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IPR036097 is a Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily.
<p>This entry represents the dimerisation and phosphoacceptor domain superfamily found in some histidine kinases. Signal transducing histidine kinases are the key elements in two-component signal transduction systems, which control complex processes such as the initiation of development in microorganisms [[cite:PUB00013246]]. Examples of histidine kinases are EnvZ, which plays a central role in osmoregulation [[cite:PUB00013247]]. Histidine kinases usually have an N-terminal ligand-binding domain and a C-terminal kinase domain, but other domains may also be present. The kinase domain is responsible for the autophosphorylation of the histidine with ATP, the phosphotransfer from the kinase to an aspartate of the response regulator, and the phosphotransfer from aspartyl phosphate back to ADP or to water [[cite:PUB00020801]]. The homodimeric domain includes the site of histidine autophosphorylation and phosphate transfer reactions. The structure of the homodimeric domain comprises a closed, four-helical bundle with a left-handed twist, formed by two identical α-hairpin subunits.</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | Phosphorelay sensor kinase activity | Catalysis of the phosphorylation of a histidine residue in response to detection of an extracellular signal such as a chemical ligand or change in environment, to initiate a change in cell state or activity. The two-component sensor is a histidine kinase that autophosphorylates a histidine residue in its active site. The phosphate is then transferred to an aspartate residue in a downstream response regulator, to trigger a response. | ||
| Biological process | Signal transduction | The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | Histidine kinase; TAIR: AT5G35750.1 histidine kinase 2; Swiss-Prot: sp|Q9C5U2|AHK2_ARATH Histidine kinase 2; TrEMBL-Plants: tr|A0A023W2C6|A0A023W2C6_LOTJA Histidine kinase 2; Found in the gene: LotjaGi1g1v0008500 | 38 | ||
| – | Histidine kinase; TAIR: AT2G47430.1 Signal transduction histidine kinase; Swiss-Prot: sp|O22267|CKI1_ARATH Histidine kinase CKI1; TrEMBL-Plants: tr|V7BJF4|V7BJF4_PHAVU Uncharacterized protein; Found in the gene: LotjaGi1g1v0060100 | 33 | ||
| – | Histidine kinase; TAIR: AT5G10720.1 histidine kinase 5; Swiss-Prot: sp|A3BE68|OHK1_ORYSJ Probable histidine kinase 1; TrEMBL-Plants: tr|V7AWB7|V7AWB7_PHAVU Uncharacterized protein; Found in the gene: LotjaGi1g1v0373800 | 30 | ||
| – | Ethylene receptor; TAIR: AT2G40940.1 ethylene response sensor 1; Swiss-Prot: sp|Q38846|ERS1_ARATH Ethylene response sensor 1; TrEMBL-Plants: tr|A0A151S8B3|A0A151S8B3_CAJCA Ethylene receptor; Found in the gene: LotjaGi1g1v0762500 | 30 | ||
