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IPR007123

Source: InterPro

Description

IPR007123 is a Gelsolin-like domain.

<p>Gelsolin is a cytoplasmic, calcium-regulated, actin-modulating protein that binds to the barbed ends of actin filaments, preventing monomer exchange (end-blocking or capping) [[cite:PUB00001347]]. It can promote nucleation (the assembly of monomers into filaments), as well as sever existing filaments. In addition, this protein binds with high affinity to fibronectin. Plasma gelsolin and cytoplasmic gelsolin are derived from a single gene by alternate initiation sites and differential splicing.</p> <p>Sequence comparisons indicate an evolutionary relationship between gelsolin, villin, fragmin and severin [[cite:PUB00003232]]. Six large repeating segments occur in gelsolin and villin, and 3 similar segments in severin and fragmin. While the multiple repeats have yet to be related to any known function of the actin-severing proteins, the superfamily appears to have evolved from an ancestral sequence of 120 to 130 amino acid residues [[cite:PUB00003232]].</p> <p>This gelsolin-like domain can also be found in the C-terminal of the members of Sec23/Sec24 family. They are components of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER).</p>

This description is obtained from EB-eye REST.

Associated GO terms

Unable to find any GO terms for the transcript with the identifier.

Associated Lotus transcripts 47

Transcript Name Description Predicted domains Domain count
Lj0g3v0011199.1
– PREDICTED: villin-2-like [Glycine max] gi|356500511|ref|XP_003519075.1|
Domains
15
Lj0g3v0011199.3
– PREDICTED: villin-2-like isoform 1 [Glycine max] gi|356534770|ref|XP_003535925.1|
Domains
19
Lj0g3v0114229.1
– PREDICTED: villin-3-like [Cicer arietinum] gi|502166332|ref|XP_004513861.1|
Domains
11
Lj0g3v0114239.1
– PREDICTED: villin-2-like [Solanum lycopersicum] gi|460408618|ref|XP_004249740.1|
Domains
12
Lj0g3v0201099.1
– PREDICTED: protein transport protein SEC23-like isoform 1 [Glycine max] gi|356540108|ref|XP_003538532.1|
Domains
19
Lj0g3v0222659.1
– PREDICTED: protein transport protein SEC23-like [Glycine max] gi|356504446|ref|XP_003521007.1|
Domains
11
Lj0g3v0242929.1
– PREDICTED: protein transport protein SEC23-like isoform X1 [Cicer arietinum] gi|502135229|ref|XP_004502262.1|
Domains
21
Lj0g3v0258459.1
– PREDICTED: villin-2-like isoform 1 [Glycine max] gi|356534770|ref|XP_003535925.1|
Domains
19
Lj0g3v0258459.3
– PREDICTED: villin-2-like isoform 2 [Glycine max] gi|356534772|ref|XP_003535926.1|
Domains
12
Lj0g3v0266789.1
– PREDICTED: villin-4-like [Glycine max] gi|356530312|ref|XP_003533726.1|
Domains
16
Lj0g3v0332229.1
– PREDICTED: protein transport protein SEC23-like isoform X1 [Cicer arietinum] gi|502135095|ref|XP_004502219.1|
Domains
20
Lj0g3v0332229.2
– PREDICTED: protein transport protein SEC23-like isoform X1 [Cicer arietinum] gi|502135095|ref|XP_004502219.1|
Domains
20
Lj0g3v0338629.1
– PREDICTED: villin-4-like isoform 1 [Glycine max] gi|356556212|ref|XP_003546420.1|
Domains
12
Lj1g3v4241150.1
– PREDICTED: villin-2-like isoform X5 [Cicer arietinum] gi|502108740|ref|XP_004493490.1|
Domains
16
Lj1g3v4804040.1
– PREDICTED: protein transport protein Sec24-like At3g07100-like [Cicer arietinum] gi|502113027|ref|XP_004494519.1|
Domains
22
Lj1g3v4830280.1
– PREDICTED: protein transport protein Sec23A-like [Glycine max] gi|356572844|ref|XP_003554575.1|
Domains
24
Lj4g3v2576080.1
– PREDICTED: protein transport protein Sec23A-like [Cicer arietinum] gi|502135226|ref|XP_004502261.1|
Domains
14
Lj5g3v2241210.2
– PREDICTED: protein transport protein Sec24-like At4g32640-like [Glycine max] gi|356534416|ref|XP_003535751.1|
