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IPR006203

Source: InterPro

Description

IPR006203 is a GHMP kinase, ATP-binding, conserved site.

<p>The galacto- ([ec:2.7.1.6]), homoserine ([ec:2.7.1.39]), mevalonate ([ec:2.7.1.36]) and phosphomevalonate ([ec:2.7.4.2]) kinases contain, in their N-terminal section, a conserved Gly/Ser-rich region which is probably involved in the binding of ATP [[cite:PUB00003676], [cite:PUB00006508]]. This group of kinases has been called 'GHMP' (from the first letter of their substrates).</p> <p>This site is also found in some diphosphomevalonate decarboxylases, which are structurally related members of the GHMP superfamily [[cite:PUB00041428]], but do not possess kinase activity.</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0005524
Molecular function ATP binding Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
Subterm of

Associated Lotus transcripts 10

Transcript Name Description Predicted domains Domain count
Lj0g3v0357339.1
– PREDICTED: galactokinase-like [Glycine max] gi|356565073|ref|XP_003550769.1|
Domains
24
Lj1g3v4942840.1
– PREDICTED: mevalonate kinase-like [Glycine max] gi|356505870|ref|XP_003521712.1|
Domains
13
Lj1g3v4943880.1
– PREDICTED: mevalonate kinase-like [Glycine max] gi|356505870|ref|XP_003521712.1|
Domains
18
Lj2g3v3413250.1
– Homoserine kinase-like [Glycine max] gi|359807161|ref|NP_001241610.1|
Domains
18
Lj4g3v2263880.1
– PREDICTED: galactokinase-like [Cicer arietinum] gi|502150796|ref|XP_004508128.1|
Domains
24
LotjaGi1g1v0000900.1
– Homoserine kinase; TAIR: AT2G17265.1 homoserine kinase; Swiss-Prot: sp|Q8L7R2|KHSE_ARATH Homoserine kinase; TrEMBL-Plants: tr|D2DKF1|D2DKF1_SOYBN Homoserine kinase; Found in the gene: LotjaGi1g1v0000900
Domains
19
LotjaGi1g1v0000900.2
– Homoserine kinase; TAIR: AT2G17265.1 homoserine kinase; Swiss-Prot: sp|Q8L7R2|KHSE_ARATH Homoserine kinase; TrEMBL-Plants: tr|D2DKF1|D2DKF1_SOYBN Homoserine kinase; Found in the gene: LotjaGi1g1v0000900
Domains
19
LotjaGi1g1v0000900.3
– Homoserine kinase; TAIR: AT2G17265.1 homoserine kinase; Swiss-Prot: sp|Q8L7R2|KHSE_ARATH Homoserine kinase; TrEMBL-Plants: tr|D2DKF1|D2DKF1_SOYBN Homoserine kinase; Found in the gene: LotjaGi1g1v0000900
Domains
19
LotjaGi4g1v0332900.1
– Galactokinase; TAIR: AT3G06580.1 Mevalonate/galactokinase family protein; Swiss-Prot: sp|Q9SEE5|GALK1_ARATH Galactokinase; TrEMBL-Plants: tr|I1MRT3|I1MRT3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0332900
Domains
26
LotjaGi6g1v0260600.1
– Galactokinase; TAIR: AT3G06580.1 Mevalonate/galactokinase family protein; Swiss-Prot: sp|Q9SEE5|GALK1_ARATH Galactokinase; TrEMBL-Plants: tr|I1MRT3|I1MRT3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0260600
Domains
26

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
TIGR00131 TIGRFAM 1 10.00