ2|I3SUZ2_LOTJA HVA22-like protein; Found in the gene: LotjaGi1g1v0336600
Domains
9
LotjaGi1g1v0561000.1
– HVA22-like protein; TAIR: AT1G75700.1 HVA22-like protein G; Swiss-Prot: sp|Q9LR09|HA22G_ARATH Putative HVA22-like protein g; TrEMBL-Plants: tr|A0A067DMK3|A0A067DMK3_CITSI HVA22-like protein; Found in the gene: LotjaGi1g1v0561000
Domains
9
LotjaGi1g1v0735400.1
– HVA22-like protein; TAIR: AT2G36020.1 HVA22-like protein J; Swiss-Prot: sp|Q8GXE9|HA22J_ARATH HVA22-like protein j; TrEMBL-Plants: tr|A0A0L9U8E9|A0A0L9U8E9_PHAAN HVA22-like protein; Found in the gene: LotjaGi1g1v0735400
Domains
13
LotjaGi1g1v0735400.2
– HVA22-like protein; TAIR: AT2G36020.1 HVA22-like protein J; Swiss-Prot: sp|Q8GXE9|HA22J_ARATH HVA22-like protein j; TrEMBL-Plants: tr|A0A0L9U8E9|A0A0L9U8E9_PHAAN HVA22-like protein; Found in the gene: LotjaGi1g1v0735400
Domains
13
LotjaGi2g1v0305800.1
– HVA22-like protein; TAIR: AT1G69700.1 HVA22 homologue C; Swiss-Prot: sp|Q9S784|HA22C_ARATH HVA22-like protein c; TrEMBL-Plants: tr|I3SHV4|I3SHV4_LOTJA HVA22-like protein; Found in the gene: LotjaGi2g1v0305800
Domains
8
LotjaGi2g1v0392800.1
– HVA22-like protein; TAIR: AT4G36720.1 HVA22-like protein K; Swiss-Prot: sp|Q6NLY8|HA22K_ARATH HVA22-like protein k; TrEMBL-Plants: tr|I3S9Z7|I3S9Z7_LOTJA HVA22-like protein; Found in the gene: LotjaGi2g1v0392800
Domains
5
LotjaGi4g1v0040600.1
– HVA22-like protein; TAIR: AT1G74520.1 HVA22 homologue A; Swiss-Prot: sp|Q9S7V4|HA22A_ARATH HVA22-like protein a; TrEMBL-Plants: tr|A0A151T2F4|A0A151T2F4_CAJCA HVA22-like protein; Found in the gene: LotjaGi4g1v0040600
Domains
21
LotjaGi4g1v0040700.1
– HVA22-like protein; TAIR: AT1G74520.1 HVA22 homologue A; Swiss-Prot: sp|Q9S7V4|HA22A_ARATH HVA22-like protein a; TrEMBL-Plants: tr|I1KQX1|I1KQX1_SOYBN HVA22-like protein; Found in the gene: LotjaGi4g1v0040700
Domains
20
LotjaGi4g1v0040700.2
– HVA22-like protein; TAIR: AT1G69700.1 HVA22 homologue C; Swiss-Prot: sp|Q9S7V4|HA22A_ARATH HVA22-like protein a; TrEMBL-Plants: tr|A0A151T2F4|A0A151T2F4_CAJCA HVA22-like protein; Found in the gene: LotjaGi4g1v0040700
Domains
20
LotjaGi4g1v0040800.1
– HVA22-like protein; TAIR: AT1G74520.1 HVA22 homologue A; Swiss-Prot: sp|Q9S7V4|HA22A_ARATH HVA22-like protein a; TrEMBL-Plants: tr|G7JV31|G7JV31_MEDTR TB2/DP1, HVA22 family protein; Found in the gene: LotjaGi4g1v0040800
Domains
18
LotjaGi4g1v0123600_LC.1
– Ribonuclease H; TAIR: AT1G04625.1 Polynucleotidyl transferase, ribonuclease H-like superfamily protein; Swiss-Prot: sp|P22382|POL_SIVGB Gag-Pol polyprotein; TrEMBL-Plants: tr|V7CNL5|V7CNL5_PHAVU Uncharacterized protein; Found in the gene: LotjaGi4g1v0123600_LC
Domains
17
LotjaGi4g1v0248900.1
– HVA22-like protein; TAIR: AT1G74520.1 HVA22 homologue A; Swiss-Prot: sp|Q9S7V4|HA22A_ARATH HVA22-like protein a; TrEMBL-Plants: tr|I3S790|I3S790_LOTJA HVA22-like protein; Found in the gene: LotjaGi4g1v0248900
Domains
8
LotjaGi4g1v0418500.1
– HVA22-like protein; TAIR: AT4G24960.1 HVA22 homologue D; Swiss-Prot: sp|Q9S760|HA22D_ARATH HVA22-like protein d; TrEMBL-Plants: tr|I1KC07|I1KC07_SOYBN HVA22-like protein; Found in the gene: LotjaGi4g1v0418500
Domains
8
LotjaGi5g1v0006800.1
– HVA22-like protein; TAIR: AT5G42560.1 Abscisic acid-responsive (TB2/DP1, HVA22) family protein; Swiss-Prot: sp|Q8LE10|HA22I_ARATH HVA22-like protein i; TrEMBL-Plants: tr|A0A0S3RQG6|A0A0S3RQG6_PHAAN HVA22-like protein; Found in the gene: LotjaGi5g1v0006800
Domains
10
LotjaGi5g1v0100200.1
– HVA22-like protein; TAIR: AT2G36020.1 HVA22-like protein J; Swiss-Prot: sp|Q8GXE9|HA22J_ARATH HVA22-like protein j; TrEMBL-Plants: tr|K7LHZ7|K7LHZ7_SOYBN HVA22-like protein; Found in the gene: LotjaGi5g1v0100200
Domains
12
LotjaGi5g1v0272100.1
– HVA22-like protein; TAIR: AT5G42560.1 Abscisic acid-responsive (TB2/DP1, HVA22) family protein; Swiss-Prot: sp|Q8LE10|HA22I_ARATH HVA22-like protein i; TrEMBL-Plants: tr|G7J4Q8|G7J4Q8_MEDTR Abscisic acid-responsive (TB2/DP1, HVA22) family protein; Found in the gene: LotjaGi5g1v0272100
Domains
10
LotjaGi5g1v0272100.2
– HVA22-like protein; TAIR: AT5G42560.1 Abscisic acid-responsive (TB2/DP1, HVA22) family protein; Swiss-Prot: sp|Q8LE10|HA22I_ARATH HVA22-like protein i; TrEMBL-Plants: tr|G7J4Q8|G7J4Q8_MEDTR Abscisic acid-responsive (TB2/DP1, HVA22) family protein; Found in the gene: LotjaGi5g1v0272100
Domains
10

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 2.56