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IPR001000

Source: InterPro

Description

IPR001000 is a Glycoside hydrolase family 10 domain.

<p>O-Glycosyl hydrolases ([ec:3.2.1.]) are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families [[cite:PUB00004870], [cite:PUB00005266]]. This classification is available on the CAZy (CArbohydrate-Active EnZymes) website.</p> <p>Glycoside hydrolase family 10 [cazy:GH10] comprises enzymes with a number of known activities; xylanase ([ec:3.2.1.8]); endo-1,3-beta-xylanase ([ec:3.2.1.32]); cellobiohydrolase ([ec:3.2.1.91]). These enzymes were formerly known as cellulase family F.</p> <p>The microbial degradation of cellulose and xylans requires several types of enzymes such as endoglucanases ([ec:3.2.1.4]), cellobiohydrolases ([ec:3.2.1.91]) (exoglucanases), or xylanases ([ec:3.2.1.8]) [[cite:PUB00000117], [cite:PUB00003608]]. Fungi and bacteria produces a spectrum of cellulolytic enzymes (cellulases) and xylanases which, on the basis of sequence similarities, can be classified into families. One of these families is known as the cellulase family F [[cite:PUB00001778]] or as the glycosyl hydrolases family 10 [[cite:PUB00000503]].</p> <p>The overall structure of the GH10 domain corresponds to an eightfold α/β-barrel (TIM-barrel) with a typical deep groove in the centre, allowing an 'endo' type of action on the large polysaccharide backbone [[cite:PUB00048906]], [[cite:PUB00067124]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0004553
Molecular function Hydrolase activity, hydrolyzing O-glycosyl compounds Catalysis of the hydrolysis of any O-glycosyl bond.
Subterm of
GO:0005975
Biological process Carbohydrate metabolic process The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. Includes the formation of carbohydrate derivatives by the addition of a carbohydrate residue to another molecule.
Subterm of

