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IPR001017

Source: InterPro

Description

IPR001017 is a Dehydrogenase, E1 component.

<p>This entry represents a domain found in a number of dehydrogenases, all of which use thiamine pyrophosphate as a cofactor and are members of a multienzyme complex: <ul> <li>pyruvate dehydrogenase ([ec:1.2.4.1]), a component of the multienzyme pyruvate dehydrogenase complex</li> <li>2-oxoglutarate dehydrogenase ([ec:1.2.4.2]), a component of the multienzyme 2-oxoglutarate dehydrogenase, which contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)</li> <li>2-oxoisovalerate dehydrogenase ([ec:1.2.4.4]), a component of the multienzyme branched-chain alpha-keto dehydrogenase complex.</li></ul>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0016624
Molecular function Oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces a disulfide.
Subterm of

Associated Lotus transcripts 25

Transcript Name Description Predicted domains Domain count
Lj0g3v0065549.1
– PREDICTED: 2-oxoglutarate dehydrogenase, mitochondrial-like [Glycine max] gi|356568971|ref|XP_003552681.1|
Domains
14
Lj0g3v0065559.1
– PREDICTED: 2-oxoglutarate dehydrogenase, mitochondrial-like [Glycine max] gi|356568971|ref|XP_003552681.1|
Domains
14
Lj1g3v0912020.1
– PREDICTED: 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial-like [Glycine max] gi|356515957|ref|XP_003526663.1|
Domains
13
Lj1g3v1340510.1
– 2-oxoisovalerate dehydrogenase subunit alpha [Medicago truncatula] gi|357464693|ref|XP_003602628.1|
Domains
8
Lj2g3v1365830.1
– Pyruvate dehydrogenase, partial [Citrus x paradisi] gi|68138987|gb|AAY86036.1|
Domains
13
Lj3g3v2517580.1
– PREDICTED: pyruvate dehydrogenase E1 component subunit alpha-like [Glycine max] gi|356559679|ref|XP_003548126.1|
Domains
11
Lj5g3v2264090.1
– PREDICTED: 2-oxoglutarate dehydrogenase, mitochondrial-like [Glycine max] gi|356575371|ref|XP_003555815.1|
Domains
18
LotjaGi1g1v0271300.1
– Pyruvate dehydrogenase E1 component alpha subunit; TAIR: AT5G09300.1 Thiamin diphosphate-binding fold (THDP-binding) superfamily protein; Swiss-Prot: sp|Q84JL2|ODBA2_ARATH 2-oxoisovalerate dehydrogenase subunit alpha 2, mitochondrial; TrEMBL-Plants: tr|I1KAH2|I1KAH2_SOYBN Branched-chain alpha keto-acid dehydrogenase E1 alpha subunit-like protein; Found in the gene: LotjaGi1g1v0271300
Domains
13
LotjaGi1g1v0271300.2
– Pyruvate dehydrogenase E1 component alpha subunit; TAIR: AT5G09300.1 Thiamin diphosphate-binding fold (THDP-binding) superfamily protein; Swiss-Prot: sp|Q84JL2|ODBA2_ARATH 2-oxoisovalerate dehydrogenase subunit alpha 2, mitochondrial; TrEMBL-Plants: tr|A0A072V066|A0A072V066_MEDTR 2-oxoisovalerate dehydrogenase subunit alpha; Found in the gene: LotjaGi1g1v0271300
Domains
8
LotjaGi1g1v0271300.3
