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Field | Value |
---|---|
Namespace | Biological process |
Short description | Microtubule nucleation |
Full defintion | The process in which tubulin alpha-beta heterodimers begin aggregation to form an oligomeric tubulin structure (a microtubule seed). Microtubule nucleation is the initiating step in the formation of a microtubule in the absence of any existing microtubules ('de novo' microtubule formation). |
Subterm of |
The relationship of GO:0007020 with other GO terms.
Relationship type | GO terms |
---|---|
Is a | |
Regulates | n.a. |
Part of | |
Positively regulates | n.a. |
Negatively regulates | n.a. |
A force layout showing the ancestor tree for GO:0007020, and its immediate children. If you wish to explore the tree dynamically, please use the GO Explorer.
This table contains additional metadata associated with the GO entry's definition field.
Field | Value |
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GOC | go_curators |
ISBN | , · pages |
PMID | Microtubule nucleation. Curr Opin Cell Biol. 2003 Feb; 15 (1): 111–7.PMID: 12517712 Microtubule nucleation is the process in which several tubulin molecules interact to form a microtubule seed. Microtubule nucleation occurs spontaneously in purified tubulin solutions, and molecular intermediates between tubulin dimers and microtubules have been identified. Microtubule nucleation is enhanced in tubulin solutions by the addition of gamma-tubulin or various gamma-tubulin complexes. In vivo, microtubule assembly is usually seeded by gamma-tubulin ring complexes. Recent studies suggest, however, that microtubule nucleation can occur in the absence of gamma-tubulin, and that gamma-tubulin may have other cell functions apart from being a major component of the gamma-tubulin ring complex. |
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
Transcript | Name | Description | GO terms | GO count |
---|---|---|---|---|
– | Tubulin gamma-1 chain [Arabidopsis thaliana] gi|15233174|ref|NP_191724.1| | 3 | ||
– | Spc97 / Spc98 family of spindle pole body (SBP) component [Arabidopsis thaliana] gi|18412725|ref|NP_565234.1| | 5 | ||
– | Spc97 / Spc98 family of spindle pole body (SBP) component [Arabidopsis thaliana] gi|18412725|ref|NP_565234.1| | 5 | ||
– | PREDICTED: tubulin gamma-1 chain-like isoform X1 [Cicer arietinum] gi|502113903|ref|XP_004494797.1| | 3 | ||
– | PREDICTED: gamma-tubulin complex component 2-like [Glycine max] gi|356560679|ref|XP_003548617.1| | 5 | ||
– | Gamma-tubulin complex component [Medicago truncatula] gi|358343837|ref|XP_003636002.1| | 5 | ||
– | Gamma-tubulin complex component [Medicago truncatula] gi|358343837|ref|XP_003636002.1| | 5 | ||
– | Gamma-tubulin complex component [Medicago truncatula] gi|358343837|ref|XP_003636002.1| | 5 | ||
