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IPR006515

Source: InterPro

Description

IPR006515 is a Polyadenylate binding protein, human types 1, 2, 3, 4.

<p>These eukaryotic proteins recognise the poly-A of mRNA and consist of four tandem RNA recognition domains at the N terminus followed by a PABP-specific domain at the C terminus. The protein is involved in the transport of mRNAs from the nucleus to the cytoplasm [[cite:PUB00007959]]. There are four paralogs in Homo sapiens (Human) which are expressed in testis [[cite:PUB00007960]], platelets ([swissprot:Q13310] [[cite:PUB00007961]]), broadly expressed ([swissprot:P11940] [[cite:PUB00007959]]) and of unknown tissue range ([swissprot:Q15097]).</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0003723
Molecular function RNA binding Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
Subterm of

Associated Lotus transcripts 11

Transcript Name Description Predicted domains Domain count
Lj0g3v0238669.1
– Poly(A)-binding protein [Medicago truncatula] gi|357465579|ref|XP_003603074.1|
Domains
17
Lj0g3v0342329.1
– PREDICTED: polyadenylate-binding protein 2-like [Glycine max] gi|356564176|ref|XP_003550332.1|
Domains
24
Lj1g3v4691700.1
– PREDICTED: probable polyadenylate-binding protein At2g36660-like [Cicer arietinum] gi|502111603|ref|XP_004494108.1|
Domains
24
Lj4g3v0620300.2
– Poly(A)-binding protein [Medicago truncatula] gi|357475273|ref|XP_003607922.1|
Domains
20
Lj4g3v0620300.3
– PREDICTED: polyadenylate-binding protein 2-like [Glycine max] gi|356499763|ref|XP_003518706.1|
Domains
21
Lj5g3v1889580.1
– PREDICTED: polyadenylate-binding protein 3-like isoform X2 [Cicer arietinum] gi|502118843|ref|XP_004496416.1|
Domains
26
LotjaGi1g1v0356800.1
– Polyadenylate-binding protein; TAIR: AT4G34110.1 poly(A) binding protein 2; Swiss-Prot: sp|P42731|PABP2_ARATH Polyadenylate-binding protein 2; TrEMBL-Plants: tr|M5XRJ2|M5XRJ2_PRUPE Polyadenylate-binding protein; Found in the gene: LotjaGi1g1v0356800
Domains
27
LotjaGi1g1v0682900.1
– Polyadenylate-binding protein; TAIR: AT2G36660.1 poly(A) binding protein 7; Swiss-Prot: sp|Q9ZQA8|PABP7_ARATH Polyadenylate-binding protein 7; TrEMBL-Plants: tr|G7L4Y5|G7L4Y5_MEDTR Polyadenylate-binding protein; Found in the gene: LotjaGi1g1v0682900
Domains
26
LotjaGi4g1v0076900.1
– Polyadenylate-binding protein; TAIR: AT1G49760.1 poly(A) binding protein 8; Swiss-Prot: sp|Q9FXA2|PABP8_ARATH Polyadenylate-binding protein 8; TrEMBL-Plants: tr|I1JE12|I1JE12_SOYBN Polyadenylate-binding protein; Found in the gene: LotjaGi4g1v0076900
Domains
27
LotjaGi5g1v0027000.1
– Polyadenylate-binding protein; TAIR: AT1G49760.1 poly(A) binding protein 8; Swiss-Prot: sp|Q9FXA2|PABP8_ARATH Polyadenylate-binding protein 8; TrEMBL-Plants: tr|A0A0B2PYJ0|A0A0B2PYJ0_GLYSO Polyadenylate-binding protein; Found in the gene: LotjaGi5g1v0027000
Domains
26
LotjaGi5g1v0285400.1
– Polyadenylate-binding protein; TAIR: AT1G71770.1 poly(A)-binding protein 5; Swiss-Prot: sp|Q05196|PABP5_ARATH Polyadenylate-binding protein 5; TrEMBL-Plants: tr|I1NH63|I1NH63_SOYBN Polyadenylate-binding protein; Found in the gene: LotjaGi5g1v0285400
Domains
26

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 9.09