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IPR010734 is a Copine, C-terminal.
<p>This represents a conserved region approximately 180 residues long within eukaryotic copines. Copines are Ca<sup>2+</sup>-dependent phospholipid-binding proteins that are thought to be involved in membrane-trafficking, and may also be involved in cell division and growth [[cite:PUB00012971]]. They were originally identified in paramecium. They are found in human and orthologues have been found in C. elegans and Arabidopsis Thaliana. None have been found in D. Melanogaster or S. Cereviciae. Phylogenetic distribution suggests that copines have been lost in some eukaryotes [[cite:PUB00081806]]. No functional properties have been assigned to the VWA domains present in copines. The members of this subgroup contain a functional MIDAS motif based on their preferential binding to magnesium and manganese. However, the MIDAS motif is not totally conserved, in most cases the MIDAS consists of the sequence DxTxS instead of the motif DxSxS that is found in most cases. The C2 domains present in copines mediate phospholipid binding [[cite:PUB00057248], [cite:PUB00081539]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: E3 ubiquitin-protein ligase RGLG2-like isoform X1 [Cicer arietinum] gi|502091422|ref|XP_004489546.1| | 5 | ||
| – | PREDICTED: E3 ubiquitin-protein ligase RGLG1-like [Glycine max] gi|356508955|ref|XP_003523218.1| | 4 | ||
| – | PREDICTED: E3 ubiquitin-protein ligase RGLG2-like [Glycine max] gi|356512040|ref|XP_003524729.1| | 4 | ||
| – | PREDICTED: E3 ubiquitin-protein ligase RGLG2-like isoform X2 [Cicer arietinum] gi|502135587|ref|XP_004502384.1| | 12 | ||
| – | PREDICTED: E3 ubiquitin-protein ligase RGLG2-like [Glycine max] gi|356556700|ref|XP_003546661.1| | 14 | ||
| – | PREDICTED: E3 ubiquitin-protein ligase RGLG1-like isoform X3 [Cicer arietinum] gi|502137082|ref|XP_004502961.1| | 17 | ||
| – | PREDICTED: E3 ubiquitin-protein ligase RGLG1-like isoform X1 [Cicer arietinum] gi|502137077|ref|XP_004502959.1| | 8 | ||
| – | PREDICTED: E3 ubiquitin-protein ligase RGLG1-like isoform X3 [Cicer arietinum] gi|502137082|ref|XP_004502961.1| | 7 | ||
| – | PREDICTED: E3 ubiquitin-protein ligase RGLG1-like isoform X3 [Cicer arietinum] gi|502137082|ref|XP_004502961.1| | 8 | ||
| – | PREDICTED: protein BONZAI 3-like [Glycine max] gi|356505898|ref|XP_003521726.1| | 18 | ||
| – | PREDICTED: protein BONZAI 3-like [Glycine max] gi|356504074|ref|XP_003520824.1| | 7 | ||
| – | PREDICTED: E3 ubiquitin-protein ligase RGLG2-like [Glycine max] gi|356528633|ref|XP_003532904.1| | 16 | ||
| – | PREDICTED: E3 ubiquitin-protein ligase RGLG2-like [Glycine max] gi|356511063|ref|XP_003524251.1| | 19 | ||
| – | PREDICTED: E3 ubiquitin-protein ligase RGLG2-like [Glycine max] gi|356511063|ref|XP_003524251.1| | 15 | ||
| – | PREDICTED: protein BONZAI 1-like [Cicer arietinum] gi|502139656|ref|XP_004503848.1| | 17 | ||
| – | E3 ubiquitin-protein ligase RGLG2-like protein; TAIR: AT5G14420.1 RING domain ligase2; Swiss-Prot: sp|Q9LY87|RGLG2_ARATH E3 ubiquitin-protein ligase RGLG2; TrEMBL-Plants: tr|V7AXG0|V7AXG0_PHAVU Uncharacterized protein; Found in the gene: LotjaGi1g1v0227600 | 18 | ||
| – | E3 Ubiquitin ligase family protein; TAIR: AT5G63970.1 Copine (Calcium-dependent phospholipid-binding protein) family; Swiss-Prot: sp|Q8RX26|RGLG3_ARATH E3 ubiquitin-protein ligase RGLG3; TrEMBL-Plants: tr|G7JC45|G7JC45_MEDTR E3 ubiquitin-protein ligase RGLG2-like protein; Found in the gene: LotjaGi1g1v0321500 | 19 | ||
| – | Copine-1; TAIR: AT1G08860.1 Calcium-dependent phospholipid-binding Copine family protein; Swiss-Prot: sp|Q5XQC7|BON3_ARATH Protein BONZAI 3; TrEMBL-Plants: tr|I1JRH5|I1JRH5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0776600 | 21 | ||
| – | E3 ubiquitin-protein ligase RGLG2; TAIR: AT5G14420.1 RING domain ligase2; Swiss-Prot: sp|Q9LY87|RGLG2_ARATH E3 ubiquitin-protein ligase RGLG2; TrEMBL-Plants: tr|A0A0L9VN29|A0A0L9VN29_PHAAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0076400 | 17 | ||
| – | E3 ubiquitin-protein ligase RGLG2; TAIR: AT5G14420.1 RING domain ligase2; Swiss-Prot: sp|Q9LY87|RGLG2_ARATH E3 ubiquitin-protein ligase RGLG2; TrEMBL-Plants: tr|A0A0L9VN29|A0A0L9VN29_PHAAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0076400 | 17 | ||