– | Gamma-tubulin complex component [Medicago truncatula] gi|358343837|ref|XP_003636002.1| | 5 | ||
– | Spc97 / Spc98 family of spindle pole body component isoform 1 [Theobroma cacao] gi|508727515|gb|EOY19412.1| | 5 | ||
– | Spc97 / Spc98 family of spindle pole body component isoform 1 [Theobroma cacao] gi|508727515|gb|EOY19412.1| | 5 | ||
– | PREDICTED: tubulin gamma-1 chain-like isoform X1 [Cicer arietinum] gi|502113903|ref|XP_004494797.1| | 3 | ||
– | Tubulin gamma-1 chain protein [Medicago truncatula] gi|357512519|ref|XP_003626548.1| | 3 | ||
– | Gamma-tubulin isoform 3 [Theobroma cacao] gi|508703887|gb|EOX95783.1| | 3 | ||
– | PREDICTED: gamma-tubulin complex component 3 homolog isoform X1 [Cicer arietinum] gi|502109270|ref|XP_004493606.1| | 5 | ||
– | PREDICTED: gamma-tubulin complex component 3 homolog isoform X1 [Cicer arietinum] gi|502109270|ref|XP_004493606.1| | 5 | ||
– | Gamma-tubulin [Vigna angularis] gi|187761602|dbj|BAG31940.1| | 3 | ||
– | Spc97 / Spc98 family of spindle pole body (SBP) component [Arabidopsis thaliana] gi|18412725|ref|NP_565234.1| | 5 | ||
– | PREDICTED: gamma-tubulin complex component 4 homolog [Glycine max] gi|356500339|ref|XP_003518990.1| | 5 | ||
– | PREDICTED: gamma-tubulin complex component 4 homolog [Glycine max] gi|356535143|ref|XP_003536108.1| | 5 | ||
– | PREDICTED: gamma-tubulin complex component 4 homolog [Cicer arietinum] gi|502117784|ref|XP_004495944.1| | 5 | ||
– | PREDICTED: gamma-tubulin complex component 4 homolog [Glycine max] gi|356500339|ref|XP_003518990.1| | 5 | ||
– | Spc97 / Spc98 family of spindle pole body (SBP) component [Arabidopsis thaliana] gi|18412725|ref|NP_565234.1| | 5 | ||
– | Tubulin beta chain; TAIR: AT3G61650.1 gamma-tubulin; Swiss-Prot: sp|P38557|TBG1_ARATH Tubulin gamma-1 chain; TrEMBL-Plants: tr|G7L416|G7L416_MEDTR Tubulin gamma chain; Found in the gene: LotjaGi1g1v0042300 | 3 | ||
– | Tubulin beta chain; TAIR: AT3G61650.1 gamma-tubulin; Swiss-Prot: sp|P38557|TBG1_ARATH Tubulin gamma-1 chain; TrEMBL-Plants: tr|G7L416|G7L416_MEDTR Tubulin gamma chain; Found in the gene: LotjaGi1g1v0042300 | 3 | ||
– | Tubulin beta chain; TAIR: AT5G05620.1 gamma-tubulin complex protein 2; Swiss-Prot: sp|Q41808|TBG2_MAIZE Tubulin gamma-2 chain; TrEMBL-Plants: tr|B9FMK1|B9FMK1_ORYSJ Dihydrolipoyl dehydrogenase; Found in the gene: LotjaGi1g1v0084400_LC | 3 | ||
– | Tubulin beta chain; TAIR: AT5G05620.1 gamma-tubulin complex protein 2; Swiss-Prot: sp|Q41808|TBG2_MAIZE Tubulin gamma-2 chain; TrEMBL-Plants: tr|B9FMK1|B9FMK1_ORYSJ Dihydrolipoyl dehydrogenase; Found in the gene: LotjaGi1g1v0084400_LC | 3 | ||
– | Tubulin beta chain; TAIR: AT5G05620.1 gamma-tubulin complex protein 2; Swiss-Prot: sp|Q41808|TBG2_MAIZE Tubulin gamma-2 chain; TrEMBL-Plants: tr|B9FMK1|B9FMK1_ORYSJ Dihydrolipoyl dehydrogenase; Found in the gene: LotjaGi1g1v0084400_LC | 3 | ||
