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IPR016438 is a ATP-dependent RNA helicase SKI2-like.
<p>This family represents a group of ATP-dependent RNA helicases and their homologues, including Superkiller complex protein 2 (SKI2) and RNA helicase Mtr4 (also known as Dob1). SKI2 is a RNA helicase that forms Ski complex, which participates in many cytoplasmic pathways of the exosome in both yeast and metazoan cells, including 3'-to-5' mRNA turnover [[cite:PUB00074525], [cite:PUB00151108], [cite:PUB00151109]]. Mtr4 is a ATP-dependent 3'-5' RNA helicase involved in nuclear RNA processing and degradation [[cite:PUB00074526], [cite:PUB00074528]]. This entry also includes Arabidopsis AtMTR4 (AT1G59760) and HEN2 (AT2G06990), which target specific subsets of nuclear transcripts for degradation by the nuclear exosome [[cite:PUB00074527]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | RNA binding | Interacting selectively and non-covalently with an RNA molecule or a portion thereof. | ||
| Molecular function | RNA helicase activity | Catalysis of the reaction: NTP + H2O = NDP + phosphate, to drive the unwinding of a RNA helix. | ||
| Biological process | RNA catabolic process | The chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: superkiller viralicidic activity 2-like 2-like [Glycine max] gi|356527455|ref|XP_003532326.1| | 23 | ||
| – | PREDICTED: helicase SKI2W-like [Glycine max] gi|356569566|ref|XP_003552970.1| | 21 | ||
| – | ATP-dependent RNA helicase family protein; TAIR: AT1G59760.1 RNA helicase, ATP-dependent, SK12/DOB1 protein; Swiss-Prot: sp|Q9XIF2|MTR4_ARATH DExH-box ATP-dependent RNA helicase DExH9; TrEMBL-Plants: tr|V7AZU7|V7AZU7_PHAVU Uncharacterized protein; Found in the gene: LotjaGi1g1v0553600 | 28 | ||
| – | ATP-dependent RNA helicase family protein; TAIR: AT2G06990.1 RNA helicase, ATP-dependent, SK12/DOB1 protein; Swiss-Prot: sp|Q9ZVW2|HEN2_ARATH DExH-box ATP-dependent RNA helicase DExH10; TrEMBL-Plants: tr|I1KPQ5|I1KPQ5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0439700 | 29 | ||
| – | ATP-dependent RNA helicase family protein; TAIR: AT2G06990.1 RNA helicase, ATP-dependent, SK12/DOB1 protein; Swiss-Prot: sp|Q9ZVW2|HEN2_ARATH DExH-box ATP-dependent RNA helicase DExH10; TrEMBL-Plants: tr|I1KPQ5|I1KPQ5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0439700 | 29 | ||
| – | ATP-dependent RNA helicase family protein; TAIR: AT3G46960.2 RNA helicase, ATP-dependent, SK12/DOB1 protein; Swiss-Prot: sp|F4JAA5|SKI2_ARATH DExH-box ATP-dependent RNA helicase DExH11; TrEMBL-Plants: tr|I1N032|I1N032_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0134200 | 28 | ||
| – | ATP-dependent RNA helicase family protein; TAIR: AT3G46960.1 RNA helicase, ATP-dependent, SK12/DOB1 protein; Swiss-Prot: sp|F4JAA5|SKI2_ARATH DExH-box ATP-dependent RNA helicase DExH11; TrEMBL-Plants: tr|I1N032|I1N032_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0134200 | 28 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 14.29 |