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IPR012990 is a Sec23/Sec24 beta-sandwich.
<p>COPII (coat protein complex II)-coated vesicles carry proteins from the endoplasmic reticulum (ER) to the Golgi complex [[cite:PUB00014931]]. COPII-coated vesicles form on the ER by the stepwise recruitment of three cytosolic components: Sar1-GTP to initiate coat formation, Sec23/24 heterodimer to select SNARE and cargo molecules, and Sec13/31 to induce coat polymerisation and membrane deformation [[cite:PUB00014933]].</p> <p>Sec23 p and Sec24p are structurally related, folding into five distinct domains: a β-barrel, a zinc-finger ([interpro:IPR006895]), an α/β trunk domain ([interpro:IPR006896]), an all-helical region ([interpro:IPR006900]), and a C-terminal gelsolin-like domain ([interpro:IPR007123]). This entry describes part of the Sec23/24 β-barrel domain, which is formed from approximately 180 residues from three segments of the polypeptide. The strands of the barrel are oriented roughly parallel to the membrane such that one end of the barrel forms part of the inner surface of the coat and the other end part of the membrane-distal surface. The barrel is constructed from two opposed sheets: a six-stranded β-sheet facing partly towards the zinc finger domain and partly towards the solvent, and a five-stranded β-sheet facing the helical domain.</p>
This description is obtained from EB-eye REST.
Transcript | Name | Description | Predicted domains | Domain count |
---|---|---|---|---|
– | PREDICTED: protein transport protein SEC23-like isoform 1 [Glycine max] gi|356540108|ref|XP_003538532.1| | 19 | ||
– | PREDICTED: protein transport protein Sec24-like At4g32640-like [Glycine max] gi|356534416|ref|XP_003535751.1| | 18 | ||
– | PREDICTED: protein transport protein SEC23-like isoform X1 [Cicer arietinum] gi|502135229|ref|XP_004502262.1| | 21 | ||
– | PREDICTED: protein transport protein SEC23-like isoform X1 [Cicer arietinum] gi|502135095|ref|XP_004502219.1| | 20 | ||
– | PREDICTED: protein transport protein SEC23-like isoform X1 [Cicer arietinum] gi|502135095|ref|XP_004502219.1| | 20 | ||
– | Protein transport protein SEC23 [Medicago truncatula] gi|357513131|ref|XP_003626854.1| | 19 | ||
– | PREDICTED: protein transport protein Sec24-like At3g07100-like [Cicer arietinum] gi|502113027|ref|XP_004494519.1| | 22 | ||
– | PREDICTED: protein transport protein Sec23A-like [Glycine max] gi|356572844|ref|XP_003554575.1| | 24 | ||
– | PREDICTED: protein transport protein Sec23A-like [Cicer arietinum] gi|502135226|ref|XP_004502261.1| | 14 | ||
– | PREDICTED: protein transport protein Sec24-like At4g32640-like [Glycine max] gi|356534416|ref|XP_003535751.1| | 23 | ||
– | Protein transport protein Sec24-like; TAIR: AT3G07100.1 Sec23/Sec24 protein transport family protein; Swiss-Prot: sp|Q9SFU0|SC24A_ARATH Protein transport protein Sec24-like At3g07100; TrEMBL-Plants: tr|I1NBN5|I1NBN5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0750200 | 28 | ||
– | Protein transport protein Sec24-like; TAIR: AT3G07100.1 Sec23/Sec24 protein transport family protein; Swiss-Prot: sp|Q9SFU0|SC24A_ARATH Protein transport protein Sec24-like At3g07100; TrEMBL-Plants: tr|I1NBN5|I1NBN5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0750200 | 28 | ||
– | Protein transport protein SEC23; TAIR: AT4G01810.1 Sec23/Sec24 protein transport family protein; Swiss-Prot: sp|Q0US25|SEC23_PHANO Protein transport protein SEC23; TrEMBL-Plants: tr|K7MZM9|K7MZM9_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0754600 | 28 | ||