– | Tubulin beta chain; TAIR: AT5G05620.1 gamma-tubulin complex protein 2; Swiss-Prot: sp|Q41808|TBG2_MAIZE Tubulin gamma-2 chain; TrEMBL-Plants: tr|B9FMK1|B9FMK1_ORYSJ Dihydrolipoyl dehydrogenase; Found in the gene: LotjaGi1g1v0084400_LC | 3 | ||
– | Tubulin beta chain; TAIR: AT5G05620.1 gamma-tubulin complex protein 2; Swiss-Prot: sp|Q41808|TBG2_MAIZE Tubulin gamma-2 chain; TrEMBL-Plants: tr|B9FMK1|B9FMK1_ORYSJ Dihydrolipoyl dehydrogenase; Found in the gene: LotjaGi1g1v0084400_LC | 3 | ||
– | Tubulin beta chain; TAIR: AT5G05620.1 gamma-tubulin complex protein 2; Swiss-Prot: sp|Q41808|TBG2_MAIZE Tubulin gamma-2 chain; TrEMBL-Plants: tr|B9FMK1|B9FMK1_ORYSJ Dihydrolipoyl dehydrogenase; Found in the gene: LotjaGi1g1v0084400_LC | 3 | ||
– | Tubulin beta chain; TAIR: AT5G05620.1 gamma-tubulin complex protein 2; Swiss-Prot: sp|Q41808|TBG2_MAIZE Tubulin gamma-2 chain; TrEMBL-Plants: tr|B9FMK1|B9FMK1_ORYSJ Dihydrolipoyl dehydrogenase; Found in the gene: LotjaGi1g1v0084400_LC | 3 | ||
– | Tubulin beta chain; TAIR: AT5G05620.1 gamma-tubulin complex protein 2; Swiss-Prot: sp|Q41808|TBG2_MAIZE Tubulin gamma-2 chain; TrEMBL-Plants: tr|B9FMK1|B9FMK1_ORYSJ Dihydrolipoyl dehydrogenase; Found in the gene: LotjaGi1g1v0084400_LC | 3 | ||
– | Tubulin beta chain; TAIR: AT5G05620.1 gamma-tubulin complex protein 2; Swiss-Prot: sp|Q41808|TBG2_MAIZE Tubulin gamma-2 chain; TrEMBL-Plants: tr|B9FMK1|B9FMK1_ORYSJ Dihydrolipoyl dehydrogenase; Found in the gene: LotjaGi1g1v0084400_LC | 3 | ||
– | Tubulin beta chain; TAIR: AT5G05620.1 gamma-tubulin complex protein 2; Swiss-Prot: sp|Q41808|TBG2_MAIZE Tubulin gamma-2 chain; TrEMBL-Plants: tr|B9FMK1|B9FMK1_ORYSJ Dihydrolipoyl dehydrogenase; Found in the gene: LotjaGi1g1v0084400_LC | 3 | ||
– | Gamma-tubulin complex component; TAIR: AT5G06680.1 spindle pole body component 98; Swiss-Prot: sp|Q9FG37|GACP3_ARATH Gamma-tubulin complex component 3; TrEMBL-Plants: tr|V7CYH3|V7CYH3_PHAVU Gamma-tubulin complex component; Found in the gene: LotjaGi1g1v0278900 | 5 | ||
– | Gamma-tubulin complex component; TAIR: AT5G06680.1 spindle pole body component 98; Swiss-Prot: sp|Q9FG37|GACP3_ARATH Gamma-tubulin complex component 3; TrEMBL-Plants: tr|V7CYH3|V7CYH3_PHAVU Gamma-tubulin complex component; Found in the gene: LotjaGi1g1v0278900 | 5 | ||
– | Gamma-tubulin complex component; TAIR: AT5G17410.1 Spc97 / Spc98 family of spindle pole body (SBP) component; Swiss-Prot: sp|Q9C5H9|GACP2_ARATH Gamma-tubulin complex component 2; TrEMBL-Plants: tr|A0A0R0FN05|A0A0R0FN05_SOYBN Gamma-tubulin complex component; Found in the gene: LotjaGi1g1v0290100 | 5 | ||
– | Gamma-tubulin complex component; TAIR: AT5G17410.2 Spc97 / Spc98 family of spindle pole body (SBP) component; Swiss-Prot: sp|Q9C5H9|GACP2_ARATH Gamma-tubulin complex component 2; TrEMBL-Plants: tr|A0A0R0FN05|A0A0R0FN05_SOYBN Gamma-tubulin complex component; Found in the gene: LotjaGi1g1v0290100 | 5 | ||
