Your browser is unable to support new features implemented in HTML5 and CSS3 to render this site as intended. Your experience may suffer from functionality degradation but the site should remain usable. We strongly recommend the latest version of Google Chrome, OS X Safari or Mozilla Firefox. As Safari is bundled with OS X, if you are unable to upgrade to a newer version of OS X, we recommend using an open source browser. Dismiss message

IPR023426

Source: InterPro

Description

IPR023426 is a Flap endonuclease 1.

<p>This entry represents an endonuclease that cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment [[cite:PUB00054247]]. It has 5'-endo-/exonuclease and 5'-pseudo-Y-endonuclease activities and cleaves the junction between single and double-stranded regions of flap DNA.</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0016788
Molecular function Hydrolase activity, acting on ester bonds Catalysis of the hydrolysis of any ester bond.
Subterm of

Associated Lotus transcripts 4

Transcript Name Description Predicted domains Domain count
Lj5g3v1533400.1
– PREDICTED: flap endonuclease 1-like isoform X3 [Cicer arietinum] gi|502117445|ref|XP_004495823.1|
Domains
19
Lj5g3v1533400.3
– PREDICTED: flap endonuclease 1-like isoform X3 [Cicer arietinum] gi|502117445|ref|XP_004495823.1|
Domains
23
LotjaGi5g1v0234800.1
– Flap endonuclease 1; TAIR: AT5G26680.2 5'-3' exonuclease family protein; Swiss-Prot: sp|C6TEX6|FEN1_SOYBN Flap endonuclease 1; TrEMBL-Plants: tr|I3SAA1|I3SAA1_LOTJA Flap endonuclease 1; Found in the gene: LotjaGi5g1v0234800
Domains
27
LotjaGi5g1v0234800.2
– Flap endonuclease 1; TAIR: AT5G26680.3 5'-3' exonuclease family protein; Swiss-Prot: sp|C6TEX6|FEN1_SOYBN Flap endonuclease 1; TrEMBL-Plants: tr|A0A072VM97|A0A072VM97_MEDTR Flap endonuclease 1; Found in the gene: LotjaGi5g1v0234800
Domains
26

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
cd09907 CDD 1 25.00