Associated Lotus transcripts 24

Transcript Name Description Predicted domains Domain count
Lj0g3v0167789.1
– Endo-1,4-beta-xylanase C [Medicago truncatula] gi|357503165|ref|XP_003621871.1|
Domains
23
Lj0g3v0316669.1
– PREDICTED: endo-1,4-beta-xylanase A-like [Glycine max] gi|356554054|ref|XP_003545364.1|
Domains
17
Lj0g3v0316669.2
– PREDICTED: endo-1,4-beta-xylanase A-like [Glycine max] gi|356554054|ref|XP_003545364.1|
Domains
16
Lj1g3v1784210.1
– PREDICTED: exoglucanase XynX-like isoform X1 [Cicer arietinum] gi|502132694|ref|XP_004501484.1|
Domains
18
Lj1g3v1784210.2
– PREDICTED: exoglucanase XynX-like isoform X1 [Cicer arietinum] gi|502132694|ref|XP_004501484.1|
Domains
18
Lj1g3v3343780.1
– PREDICTED: exoglucanase xynX-like [Glycine max] gi|356509525|ref|XP_003523498.1|
Domains
20
Lj3g3v3500160.1
– Endo-1,4-beta-xylanase C [Medicago truncatula] gi|357503165|ref|XP_003621871.1|
Domains
13
Lj3g3v3500170.1
– PREDICTED: endo-1,4-beta-xylanase Z-like [Glycine max] gi|356541019|ref|XP_003538981.1|
Domains
17
Lj5g3v2099500.1
– PREDICTED: endo-1,4-beta-xylanase A-like [Cicer arietinum] gi|502120176|ref|XP_004496873.1|
Domains
21
Lj5g3v2099500.2
– Endo-1,4-beta-xylanase A [Medicago truncatula] gi|357444483|ref|XP_003592519.1|
Domains
21
LotjaGi1g1v0364800.1
– Endo-1,4-beta-xylanase, putative, expressed; TAIR: AT1G58370.1 glycosyl hydrolase family 10 protein / carbohydrate-binding domain-containing protein; Swiss-Prot: sp|A3DH97|RSGI6_CLOTH Anti-sigma-I factor RsgI6; TrEMBL-Plants: tr|I1K8B0|I1K8B0_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0364800
Domains
17
LotjaGi1g1v0364800.2
– Endo-1,4-beta-xylanase, putative, expressed; TAIR: AT1G58370.2 glycosyl hydrolase family 10 protein / carbohydrate-binding domain-containing protein; Swiss-Prot: sp|A3DH97|RSGI6_CLOTH Anti-sigma-I factor RsgI6; TrEMBL-Plants: tr|I1K8B0|I1K8B0_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0364800
Domains
16
LotjaGi1g1v0559800.1
– Endo-1,4-beta-xylanase; TAIR: AT4G38650.1 Glycosyl hydrolase family 10 protein; Swiss-Prot: sp|A3DH97|RSGI6_CLOTH Anti-sigma-I factor RsgI6; TrEMBL-Plants: tr|A0A0B2QJS4|A0A0B2QJS4_GLYSO Endo-1,4-beta-xylanase A; Found in the gene: LotjaGi1g1v0559800
Domains
19
LotjaGi1g1v0559800.2
– Endo-1,4-beta-xylanase; TAIR: AT4G38650.1 Glycosyl hydrolase family 10 protein; Swiss-Prot: sp|A3DH97|RSGI6_CLOTH Anti-sigma-I factor RsgI6; TrEMBL-Plants: tr|A0A0B2QJS4|A0A0B2QJS4_GLYSO Endo-1,4-beta-xylanase A; Found in the gene: LotjaGi1g1v0559800
Domains
12
LotjaGi3g1v0524400.1
– Endo-1,4-beta-xylanase; TAIR: AT4G33840.1 Glycosyl hydrolase family 10 protein; Swiss-Prot: sp|A3DH97|RSGI6_CLOTH Anti-sigma-I factor RsgI6; TrEMBL-Plants: tr|A0A072UFN4|A0A072UFN4_MEDTR Glycosyl hydrolase family 10 protein; Found in the gene: LotjaGi3g1v0524400
Domains
23
LotjaGi5g1v0039300.1
– Endo-1,4-beta-xylanase A; TAIR: AT1G58370.2 glycosyl hydrolase family 10 protein / carbohydrate-binding domain-containing protein; Swiss-Prot: sp|A3DH97|RSGI6_CLOTH Anti-sigma-I factor RsgI6; TrEMBL-Plants: tr|K7M5U1|K7M5U1_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0039300
Domains
16
LotjaGi5g1v0039300.2
– Endo-1,4-beta-xylanase A; TAIR: AT1G58370.1 glycosyl hydrolase family 10 protein / carbohydrate-binding domain-containing protein; Swiss-Prot: sp|A3DH97|RSGI6_CLOTH Anti-sigma-I factor RsgI6; TrEMBL-Plants: tr|K7M5U2|K7M5U2_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0039300
Domains
16
LotjaGi5g1v0039300.3
– Endo-1,4-beta-xylanase A; TAIR: AT1G58370.2 glycosyl hydrolase family 10 protein / carbohydrate-binding domain-containing protein; Swiss-Prot: sp|A3DH97|RSGI6_CLOTH Anti-sigma-I factor RsgI6; TrEMBL-Plants: tr|K7M5U1|K7M5U1_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0039300
Domains
16
LotjaGi5g1v0039300.4
– Endo-1,4-beta-xylanase, putative, expressed; TAIR: AT1G58370.1 glycosyl hydrolase family 10 protein / carbohydrate-binding domain-containing protein; Swiss-Prot: sp|A3DH97|RSGI6_CLOTH Anti-sigma-I factor RsgI6; TrEMBL-Plants: tr|A0A0S3RPM8|A0A0S3RPM8_PHAAN Uncharacterized protein; Found in the gene: LotjaGi5g1v0039300
Domains
16
LotjaGi5g1v0039300.5
– Endo-1,4-beta-xylanase A; TAIR: AT1G58370.1 glycosyl hydrolase family 10 protein / carbohydrate-binding domain-containing protein; Swiss-Prot: sp|A3DH97|RSGI6_CLOTH Anti-sigma-I factor RsgI6; TrEMBL-Plants: tr|K7M5U2|K7M5U2_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0039300
Domains
16
LotjaGi5g1v0039300.6
– Endo-1,4-beta-xylanase A; TAIR: AT1G58370.1 glycosyl hydrolase family 10 protein / carbohydrate-binding domain-containing protein; Swiss-Prot: sp|A3DH97|RSGI6_CLOTH Anti-sigma-I factor RsgI6; TrEMBL-Plants: tr|K7M5U2|K7M5U2_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0039300
Domains
16
LotjaGi5g1v0039300.7
– Endo-1,4-beta-xylanase A; TAIR: AT1G58370.1 glycosyl hydrolase family 10 protein / carbohydrate-binding domain-containing protein; Swiss-Prot: sp|A3DH97|RSGI6_CLOTH Anti-sigma-I factor RsgI6; TrEMBL-Plants: tr|K7M5U1|K7M5U1_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0039300
Domains
15
LotjaGi5g1v0322000.1
– Endo-1,4-beta-xylanase; TAIR: AT2G14690.1 Glycosyl hydrolase superfamily protein; Swiss-Prot: sp|A3DH97|RSGI6_CLOTH Anti-sigma-I factor RsgI6; TrEMBL-Plants: tr|G7IEW9|G7IEW9_MEDTR Glycosyl hydrolase family 10 protein; Found in the gene: LotjaGi5g1v0322000
Domains
9
LotjaGi5g1v0322100.1
– Endo-1,4-beta-xylanase; TAIR: AT4G33840.1 Glycosyl hydrolase family 10 protein; Swiss-Prot: sp|A3DH97|RSGI6_CLOTH Anti-sigma-I factor RsgI6; TrEMBL-Plants: tr|G7IEW9|G7IEW9_MEDTR Glycosyl hydrolase family 10 protein; Found in the gene: LotjaGi5g1v0322100
Domains
20

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
TMhelix TMHMM 1 4.17