– | Protein transport protein SEC23; TAIR: AT4G01810.1 Sec23/Sec24 protein transport family protein; Swiss-Prot: sp|Q0US25|SEC23_PHANO Protein transport protein SEC23; TrEMBL-Plants: tr|K7MZM9|K7MZM9_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0754600 | 28 | ||
– | Protein transport protein SEC23; TAIR: AT4G01810.1 Sec23/Sec24 protein transport family protein; Swiss-Prot: sp|Q0US25|SEC23_PHANO Protein transport protein SEC23; TrEMBL-Plants: tr|A0A151TXC4|A0A151TXC4_CAJCA Protein transport protein Sec23A; Found in the gene: LotjaGi1g1v0754600 | 28 | ||
– | Protein transport protein SEC23; TAIR: AT2G21630.1 Sec23/Sec24 protein transport family protein; Swiss-Prot: sp|Q4PE39|SEC23_USTMA Protein transport protein SEC23; TrEMBL-Plants: tr|G7LEA6|G7LEA6_MEDTR Protein transporter Sec23-like protein; Found in the gene: LotjaGi3g1v0268900 | 30 | ||
– | Protein transport protein SEC23; TAIR: AT2G21630.1 Sec23/Sec24 protein transport family protein; Swiss-Prot: sp|Q4PE39|SEC23_USTMA Protein transport protein SEC23; TrEMBL-Plants: tr|G7LEA6|G7LEA6_MEDTR Protein transporter Sec23-like protein; Found in the gene: LotjaGi3g1v0268900 | 30 | ||
– | Protein transport protein SEC23; TAIR: AT1G05520.1 Sec23/Sec24 protein transport family protein; Swiss-Prot: sp|Q4PE39|SEC23_USTMA Protein transport protein SEC23; TrEMBL-Plants: tr|A0A1J7GI99|A0A1J7GI99_LUPAN Uncharacterized protein; Found in the gene: LotjaGi4g1v0368900 | 30 | ||
– | Protein transport protein SEC23; TAIR: AT1G05520.1 Sec23/Sec24 protein transport family protein; Swiss-Prot: sp|Q4PE39|SEC23_USTMA Protein transport protein SEC23; TrEMBL-Plants: tr|A0A1J7GI99|A0A1J7GI99_LUPAN Uncharacterized protein; Found in the gene: LotjaGi4g1v0368900 | 28 | ||
– | Protein transport protein Sec24-like family; TAIR: AT4G32640.1 Sec23/Sec24 protein transport family protein; Swiss-Prot: sp|Q9M081|SC24B_ARATH Protein transport protein Sec24-like At4g32640; TrEMBL-Plants: tr|A0A151TQ51|A0A151TQ51_CAJCA Protein transport protein Sec24-like family; Found in the gene: LotjaGi5g1v0346900 | 30 | ||
– | Protein transport protein Sec24-like family; TAIR: AT4G32640.1 Sec23/Sec24 protein transport family protein; Swiss-Prot: sp|Q9M081|SC24B_ARATH Protein transport protein Sec24-like At4g32640; TrEMBL-Plants: tr|A0A151TQ51|A0A151TQ51_CAJCA Protein transport protein Sec24-like family; Found in the gene: LotjaGi5g1v0346900 | 30 | ||
– | Protein transport protein Sec24-like family; TAIR: AT3G44340.1 hypothetical protein; Swiss-Prot: sp|Q9M291|SC24C_ARATH Protein transport protein Sec24-like CEF; TrEMBL-Plants: tr|A0A151TQ51|A0A151TQ51_CAJCA Protein transport protein Sec24-like family; Found in the gene: LotjaGi5g1v0346900 | 24 | ||
– | Protein transport protein SEC23; TAIR: AT5G43670.1 Sec23/Sec24 protein transport family protein; Swiss-Prot: sp|Q4PE39|SEC23_USTMA Protein transport protein SEC23; TrEMBL-Plants: tr|G8A123|G8A123_MEDTR Protein transporter Sec23-like protein; Found in the gene: LotjaGi6g1v0038800 | 30 | ||
– | Protein transport protein SEC23; TAIR: AT1G05520.1 Sec23/Sec24 protein transport family protein; Swiss-Prot: sp|Q4PE39|SEC23_USTMA Protein transport protein SEC23; TrEMBL-Plants: tr|G7JBC0|G7JBC0_MEDTR Protein transporter Sec23-like protein; Found in the gene: LotjaGi6g1v0103600 | 31 |
A list of co-occurring predicted domains within the L. japonicus gene space:
Predicted domain | Source | Observations | Saturation (%) |
---|---|---|---|
cd11287 | CDD | 1 | 4.17 |