– | Gamma-tubulin complex component; TAIR: AT5G17410.1 Spc97 / Spc98 family of spindle pole body (SBP) component; Swiss-Prot: sp|Q9C5H9|GACP2_ARATH Gamma-tubulin complex component 2; TrEMBL-Plants: tr|A0A0R0FN05|A0A0R0FN05_SOYBN Gamma-tubulin complex component; Found in the gene: LotjaGi1g1v0290100 | 5 | ||
– | Gamma-tubulin complex component; TAIR: AT5G17410.2 Spc97 / Spc98 family of spindle pole body (SBP) component; Swiss-Prot: sp|Q9C5H9|GACP2_ARATH Gamma-tubulin complex component 2; TrEMBL-Plants: tr|A0A0R0FN05|A0A0R0FN05_SOYBN Gamma-tubulin complex component; Found in the gene: LotjaGi1g1v0290100 | 5 | ||
– | Gamma-tubulin complex component; TAIR: AT1G80260.1 Spc97 / Spc98 family of spindle pole body (SBP) component; Swiss-Prot: sp|Q8BKN5|GCP5_MOUSE Gamma-tubulin complex component 5; TrEMBL-Plants: tr|I1K7W7|I1K7W7_SOYBN Gamma-tubulin complex component; Found in the gene: LotjaGi1g1v0351500 | 5 | ||
– | Tubulin beta chain; TAIR: AT3G61650.1 gamma-tubulin; Swiss-Prot: sp|P38557|TBG1_ARATH Tubulin gamma-1 chain; TrEMBL-Plants: tr|G7L416|G7L416_MEDTR Tubulin gamma chain; Found in the gene: LotjaGi1g1v0545200 | 3 | ||
– | Tubulin beta chain; TAIR: AT3G61650.1 gamma-tubulin; Swiss-Prot: sp|P38557|TBG1_ARATH Tubulin gamma-1 chain; TrEMBL-Plants: tr|G7L416|G7L416_MEDTR Tubulin gamma chain; Found in the gene: LotjaGi1g1v0545200 | 3 | ||
– | Gamma-tubulin complex component; TAIR: AT3G43610.1 Spc97 / Spc98 family of spindle pole body (SBP) component; Swiss-Prot: sp|G5E8P0|GCP6_MOUSE Gamma-tubulin complex component 6; TrEMBL-Plants: tr|K7K5M8|K7K5M8_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0461500 | 5 | ||
– | Gamma-tubulin complex component; TAIR: AT3G43610.1 Spc97 / Spc98 family of spindle pole body (SBP) component; Swiss-Prot: sp|G5E8P0|GCP6_MOUSE Gamma-tubulin complex component 6; TrEMBL-Plants: tr|A0A0R0LJU5|A0A0R0LJU5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0461500 | 5 | ||
– | Gamma-tubulin complex component; TAIR: AT3G53760.1 GAMMA-TUBULIN COMPLEX PROTEIN 4; Swiss-Prot: sp|Q9SC88|GCP4_MEDTR Gamma-tubulin complex component 4 homolog; TrEMBL-Plants: tr|A0A151U4M2|A0A151U4M2_CAJCA Gamma-tubulin complex component; Found in the gene: LotjaGi5g1v0250000 | 5 | ||
– | Gamma-tubulin complex component; TAIR: AT3G53760.1 GAMMA-TUBULIN COMPLEX PROTEIN 4; Swiss-Prot: sp|Q9M350|GACP4_ARATH Gamma-tubulin complex component 4; TrEMBL-Plants: tr|A0A151U4M2|A0A151U4M2_CAJCA Gamma-tubulin complex component; Found in the gene: LotjaGi5g1v0250000 | 5 |
A list of co-occurring GO terms within the L. japonicus gene space:
GO term | Namespace | Name | Observations | Saturation (%) |
---|---|---|---|---|
Molecular function | Gamma-tubulin binding | 1 | 2.08 |