Domains
23
LotjaGi1g1v0672500.1
– Villin; TAIR: AT2G41740.1 villin 2; Swiss-Prot: sp|O81644|VILI2_ARATH Villin-2; TrEMBL-Plants: tr|A0A0S3RXC8|A0A0S3RXC8_PHAAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0672500
Domains
25
LotjaGi1g1v0672500.2
– Villin; TAIR: AT2G41740.1 villin 2; Swiss-Prot: sp|O81644|VILI2_ARATH Villin-2; TrEMBL-Plants: tr|A0A1J7I9H4|A0A1J7I9H4_LUPAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0672500
Domains
23
LotjaGi1g1v0672500.3
– Villin; TAIR: AT2G41740.1 villin 2; Swiss-Prot: sp|O81644|VILI2_ARATH Villin-2; TrEMBL-Plants: tr|A0A1J7I9H4|A0A1J7I9H4_LUPAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0672500
Domains
22
LotjaGi1g1v0672500.4
– Villin; TAIR: AT2G41740.1 villin 2; Swiss-Prot: sp|O81644|VILI2_ARATH Villin-2; TrEMBL-Plants: tr|G7KTI5|G7KTI5_MEDTR Villin; Found in the gene: LotjaGi1g1v0672500
Domains
25
LotjaGi1g1v0672500.5
– Villin; TAIR: AT2G41740.1 villin 2; Swiss-Prot: sp|O81644|VILI2_ARATH Villin-2; TrEMBL-Plants: tr|A0A0S3RXC8|A0A0S3RXC8_PHAAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0672500
Domains
17
LotjaGi1g1v0672500.6
– Villin; TAIR: AT2G41740.1 villin 2; Swiss-Prot: sp|O81644|VILI2_ARATH Villin-2; TrEMBL-Plants: tr|A0A0S3RXC8|A0A0S3RXC8_PHAAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0672500
Domains
25
LotjaGi3g1v0268900.2
– Protein transport protein SEC23; TAIR: AT2G21630.1 Sec23/Sec24 protein transport family protein; Swiss-Prot: sp|Q4PE39|SEC23_USTMA Protein transport protein SEC23; TrEMBL-Plants: tr|G7LEA6|G7LEA6_MEDTR Protein transporter Sec23-like protein; Found in the gene: LotjaGi3g1v0268900
Domains
30
LotjaGi3g1v0268900.3
– Protein transport protein SEC23; TAIR: AT2G21630.1 Sec23/Sec24 protein transport family protein; Swiss-Prot: sp|Q4PE39|SEC23_USTMA Protein transport protein SEC23; TrEMBL-Plants: tr|G7LEA6|G7LEA6_MEDTR Protein transporter Sec23-like protein; Found in the gene: LotjaGi3g1v0268900
Domains
30
LotjaGi4g1v0303900.1
– Villin; TAIR: AT4G30160.1 villin 4; Swiss-Prot: sp|O65570|VILI4_ARATH Villin-4; TrEMBL-Plants: tr|K7LWU7|K7LWU7_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0303900
Domains
27
LotjaGi4g1v0303900.2
– Villin; TAIR: AT4G30160.1 villin 4; Swiss-Prot: sp|O65570|VILI4_ARATH Villin-4; TrEMBL-Plants: tr|K7LWU7|K7LWU7_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0303900
Domains
27
LotjaGi4g1v0368900.1
– Protein transport protein SEC23; TAIR: AT1G05520.1 Sec23/Sec24 protein transport family protein; Swiss-Prot: sp|Q4PE39|SEC23_USTMA Protein transport protein SEC23; TrEMBL-Plants: tr|A0A1J7GI99|A0A1J7GI99_LUPAN Uncharacterized protein; Found in the gene: LotjaGi4g1v0368900
Domains
30
LotjaGi4g1v0368900.2
– Protein transport protein SEC23; TAIR: AT1G05520.1 Sec23/Sec24 protein transport family protein; Swiss-Prot: sp|Q4PE39|SEC23_USTMA Protein transport protein SEC23; TrEMBL-Plants: tr|A0A1J7GI99|A0A1J7GI99_LUPAN Uncharacterized protein; Found in the gene: LotjaGi4g1v0368900
Domains
28
LotjaGi5g1v0138400.1
– Villin; TAIR: AT2G41740.1 villin 2; Swiss-Prot: sp|O81644|VILI2_ARATH Villin-2; TrEMBL-Plants: tr|K7K9D0|K7K9D0_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0138400
Domains
16
LotjaGi5g1v0138400.2
– Villin; TAIR: AT2G41740.1 villin 2; Swiss-Prot: sp|O81644|VILI2_ARATH Villin-2; TrEMBL-Plants: tr|K7K9D0|K7K9D0_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0138400
Domains
16
LotjaGi5g1v0138400.3
– Villin; TAIR: AT2G41740.1 villin 2; Swiss-Prot: sp|O81644|VILI2_ARATH Villin-2; TrEMBL-Plants: tr|K7K9D0|K7K9D0_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0138400
Domains
16
LotjaGi5g1v0138400.4