| – | Ethylene receptor; TAIR: AT2G40940.1 ethylene response sensor 1; Swiss-Prot: sp|Q38846|ERS1_ARATH Ethylene response sensor 1; TrEMBL-Plants: tr|A0A151S8B3|A0A151S8B3_CAJCA Ethylene receptor; Found in the gene: LotjaGi1g1v0762500 | 30 | ||
| – | Ethylene receptor; TAIR: AT3G04580.1 Signal transduction histidine kinase, hybrid-type, ethylene sensor; Swiss-Prot: sp|Q9ZTP3|EIN4_ARATH Protein EIN4; TrEMBL-Plants: tr|G7L2X0|G7L2X0_MEDTR Ethylene receptor; Found in the gene: LotjaGi1g1v0786100 | 40 | ||
| – | Ethylene receptor; TAIR: AT3G04580.1 Signal transduction histidine kinase, hybrid-type, ethylene sensor; Swiss-Prot: sp|Q9ZTP3|EIN4_ARATH Protein EIN4; TrEMBL-Plants: tr|G7L2X0|G7L2X0_MEDTR Ethylene receptor; Found in the gene: LotjaGi1g1v0786100 | 40 | ||
| – | Ethylene receptor; TAIR: AT3G04580.1 Signal transduction histidine kinase, hybrid-type, ethylene sensor; Swiss-Prot: sp|Q9ZTP3|EIN4_ARATH Protein EIN4; TrEMBL-Plants: tr|G7L2X0|G7L2X0_MEDTR Ethylene receptor; Found in the gene: LotjaGi1g1v0786100 | 36 | ||
| – | Histidine kinase; TAIR: AT2G01830.2 CHASE domain containing histidine kinase protein; Swiss-Prot: sp|Q9C5U0|AHK4_ARATH Histidine kinase 4; TrEMBL-Plants: tr|A3QVR9|A3QVR9_LOTJA Histidine kinase 1A; Found in the gene: LotjaGi2g1v0003400 | 36 | ||
| – | Histidine kinase; TAIR: AT2G01830.1 CHASE domain containing histidine kinase protein; Swiss-Prot: sp|Q9C5U0|AHK4_ARATH Histidine kinase 4; TrEMBL-Plants: tr|A3QVR9|A3QVR9_LOTJA Histidine kinase 1A; Found in the gene: LotjaGi2g1v0003400 | 35 | ||
| – | Histidine kinase; TAIR: AT2G01830.2 CHASE domain containing histidine kinase protein; Swiss-Prot: sp|Q9C5U0|AHK4_ARATH Histidine kinase 4; TrEMBL-Plants: tr|A3QVR9|A3QVR9_LOTJA Histidine kinase 1A; Found in the gene: LotjaGi2g1v0003400 | 35 | ||
| – | Histidine kinase; TAIR: AT2G01830.2 CHASE domain containing histidine kinase protein; Swiss-Prot: sp|Q9C5U0|AHK4_ARATH Histidine kinase 4; TrEMBL-Plants: tr|A3QVR9|A3QVR9_LOTJA Histidine kinase 1A; Found in the gene: LotjaGi2g1v0003400 | 36 | ||
| – | Histidine kinase; TAIR: AT2G01830.2 CHASE domain containing histidine kinase protein; Swiss-Prot: sp|Q9C5U0|AHK4_ARATH Histidine kinase 4; TrEMBL-Plants: tr|A3QVR9|A3QVR9_LOTJA Histidine kinase 1A; Found in the gene: LotjaGi2g1v0003400 | 35 | ||
| – | Histidine kinase; TAIR: AT2G01830.1 CHASE domain containing histidine kinase protein; Swiss-Prot: sp|Q9C5U0|AHK4_ARATH Histidine kinase 4; TrEMBL-Plants: tr|A3QVR9|A3QVR9_LOTJA Histidine kinase 1A; Found in the gene: LotjaGi2g1v0003400 | 35 | ||
| – | Histidine kinase; TAIR: AT2G01830.1 CHASE domain containing histidine kinase protein; Swiss-Prot: sp|Q9C5U0|AHK4_ARATH Histidine kinase 4; TrEMBL-Plants: tr|A3QVR9|A3QVR9_LOTJA Histidine kinase 1A; Found in the gene: LotjaGi2g1v0003400 | 35 | ||
