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IPR036279

Description

IPR036279 is a 5'-3' exonuclease, C-terminal domain superfamily.

<p>This entry represents the C-terminal domain of 5' to 3' exonucleases. The 5'-3' exonucleases are conserved in organisms as diverse as bacteriophage and mammals. It adopts a SAM fold consisting of 4-5 helices packed into a bundle of two orthogonally packed α-hairpins. This domain is involved in interactions with DNA and proteins. 5' to 3' exonucleases that contain this domain include:</p> <ul><li>Bacteriophage T4 RNase H, which has sequence similarity to the RAD2 family of eukaryotic proteins [[cite:PUB00011713]].</li> <li>5' to 3' exonuclease domain of DNA polymerase Taq, which is homologous to Escherichia coli DNA polymerase I (pol I) [[cite:PUB00022733]].</li> <li>Bacteriophage T5 5'-exonuclease, which are structure-specific endonucleases [[cite:PUB00011714]].</li> <li>Flap endonuclease-1 (Fen-1 nuclease), a structure specific nuclease that is an essential enzyme for eukaryotic DNA replication and repair [[cite:PUB00011712]].</li></ul>

This description is obtained from EB-eye REST.

Associated GO terms

Unable to find any GO terms for the transcript with the identifier.

Associated Lotus transcripts 10

Transcript Name Description Predicted domains Domain count
Flap endonuclease 1; TAIR: AT1G01880.1 5'-3' exonuclease family protein; Swiss-Prot: sp|Q64MA3|GENL1_ORYSJ Flap endonuclease GEN-like 1; TrEMBL-Plants: tr|A2Q3P8|A2Q3P8_MEDTR Flap endonuclease GEN-like protein; Found in the gene: LotjaGi1g1v0469700 17
Flap endonuclease 1; TAIR: AT3G28030.1 5'-3' exonuclease family protein; Swiss-Prot: sp|Q9ATY5|UVH3_ARATH DNA repair protein UVH3; TrEMBL-Plants: tr|K7K2I9|K7K2I9_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0605700 20
Flap endonuclease 1; TAIR: AT3G28030.1 5'-3' exonuclease family protein; Swiss-Prot: sp|Q9ATY5|UVH3_ARATH DNA repair protein UVH3; TrEMBL-Plants: tr|K7K2I9|K7K2I9_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0605700 26
Flap endonuclease 1; TAIR: AT3G28030.1 5'-3' exonuclease family protein; Swiss-Prot: sp|Q9ATY5|UVH3_ARATH DNA repair protein UVH3; TrEMBL-Plants: tr|K7K2I9|K7K2I9_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0605700 24
5'-3' exonuclease; TAIR: AT1G34380.2 5'-3' exonuclease family protein; Swiss-Prot: sp|O67550|EX53_AQUAE 5'-3' exonuclease; TrEMBL-Plants: tr|K7MHK5|K7MHK5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0098200 16
Flap endonuclease 1; TAIR: AT3G48900.2 single-stranded DNA endonuclease family protein; Swiss-Prot: sp|Q9M2Z3|GENL2_ARATH Flap endonuclease GEN-like 2; TrEMBL-Plants: tr|K7MIH1|K7MIH1_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0144600 24
Flap endonuclease Xni; TAIR: AT3G52050.1 5'-3' exonuclease family protein; Swiss-Prot: sp|O52225|DPO1_THEFI DNA polymerase I, thermostable; TrEMBL-Plants: tr|A0A0S3R340|A0A0S3R340_PHAAN Uncharacterized protein; Found in the gene: LotjaGi4g1v0069300 19
Flap endonuclease 1; TAIR: AT1G29630.2 5'-3' exonuclease family protein; Swiss-Prot: sp|Q60GC1|EXO1_ORYSJ Exonuclease 1; TrEMBL-Plants: tr|K7L667|K7L667_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0382400 25
Flap endonuclease 1; TAIR: AT5G26680.2 5'-3' exonuclease family protein; Swiss-Prot: sp|C6TEX6|FEN1_SOYBN Flap endonuclease 1; TrEMBL-Plants: tr|I3SAA1|I3SAA1_LOTJA Flap endonuclease 1; Found in the gene: LotjaGi5g1v0234800 27
Flap endonuclease 1; TAIR: AT5G26680.3 5'-3' exonuclease family protein; Swiss-Prot: sp|C6TEX6|FEN1_SOYBN Flap endonuclease 1; TrEMBL-Plants: tr|A0A072VM97|A0A072VM97_MEDTR Flap endonuclease 1; Found in the gene: LotjaGi5g1v0234800 26

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
cd09907 CDD 1 10.00