– Pyruvate dehydrogenase E1 component subunit alpha; TAIR: AT5G09300.1 Thiamin diphosphate-binding fold (THDP-binding) superfamily protein; Swiss-Prot: sp|Q84JL2|ODBA2_ARATH 2-oxoisovalerate dehydrogenase subunit alpha 2, mitochondrial; TrEMBL-Plants: tr|A0A072V066|A0A072V066_MEDTR 2-oxoisovalerate dehydrogenase subunit alpha; Found in the gene: LotjaGi1g1v0271300
Domains
8
LotjaGi1g1v0320700.1
– Pyruvate dehydrogenase E1 component alpha subunit; TAIR: AT5G09300.1 Thiamin diphosphate-binding fold (THDP-binding) superfamily protein; Swiss-Prot: sp|Q84JL2|ODBA2_ARATH 2-oxoisovalerate dehydrogenase subunit alpha 2, mitochondrial; TrEMBL-Plants: tr|G7JBL9|G7JBL9_MEDTR 2-oxoisovalerate dehydrogenase E1 component, alpha subunit; Found in the gene: LotjaGi1g1v0320700
Domains
8
LotjaGi1g1v0320700.2
– Pyruvate dehydrogenase E1 component alpha subunit; TAIR: AT5G09300.1 Thiamin diphosphate-binding fold (THDP-binding) superfamily protein; Swiss-Prot: sp|Q84JL2|ODBA2_ARATH 2-oxoisovalerate dehydrogenase subunit alpha 2, mitochondrial; TrEMBL-Plants: tr|G7JBL9|G7JBL9_MEDTR 2-oxoisovalerate dehydrogenase E1 component, alpha subunit; Found in the gene: LotjaGi1g1v0320700
Domains
8
LotjaGi1g1v0535400.1
– 2-oxoglutarate dehydrogenase E1 component family protein; TAIR: AT3G55410.1 2-oxoglutarate dehydrogenase, E1 component; Swiss-Prot: sp|Q54JE4|ODO1_DICDI 2-oxoglutarate dehydrogenase, mitochondrial; TrEMBL-Plants: tr|A0A0L9UWY3|A0A0L9UWY3_PHAAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0535400
Domains
22
LotjaGi1g1v0535400.2
– 2-oxoglutarate dehydrogenase E1 component family protein; TAIR: AT5G65750.1 2-oxoglutarate dehydrogenase, E1 component; Swiss-Prot: sp|Q54JE4|ODO1_DICDI 2-oxoglutarate dehydrogenase, mitochondrial; TrEMBL-Plants: tr|A0A0L9UWY3|A0A0L9UWY3_PHAAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0535400
Domains
22
LotjaGi1g1v0535400.3
– 2-oxoglutarate dehydrogenase E1 component family protein; TAIR: AT5G65750.1 2-oxoglutarate dehydrogenase, E1 component; Swiss-Prot: sp|Q54JE4|ODO1_DICDI 2-oxoglutarate dehydrogenase, mitochondrial; TrEMBL-Plants: tr|A0A0L9UWY3|A0A0L9UWY3_PHAAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0535400
Domains
22
LotjaGi1g1v0535400.4
– 2-oxoglutarate dehydrogenase E1 component family protein; TAIR: AT3G55410.1 2-oxoglutarate dehydrogenase, E1 component; Swiss-Prot: sp|Q54JE4|ODO1_DICDI 2-oxoglutarate dehydrogenase, mitochondrial; TrEMBL-Plants: tr|A0A0L9UWY3|A0A0L9UWY3_PHAAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0535400
Domains
22
LotjaGi2g1v0312700.1
– Pyruvate dehydrogenase E1 component subunit alpha; TAIR: AT1G59900.1 pyruvate dehydrogenase complex E1 alpha subunit; Swiss-Prot: sp|P52902|ODPA_PEA Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial; TrEMBL-Plants: tr|V7CHA1|V7CHA1_PHAVU Pyruvate dehydrogenase E1 component subunit alpha; Found in the gene: LotjaGi2g1v0312700
Domains
13
LotjaGi3g1v0403700.1