| – | Histidine kinase; TAIR: AT2G01830.2 CHASE domain containing histidine kinase protein; Swiss-Prot: sp|Q9C5U0|AHK4_ARATH Histidine kinase 4; TrEMBL-Plants: tr|A3QVR9|A3QVR9_LOTJA Histidine kinase 1A; Found in the gene: LotjaGi2g1v0003400 | 36 | ||
| – | Histidine kinase; TAIR: AT2G17820.1 histidine kinase 1; Swiss-Prot: sp|Q9SXL4|AHK1_ARATH Histidine kinase 1; TrEMBL-Plants: tr|A0A0B2RSC6|A0A0B2RSC6_GLYSO Histidine kinase 1; Found in the gene: LotjaGi2g1v0379900 | 33 | ||
| – | Histidine kinase; TAIR: AT2G17820.1 histidine kinase 1; Swiss-Prot: sp|Q9SXL4|AHK1_ARATH Histidine kinase 1; TrEMBL-Plants: tr|A0A0B2RSC6|A0A0B2RSC6_GLYSO Histidine kinase 1; Found in the gene: LotjaGi2g1v0379900 | 33 | ||
| – | Ethylene receptor; TAIR: AT1G66340.1 Signal transduction histidine kinase, hybrid-type, ethylene sensor; Swiss-Prot: sp|O81122|ETR1_MALDO Ethylene receptor; TrEMBL-Plants: tr|I1LVH5|I1LVH5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0054100 | 40 | ||
| – | Ethylene receptor; TAIR: AT1G66340.1 Signal transduction histidine kinase, hybrid-type, ethylene sensor; Swiss-Prot: sp|O81122|ETR1_MALDO Ethylene receptor; TrEMBL-Plants: tr|I1LVH5|I1LVH5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0054100 | 40 | ||
| – | Ethylene receptor; TAIR: AT1G66340.1 Signal transduction histidine kinase, hybrid-type, ethylene sensor; Swiss-Prot: sp|Q9M7M1|ETR1_PRUPE Ethylene receptor; TrEMBL-Plants: tr|K7LB32|K7LB32_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0054100 | 37 | ||
| – | Ethylene receptor; TAIR: AT1G66340.1 Signal transduction histidine kinase, hybrid-type, ethylene sensor; Swiss-Prot: sp|O81122|ETR1_MALDO Ethylene receptor; TrEMBL-Plants: tr|A0A1J7HIG6|A0A1J7HIG6_LUPAN Uncharacterized protein; Found in the gene: LotjaGi3g1v0054100 | 40 | ||
| – | Histidine kinase; TAIR: AT2G17820.1 histidine kinase 1; Swiss-Prot: sp|Q9SXL4|AHK1_ARATH Histidine kinase 1; TrEMBL-Plants: tr|G7JXI9|G7JXI9_MEDTR Osmosensor histidine kinase; Found in the gene: LotjaGi3g1v0084800_LC | 9 | ||
| – | Histidine kinase; TAIR: AT2G17820.1 histidine kinase 1; Swiss-Prot: sp|Q9SXL4|AHK1_ARATH Histidine kinase 1; TrEMBL-Plants: tr|K7MGY5|K7MGY5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0129800 | 33 | ||
| – | Histidine kinase; TAIR: AT1G27320.1 histidine kinase 3; Swiss-Prot: sp|Q9C5U1|AHK3_ARATH Histidine kinase 3; TrEMBL-Plants: tr|A0A023W3N9|A0A023W3N9_LOTJA Histidine kinase 3 variant 1; Found in the gene: LotjaGi4g1v0366900 | 39 | ||
| – | Histidine kinase; TAIR: AT1G27320.1 histidine kinase 3; Swiss-Prot: sp|Q9C5U1|AHK3_ARATH Histidine kinase 3; TrEMBL-Plants: tr|A0A023W2K9|A0A023W2K9_LOTJA Histidine kinase 3 variant 2; Found in the gene: LotjaGi4g1v0366900 | 39 | ||
