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IPR014877

Source: InterPro

Description

IPR014877 is a Exportin-1, C-terminal.

<p>CRM1 (also known as exportin1) mediates the nuclear export of proteins bearing a leucine-rich nuclear export signal (NES). CRM1 forms a complex with the NES containing protein and the small GTPase Ran.</p> <p>This entry represents the C-terminal domain of CRM1. It forms an α helical structure formed by six helical hairpin motifs that are structurally similar to the HEAT repeat, but share little sequence similarity to the HEAT repeat [[cite:PUB00032215]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0005049
Molecular function Nuclear export signal receptor activity Combining with a nuclear export signal (NES) on a cargo to be transported, to mediate transport of a the cargo through the nuclear pore, from the nuclear lumen to the cytoplasm. The cargo can be either a RNA or a protein.
Subterm of

Associated Lotus transcripts 16

Transcript Name Description Predicted domains Domain count
Lj1g3v3716950.1
– Exportin-1 [Medicago truncatula] gi|357481145|ref|XP_003610858.1|
Domains
11
Lj1g3v5000600.1
– PREDICTED: exportin-4-like isoform X1 [Cicer arietinum] gi|502113754|ref|XP_004494748.1|
Domains
8
Lj2g3v2124900.1
– PREDICTED: exportin-1-like isoform 2 [Glycine max] gi|356538753|ref|XP_003537865.1|
Domains
8
Lj3g3v3627880.1
– PREDICTED: exportin-1-like isoform 1 [Glycine max] gi|356538463|ref|XP_003537723.1|
Domains
14
Lj3g3v3628910.1
– PREDICTED: exportin-1-like isoform 1 [Glycine max] gi|356538463|ref|XP_003537723.1|
Domains
14
LotjaGi1g1v0785100.1
– Exportin-4; TAIR: AT3G04490.2 exportin-4 protein; Swiss-Prot: sp|Q499Y0|XPO4_XENLA Exportin-4; TrEMBL-Plants: tr|K7N067|K7N067_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0785100
Domains
8
LotjaGi1g1v0785100.2
– Exportin-4; TAIR: AT3G04490.2 exportin-4 protein; Swiss-Prot: sp|Q5ZMR9|XPO4_CHICK Exportin-4; TrEMBL-Plants: tr|K7N067|K7N067_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0785100
Domains
8
LotjaGi1g1v0785100.3
– Exportin-4; TAIR: AT3G04490.2 exportin-4 protein; Swiss-Prot: sp|Q499Y0|XPO4_XENLA Exportin-4; TrEMBL-Plants: tr|K7N067|K7N067_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0785100
Domains
13
LotjaGi1g1v0785100.4
– Exportin-4; TAIR: AT3G04490.2 exportin-4 protein; Swiss-Prot: sp|Q499Y0|XPO4_XENLA Exportin-4; TrEMBL-Plants: tr|K7N067|K7N067_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0785100
Domains
13
LotjaGi2g1v0449000.1
– Exportin-1; TAIR: AT5G17020.1 exportin 1A; Swiss-Prot: sp|Q9SMV6|XPO1A_ARATH Protein EXPORTIN 1A; TrEMBL-Plants: tr|A0A0S3SEC4|A0A0S3SEC4_PHAAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0449000
Domains
24
LotjaGi2g1v0449000.3
– Exportin-1; TAIR: AT5G17020.1 exportin 1A; Swiss-Prot: sp|Q9SMV6|XPO1A_ARATH Protein EXPORTIN 1A; TrEMBL-Plants: tr|A0A0S3SEC4|A0A0S3SEC4_PHAAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0449000
Domains
24
LotjaGi2g1v0449000.4
– Exportin-1; TAIR: AT5G17020.1 exportin 1A; Swiss-Prot: sp|Q9SMV6|XPO1A_ARATH Protein EXPORTIN 1A; TrEMBL-Plants: tr|A0A0S3SEC4|A0A0S3SEC4_PHAAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0449000
Domains
24
LotjaGi2g1v0449000.6
– Exportin-1; TAIR: AT5G17020.2 exportin 1A; Swiss-Prot: sp|Q9SMV6|XPO1A_ARATH Protein EXPORTIN 1A; TrEMBL-Plants: tr|A0A0L9V7V7|A0A0L9V7V7_PHAAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0449000
Domains
24
LotjaGi2g1v0449000.7
– Exportin-1; TAIR: AT5G17020.1 exportin 1A; Swiss-Prot: sp|Q9SMV6|XPO1A_ARATH Protein EXPORTIN 1A; TrEMBL-Plants: tr|A0A0S3SEC4|A0A0S3SEC4_PHAAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0449000
Domains
24
LotjaGi3g1v0538500.1
– Exportin-1; TAIR: AT5G17020.1 exportin 1A; Swiss-Prot: sp|Q9SMV6|XPO1A_ARATH Protein EXPORTIN 1A; TrEMBL-Plants: tr|I1LII4|I1LII4_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0538500
Domains
21
LotjaGi3g1v0538500.3
– Exportin-1; TAIR: AT5G17020.1 exportin 1A; Swiss-Prot: sp|Q9SMV6|XPO1A_ARATH Protein EXPORTIN 1A; TrEMBL-Plants: tr|I1LII4|I1LII4_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0538500
Domains
24

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
TRANSMEMBRANE Phobius 1 6.25