– Pyruvate dehydrogenase E1 component subunit alpha; TAIR: AT1G01090.1 pyruvate dehydrogenase E1 alpha; Swiss-Prot: sp|O24457|ODPA3_ARATH Pyruvate dehydrogenase E1 component subunit alpha-3, chloroplastic; TrEMBL-Plants: tr|A0A0B2Q7E3|A0A0B2Q7E3_GLYSO Pyruvate dehydrogenase E1 component subunit alpha; Found in the gene: LotjaGi3g1v0403700
Domains
11
LotjaGi3g1v0403700.2
– Pyruvate dehydrogenase E1 component subunit alpha; TAIR: AT1G01090.1 pyruvate dehydrogenase E1 alpha; Swiss-Prot: sp|O24457|ODPA3_ARATH Pyruvate dehydrogenase E1 component subunit alpha-3, chloroplastic; TrEMBL-Plants: tr|A0A0B2Q7E3|A0A0B2Q7E3_GLYSO Pyruvate dehydrogenase E1 component subunit alpha; Found in the gene: LotjaGi3g1v0403700
Domains
11
LotjaGi3g1v0403700.3
– Pyruvate dehydrogenase E1 component subunit alpha; TAIR: AT1G01090.1 pyruvate dehydrogenase E1 alpha; Swiss-Prot: sp|O24457|ODPA3_ARATH Pyruvate dehydrogenase E1 component subunit alpha-3, chloroplastic; TrEMBL-Plants: tr|A0A0B2Q7E3|A0A0B2Q7E3_GLYSO Pyruvate dehydrogenase E1 component subunit alpha; Found in the gene: LotjaGi3g1v0403700
Domains
11
LotjaGi3g1v0403700.4
– Pyruvate dehydrogenase E1 component subunit alpha; TAIR: AT1G01090.1 pyruvate dehydrogenase E1 alpha; Swiss-Prot: sp|O24457|ODPA3_ARATH Pyruvate dehydrogenase E1 component subunit alpha-3, chloroplastic; TrEMBL-Plants: tr|A0A0B2Q7E3|A0A0B2Q7E3_GLYSO Pyruvate dehydrogenase E1 component subunit alpha; Found in the gene: LotjaGi3g1v0403700
Domains
11
LotjaGi5g1v0356200.1
– 2-oxoglutarate dehydrogenase E1 component family protein; TAIR: AT5G65750.1 2-oxoglutarate dehydrogenase, E1 component; Swiss-Prot: sp|Q54JE4|ODO1_DICDI 2-oxoglutarate dehydrogenase, mitochondrial; TrEMBL-Plants: tr|A0A072W2L0|A0A072W2L0_MEDTR E1 subunit-like 2-oxoglutarate dehydrogenase; Found in the gene: LotjaGi5g1v0356200
Domains
22
LotjaGi5g1v0356200.3
– 2-oxoglutarate dehydrogenase E1 component family protein; TAIR: AT5G65750.1 2-oxoglutarate dehydrogenase, E1 component; Swiss-Prot: sp|Q54JE4|ODO1_DICDI 2-oxoglutarate dehydrogenase, mitochondrial; TrEMBL-Plants: tr|A0A072W2L0|A0A072W2L0_MEDTR E1 subunit-like 2-oxoglutarate dehydrogenase; Found in the gene: LotjaGi5g1v0356200
Domains
22
LotjaGi5g1v0356200.4
– 2-oxoglutarate dehydrogenase E1 component family protein; TAIR: AT5G65750.1 2-oxoglutarate dehydrogenase, E1 component; Swiss-Prot: sp|Q54JE4|ODO1_DICDI 2-oxoglutarate dehydrogenase, mitochondrial; TrEMBL-Plants: tr|A0A072W2L0|A0A072W2L0_MEDTR E1 subunit-like 2-oxoglutarate dehydrogenase; Found in the gene: LotjaGi5g1v0356200
Domains
22
LotjaGi5g1v0356200.5
– 2-oxoglutarate dehydrogenase E1 component family protein; TAIR: AT5G65750.1 2-oxoglutarate dehydrogenase, E1 component; Swiss-Prot: sp|Q54JE4|ODO1_DICDI 2-oxoglutarate dehydrogenase, mitochondrial; TrEMBL-Plants: tr|A0A072W2L0|A0A072W2L0_MEDTR E1 subunit-like 2-oxoglutarate dehydrogenase; Found in the gene: LotjaGi5g1v0356200
Domains
22

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
cd02016 CDD 1 4.00