| – | Histidine kinase; TAIR: AT1G27320.1 histidine kinase 3; Swiss-Prot: sp|Q9C5U1|AHK3_ARATH Histidine kinase 3; TrEMBL-Plants: tr|A0A023W2K9|A0A023W2K9_LOTJA Histidine kinase 3 variant 2; Found in the gene: LotjaGi4g1v0366900 | 40 | ||
| – | Histidine kinase; TAIR: AT2G01830.1 CHASE domain containing histidine kinase protein; Swiss-Prot: sp|Q9C5U0|AHK4_ARATH Histidine kinase 4; TrEMBL-Plants: tr|A0PEY0|A0PEY0_LOTJA Cytokinin receptor 1; Found in the gene: LotjaGi4g1v0459800 | 37 | ||
| – | Histidine kinase; TAIR: AT2G01830.1 CHASE domain containing histidine kinase protein; Swiss-Prot: sp|Q9C5U0|AHK4_ARATH Histidine kinase 4; TrEMBL-Plants: tr|A0PEY0|A0PEY0_LOTJA Cytokinin receptor 1; Found in the gene: LotjaGi4g1v0459800 | 37 | ||
| – | Histidine kinase; TAIR: AT2G01830.1 CHASE domain containing histidine kinase protein; Swiss-Prot: sp|Q9C5U0|AHK4_ARATH Histidine kinase 4; TrEMBL-Plants: tr|A0PEY0|A0PEY0_LOTJA Cytokinin receptor 1; Found in the gene: LotjaGi4g1v0459800 | 37 | ||
| – | Histidine kinase; TAIR: AT5G10720.1 histidine kinase 5; Swiss-Prot: sp|Q3S4A7|AHK5_ARATH Histidine kinase 5; TrEMBL-Plants: tr|A0A0L9V1D7|A0A0L9V1D7_PHAAN Uncharacterized protein; Found in the gene: LotjaGi5g1v0050100 | 30 | ||
| – | Histidine kinase; TAIR: AT5G10720.1 histidine kinase 5; Swiss-Prot: sp|Q3S4A7|AHK5_ARATH Histidine kinase 5; TrEMBL-Plants: tr|A0A0L9V1D7|A0A0L9V1D7_PHAAN Uncharacterized protein; Found in the gene: LotjaGi5g1v0050100 | 30 | ||
| – | Ethylene receptor; TAIR: AT3G23150.1 Signal transduction histidine kinase, hybrid-type, ethylene sensor; Swiss-Prot: sp|Q0WPQ2|ETR2_ARATH Ethylene receptor 2; TrEMBL-Plants: tr|A0A1J7GKM4|A0A1J7GKM4_LUPAN Uncharacterized protein; Found in the gene: LotjaGi5g1v0182400 | 38 | ||
| – | Ethylene receptor; TAIR: AT3G23150.1 Signal transduction histidine kinase, hybrid-type, ethylene sensor; Swiss-Prot: sp|Q0WPQ2|ETR2_ARATH Ethylene receptor 2; TrEMBL-Plants: tr|A0A1J7GKM4|A0A1J7GKM4_LUPAN Uncharacterized protein; Found in the gene: LotjaGi5g1v0182400 | 38 | ||
| – | Ethylene receptor like-protein; TAIR: AT3G04580.1 Signal transduction histidine kinase, hybrid-type, ethylene sensor; Swiss-Prot: sp|Q9ZTP3|EIN4_ARATH Protein EIN4; TrEMBL-Plants: tr|A0A0B2Q4A5|A0A0B2Q4A5_GLYSO Protein EIN4; Found in the gene: LotjaGi5g1v0206300 | 40 | ||
| – | Histidine kinase 1; TAIR: AT2G47430.1 Signal transduction histidine kinase; Swiss-Prot: sp|O22267|CKI1_ARATH Histidine kinase CKI1; TrEMBL-Plants: tr|A0A1J7HYZ6|A0A1J7HYZ6_LUPAN Uncharacterized protein; Found in the gene: LotjaGi5g1v0245400_LC | 9 | ||
| – | Phytochrome; TAIR: AT2G18790.1 phytochrome B; Swiss-Prot: sp|P42499|PHYB_SOYBN Phytochrome B; TrEMBL-Plants: tr|A1IIA2|A1IIA2_LOTJA Phytochrome; Found in the gene: LotjaGi6g1v0258900 | 49 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 2.70 |