– Villin; TAIR: AT2G41740.1 villin 2; Swiss-Prot: sp|O81644|VILI2_ARATH Villin-2; TrEMBL-Plants: tr|K7K9D0|K7K9D0_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0138400
Domains
16
LotjaGi5g1v0138400.5
– Villin; TAIR: AT2G41740.1 villin 2; Swiss-Prot: sp|O81644|VILI2_ARATH Villin-2; TrEMBL-Plants: tr|K7LIQ6|K7LIQ6_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0138400
Domains
18
LotjaGi5g1v0346900.1
– Protein transport protein Sec24-like family; TAIR: AT4G32640.1 Sec23/Sec24 protein transport family protein; Swiss-Prot: sp|Q9M081|SC24B_ARATH Protein transport protein Sec24-like At4g32640; TrEMBL-Plants: tr|A0A151TQ51|A0A151TQ51_CAJCA Protein transport protein Sec24-like family; Found in the gene: LotjaGi5g1v0346900
Domains
30
LotjaGi5g1v0346900.2
– Protein transport protein Sec24-like family; TAIR: AT4G32640.1 Sec23/Sec24 protein transport family protein; Swiss-Prot: sp|Q9M081|SC24B_ARATH Protein transport protein Sec24-like At4g32640; TrEMBL-Plants: tr|A0A151TQ51|A0A151TQ51_CAJCA Protein transport protein Sec24-like family; Found in the gene: LotjaGi5g1v0346900
Domains
30
LotjaGi5g1v0346900.3
– Protein transport protein Sec24-like family; TAIR: AT3G44340.1 hypothetical protein; Swiss-Prot: sp|Q9M291|SC24C_ARATH Protein transport protein Sec24-like CEF; TrEMBL-Plants: tr|A0A151TQ51|A0A151TQ51_CAJCA Protein transport protein Sec24-like family; Found in the gene: LotjaGi5g1v0346900
Domains
24
LotjaGi6g1v0038800.1
– Protein transport protein SEC23; TAIR: AT5G43670.1 Sec23/Sec24 protein transport family protein; Swiss-Prot: sp|Q4PE39|SEC23_USTMA Protein transport protein SEC23; TrEMBL-Plants: tr|G8A123|G8A123_MEDTR Protein transporter Sec23-like protein; Found in the gene: LotjaGi6g1v0038800
Domains
30
LotjaGi6g1v0103600.1
– Protein transport protein SEC23; TAIR: AT1G05520.1 Sec23/Sec24 protein transport family protein; Swiss-Prot: sp|Q4PE39|SEC23_USTMA Protein transport protein SEC23; TrEMBL-Plants: tr|G7JBC0|G7JBC0_MEDTR Protein transporter Sec23-like protein; Found in the gene: LotjaGi6g1v0103600
Domains
31
LotjaGi6g1v0112900.1
– Villin; TAIR: AT2G29890.1 villin-like 1; Swiss-Prot: sp|O81643|VILI1_ARATH Villin-1; TrEMBL-Plants: tr|I1N029|I1N029_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0112900
Domains
25
LotjaGi6g1v0112900.2
– Villin; TAIR: AT2G29890.1 villin-like 1; Swiss-Prot: sp|O81643|VILI1_ARATH Villin-1; TrEMBL-Plants: tr|I1N029|I1N029_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0112900
Domains
22
LotjaGi6g1v0240100.1
– Villin; TAIR: AT4G30160.1 villin 4; Swiss-Prot: sp|O65570|VILI4_ARATH Villin-4; TrEMBL-Plants: tr|A0A0L9UAV1|A0A0L9UAV1_PHAAN Uncharacterized protein; Found in the gene: LotjaGi6g1v0240100
Domains
26
LotjaGi6g1v0240100.2
– Villin; TAIR: AT4G30160.1 villin 4; Swiss-Prot: sp|O65570|VILI4_ARATH Villin-4; TrEMBL-Plants: tr|A0A0L9UAV1|A0A0L9UAV1_PHAAN Uncharacterized protein; Found in the gene: LotjaGi6g1v0240100
Domains
25
LotjaGi6g1v0240100.3
– Villin; TAIR: AT4G30160.1 villin 4; Swiss-Prot: sp|O65570|VILI4_ARATH Villin-4; TrEMBL-Plants: tr|A0A0L9UAV1|A0A0L9UAV1_PHAAN Uncharacterized protein; Found in the gene: LotjaGi6g1v0240100
Domains
25
LotjaGi6g1v0240100.4
– Villin; TAIR: AT4G30160.1 villin 4; Swiss-Prot: sp|O65570|VILI4_ARATH Villin-4; TrEMBL-Plants: tr|A0A0L9UAV1|A0A0L9UAV1_PHAAN Uncharacterized protein; Found in the gene: LotjaGi6g1v0240100
Domains
26
LotjaGi6g1v0240100.5
– Villin; TAIR: AT4G30160.1 villin 4; Swiss-Prot: sp|O65570|VILI4_ARATH Villin-4; TrEMBL-Plants: tr|A0A0L9UAV1|A0A0L9UAV1_PHAAN Uncharacterized protein; Found in the gene: LotjaGi6g1v0240100
Domains
24

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 2.13