| – | E3 ubiquitin-protein ligase RGLG2; TAIR: AT1G79380.1 Ca(2)-dependent phospholipid-binding protein (Copine) family; Swiss-Prot: sp|Q9SAL0|RGLG4_ARATH E3 ubiquitin-protein ligase RGLG4; TrEMBL-Plants: tr|A0A151QXI5|A0A151QXI5_CAJCA E3 ubiquitin-protein ligase RGLG2; Found in the gene: LotjaGi3g1v0131800 | 18 | ||
| – | E3 ubiquitin-protein ligase RGLG2; TAIR: AT1G79380.1 Ca(2)-dependent phospholipid-binding protein (Copine) family; Swiss-Prot: sp|Q9SAL0|RGLG4_ARATH E3 ubiquitin-protein ligase RGLG4; TrEMBL-Plants: tr|K7MCZ5|K7MCZ5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0296000 | 15 | ||
| – | E3 ubiquitin-protein ligase RGLG2-like protein; TAIR: AT1G67800.2 Copine (Calcium-dependent phospholipid-binding protein) family; Swiss-Prot: sp|Q8LB88|RGLG5_ARATH E3 ubiquitin-protein ligase RGLG5; TrEMBL-Plants: tr|A0A072TV45|A0A072TV45_MEDTR E3 ubiquitin-protein ligase RGLG2-like protein; Found in the gene: LotjaGi4g1v0392200 | 20 | ||
| – | E3 ubiquitin-protein ligase RGLG2-like protein; TAIR: AT1G67800.2 Copine (Calcium-dependent phospholipid-binding protein) family; Swiss-Prot: sp|Q8LB88|RGLG5_ARATH E3 ubiquitin-protein ligase RGLG5; TrEMBL-Plants: tr|A0A072TV45|A0A072TV45_MEDTR E3 ubiquitin-protein ligase RGLG2-like protein; Found in the gene: LotjaGi4g1v0392200 | 20 | ||
| – | E3 ubiquitin-protein ligase RGLG2-like protein; TAIR: AT1G67800.1 Copine (Calcium-dependent phospholipid-binding protein) family; Swiss-Prot: sp|Q8LB88|RGLG5_ARATH E3 ubiquitin-protein ligase RGLG5; TrEMBL-Plants: tr|A0A0S3QYP6|A0A0S3QYP6_PHAAN Uncharacterized protein; Found in the gene: LotjaGi4g1v0392200 | 16 | ||
| – | E3 ubiquitin-protein ligase RGLG2-like protein; TAIR: AT1G67800.2 Copine (Calcium-dependent phospholipid-binding protein) family; Swiss-Prot: sp|Q8LB88|RGLG5_ARATH E3 ubiquitin-protein ligase RGLG5; TrEMBL-Plants: tr|A0A072TV45|A0A072TV45_MEDTR E3 ubiquitin-protein ligase RGLG2-like protein; Found in the gene: LotjaGi4g1v0392200 | 20 | ||
| – | E3 ubiquitin-protein ligase RGLG2-like protein; TAIR: AT1G67800.1 Copine (Calcium-dependent phospholipid-binding protein) family; Swiss-Prot: sp|Q8LB88|RGLG5_ARATH E3 ubiquitin-protein ligase RGLG5; TrEMBL-Plants: tr|A0A0S3QYP6|A0A0S3QYP6_PHAAN Uncharacterized protein; Found in the gene: LotjaGi4g1v0392200 | 16 | ||
| – | E3 ubiquitin-protein ligase RGLG2-like protein; TAIR: AT1G67800.1 Copine (Calcium-dependent phospholipid-binding protein) family; Swiss-Prot: sp|Q8LB88|RGLG5_ARATH E3 ubiquitin-protein ligase RGLG5; TrEMBL-Plants: tr|A0A0S3QYP6|A0A0S3QYP6_PHAAN Uncharacterized protein; Found in the gene: LotjaGi4g1v0392200 | 16 | ||
| – | E3 Ubiquitin ligase family protein; TAIR: AT5G63970.1 Copine (Calcium-dependent phospholipid-binding protein) family; Swiss-Prot: sp|Q8RX26|RGLG3_ARATH E3 ubiquitin-protein ligase RGLG3; TrEMBL-Plants: tr|A0A1J7HDM6|A0A1J7HDM6_LUPAN Uncharacterized protein; Found in the gene: LotjaGi4g1v0410700 | 11 | ||
| – | E3 ubiquitin-protein ligase RGLG2-like protein; TAIR: AT5G63970.1 Copine (Calcium-dependent phospholipid-binding protein) family; Swiss-Prot: sp|Q8RX26|RGLG3_ARATH E3 ubiquitin-protein ligase RGLG3; TrEMBL-Plants: tr|I1K512|I1K512_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0410700 | 16 | ||
| – | Copine-1; TAIR: AT5G61910.4 DCD (Development and Cell Death) domain protein; Swiss-Prot: sp|Q941L3|BON1_ARATH Protein BONZAI 1; TrEMBL-Plants: tr|A0A151S2L5|A0A151S2L5_CAJCA Copine-3; Found in the gene: LotjaGi4g1v0422300 | 19 | ||
| – | Copine-1; TAIR: AT5G61910.4 DCD (Development and Cell Death) domain protein; Swiss-Prot: sp|Q941L3|BON1_ARATH Protein BONZAI 1; TrEMBL-Plants: tr|A0A072U553|A0A072U553_MEDTR Calcium-dependent phospholipid-binding copine family protein; Found in the gene: LotjaGi4g1v0422300 | 7 | ||
| – | E3 ubiquitin-protein ligase RGLG2-like protein; TAIR: AT3G01650.1 RING domain ligase1; Swiss-Prot: sp|Q9SS90|RGLG1_ARATH E3 ubiquitin-protein ligase RGLG1; TrEMBL-Plants: tr|V7D004|V7D004_PHAVU Uncharacterized protein; Found in the gene: LotjaGi6g1v0095700 | 18 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 3.03 |