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IPR039309 is a Biopterin transporter family.
<p>Members of this family are transmembrane proteins. Several are Leishmania putative proteins that are thought to be pteridine transporters. One such protein [swissprot:Q25272], previously termed (and is still annotated as) ORFG, was shown to encode a biopterin transport protein using null mutants [[cite:PUB00007508]], thus being subsequently renamed BT1. The significant similarity of ORFG/BT1 to Trypanosoma brucei ESAG10 (a putative transmembrane protein and another member of this family) was previously noted [[cite:PUB00007509]]. This family also contains folate-biopterin transporters (FBTs) from blue-green algae and plants, including Slr0642 protein from Synechocystis and its plastidial orthologue At2g32040 from Arabidopsis [[cite:PUB00071846]]. Both Slr0642 protein and At2g32040 mediate folate monoglutamate transport involved in tetrahydrofolate biosynthesis. However, this entry also includes seven other Arabidopsis FBT proteins that lack conserved critical residues and may not have folate or pterin transport activity [[cite:PUB00071846]]. In addition, it also contains two predicted prokaryotic proteins (from the cyanobacteria Synechocystis and Synechococcus).</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | Major facilitator superfamily protein; TAIR: AT5G25050.1 Major facilitator superfamily protein; Swiss-Prot: sp|Q5FV41|FBT2_ARATH Probable folate-biopterin transporter 2; TrEMBL-Plants: tr|A0A1J7HQ91|A0A1J7HQ91_LUPAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0376000 | 12 | ||
| – | FBT8; TAIR: AT2G33280.1 Major facilitator superfamily protein; Swiss-Prot: sp|O22780|FBT9_ARATH Probable folate-biopterin transporter 9, chloroplastic; TrEMBL-Plants: tr|G7IVP1|G7IVP1_MEDTR Folate/biopterin transporter; Found in the gene: LotjaGi3g1v0327100 | 15 | ||
| – | Major facilitator superfamily protein; TAIR: AT5G10820.1 Major facilitator superfamily protein; Swiss-Prot: sp|Q9LEV7|FBT6_ARATH Probable folate-biopterin transporter 6; TrEMBL-Plants: tr|K7MND7|K7MND7_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0053400 | 14 | ||
| – | Major facilitator superfamily protein; TAIR: AT5G10820.1 Major facilitator superfamily protein; Swiss-Prot: sp|Q9LEV7|FBT6_ARATH Probable folate-biopterin transporter 6; TrEMBL-Plants: tr|K7MND7|K7MND7_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0053400 | 11 | ||
| – | Major facilitator superfamily protein; TAIR: AT5G25050.1 Major facilitator superfamily protein; Swiss-Prot: sp|Q5FV41|FBT2_ARATH Probable folate-biopterin transporter 2; TrEMBL-Plants: tr|I3S4W1|I3S4W1_LOTJA Uncharacterized protein; Found in the gene: LotjaGi5g1v0054100 | 14 | ||
| – | Folate/biopterin transporter; TAIR: AT2G32040.1 Major facilitator superfamily protein; Swiss-Prot: sp|Q9SKZ5|FBT1_ARATH Folate-biopterin transporter 1, chloroplastic; TrEMBL-Plants: tr|A0A0R0ELM0|A0A0R0ELM0_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0312700 | 15 | ||
| – | Folate/biopterin transporter; TAIR: AT2G32040.1 Major facilitator superfamily protein; Swiss-Prot: sp|Q9SKZ5|FBT1_ARATH Folate-biopterin transporter 1, chloroplastic; TrEMBL-Plants: tr|A0A0R0ELM0|A0A0R0ELM0_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0312700 | 14 | ||
| – | Folate/biopterin transporter; TAIR: AT2G32040.1 Major facilitator superfamily protein; Swiss-Prot: sp|Q9SKZ5|FBT1_ARATH Folate-biopterin transporter 1, chloroplastic; TrEMBL-Plants: tr|N1NKH4|N1NKH4_ARAHY Putative transmembrane BT1 family protein; Found in the gene: LotjaGi5g1v0312700 | 14 | ||
| – | Major facilitator superfamily protein; TAIR: AT5G54860.1 Major facilitator superfamily protein; Swiss-Prot: sp|Q8RWQ5|FBT4_ARATH Probable folate-biopterin transporter 4; TrEMBL-Plants: tr|I1KY57|I1KY57_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0166200 | 14 | ||
| – | Folate/biopterin transporter; TAIR: AT5G54860.1 Major facilitator superfamily protein; Swiss-Prot: sp|Q8RWQ5|FBT4_ARATH Probable folate-biopterin transporter 4; TrEMBL-Plants: tr|I1KY57|I1KY57_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0166200 | 12 | ||
| – | Major facilitator superfamily protein; TAIR: AT1G64890.1 Major facilitator superfamily protein; Swiss-Prot: sp|Q9XIQ7|FBT7_ARATH Probable folate-biopterin transporter 7; TrEMBL-Plants: tr|I3SSK5|I3SSK5_LOTJA Uncharacterized protein; Found in the gene: LotjaGi6g1v0266000 | 14 | ||
| – | Folate-biopterin transporter; TAIR: AT1G64890.1 Major facilitator superfamily protein; Swiss-Prot: sp|Q9XIQ7|FBT7_ARATH Probable folate-biopterin transporter 7; TrEMBL-Plants: tr|I3SSK5|I3SSK5_LOTJA Uncharacterized protein; Found in the gene: LotjaGi6g1v0266000 | 12 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| cd17484 | CDD | 1 | 8.33 |